Final Program

400 WEDNESDAY • MAY 18
3:00 Accelerated Ticking of the Epigenetic Clock in Smokers with
and Without COPD/D.L. DeMeo, J.D. Morrow, C.P. Hersh, V.
Pinto-Plata, B. Celli, N. Marchetti, G.J. Criner, R. Bueno, G.
Washko, E.K. Silverman, W. Qiu, Boston, MA, p.A7479
3:15 Clinical and Genetic Characteristics of Emphysema
Distribution Subtypes Identified by Unsupervised Learning
Analysis/A. El Boueiz, M.H. Cho, G. Washko, R. San Jose
Estepar, D.A. Lynch, J.D. Crapo, E.K. Silverman, D.L. DeMeo, P.J.
Castaldi, Boston, MA, p.A7480
D92
MINI SYMPOSIUM
REFINING THE EVALUATION AND TREATMENT OF
CYSTIC FIBROSIS
1:30 p.m. - 3:30 p.m. MOSCONE CENTER
Chairing: M. Jain, MD, Chicago, IL
J.L. Taylor-Cousar, MD, Denver, CO
S.M. Rowe, MD, Birmingham, AL
Featured Speaker
Room 2020/2022 (West Building, Level 2)
1:30 The Future of Cystic Fibrosis Care/D.E. Tullis, MD, Toronto,
Canada,
Oral Presentations
1:45 Association of Sweat Chloride Level with Mortality Varies by
Individual Cystic Fibrosis Transmembrane Receptor
Genotype/J. Espel, H. Palac, J. Ciolino, J. Cullina, M. Jain,
Chicago, IL, p.A7481
2:00 Genetic Variation in CFTR Allele Mutations and ADRB2
Polymorphisms Influence Cardiac Hemodynamic Responses to
Albuterol in Individuals with Cystic Fibrosis/E.H. Van Iterson,
S.E. Baker, C.M. Wheatley, W.J. Morgan, E.M. Snyder, Rochester,
MN, p.A7482
2:15 High Sensitivity C-Reactive Protein in Adult Patients with
Cystic Fibrosis Pulmonary Exacerbations/T. Kyaw, M. Callahan,
R. Klingsberg, A.H. Alraiyes, F. Kheir, New Orleans, LA, p.A7483
2:30 Prognostic Value of Pulmonary Hypertension in Patients with
Cystic Fibrosis/D. Li, F. Wen, L. Gao, Baltimore, MD, p.A7484
2:45 Cystic Fibrosis Related Diabetes: An Audit/O. O’Carroll, D.
Hughes, C. McCarthy, D. Smith, C. Gunaratnam, N.G. McElvaney,
Dublin, Ireland, p.A7485
3:00 Durable Improvement in Mucociliary Clearance Following a
Single Dose of Hypertonic Saline in Cystic Fibrosis/A. Trimble,
B. Laube, W. Brown, K.L. Zeman, N. Lechtzin, J. Wu, D. Waltz,
W.D. Bennett, S. Donaldson, Chapel Hill, NC, p.A7486
3:15 Relationship Between Throat Culture, Sputum Culture, and
Lower Respiratory Tract Culture in Adult Patients with Cystic
Fibrosis/D. Seidler, M. Griffin, A.B. Nymon, J. Schwartzman, K.
Koeppen, A. Ashare, Lebanon, NH, p.A7487
D93
MINI SYMPOSIUM
RESPIRATORY FAILURE: ADVANCED
MECHANISTIC INSIGHTS INFORMING
TRANSLATION IN ACUTE LUNG INJURY/ARDS
1:30 p.m. - 3:30 p.m. MOSCONE CENTER
Chairing: C.C. Dos Santos, MD, Toronto, Canada
C. Mikacenic, MD, Seattle, WA
J.R. Jacobson, MD, Chicago, IL
Oral Presentations
Room 3006/3008 (West Building, Level 3)
1:30 An Angiopoietin-2 Genetic Variant Associated with Plasma
Angiopoietin-2 Is a Risk Factor for Sepsis-Associated
ARDS/N.J. Meyer, J.P. Reilly, T.G. Dunn, J. Abbott, F. Wang, B.
Lim, C.A.G. Ittner, B.J. Anderson, M.G.S. Shashaty, J.A.
Palakshappa, M.A. Matthay, C.S. Calfee, R. Feng, J.D. Christie,
Philadelphia, PA, p.A7488
1:45 A Functional Missense SNP in LRRC16A Contributes to an
Improved Prognosis of ARDS Patients Mediated Through
Attenuated Platelet Count Decline in ICU/Z. Wang, Y. Wei, P.
Tejera, L. Su, E.K. Bajwa, D.C. Christiani, Boston, MA, p.A7489
2:00 ABO Genetic Variation and Acute Respiratory Distress
Syndrome Risk in Sepsis/J.P. Reilly, N.J. Meyer, M.G.S.
Shashaty, B.J. Anderson, J.A. Palakshappa, C.A.G. Ittner, C.S.
Calfee, M. Matthay, Z. Wang, C. Mikacenic, X. Lin, I. Barnett, K.
Walley, J.A. Russell, D.C. Christiani, M.M. Wurfel, J.D. Christie,
Philadelphia, PA, p.A7490
2:15 Haptoglobin 2:2 Genotype Is Associated with Acute
Respiratory Distress Syndrome in Patients with Severe
Trauma/H. Nagata, J.B. McNeil, N. Wickersham, C.M. Shaver,
N.D. Putz, J.L. Kuck, J.A. Bastarache, L. Ware, Nashville, TN,
p.A7491
2:30 Critical Role of
Phosphofructokinase-2/Fructose-2,6-Bisphosphatase (PFKFB)
3 in Acute Lung Injury/C. Vohwinkel, N. Burns, J. Kraynik, K.R.
Stenmark, H. Eltzschig, Aurora, CO, p.A7492
2:45 RAGE Modulation Influences Lung Injury and AFC: In Vivo and
Vitro Studies/R. Blondonnet, J. Audard, J. Lutz, G. Clairefond, C.
Belville, D. Bouvier, L. Blanchon, J.-L. Couderc, C. Damon, V.
Sapin, J.-M. Constantin, M. Jabaudon, Clermont-Ferrand, France,
p.A7493
3:00 Human Mesenchymal Stem Cell Derived Microvesicles
Attenuate Acute Lung Injury in Mice Partly Via Transferring
Ang-1 mRNA/X.-D. Tang, L. Shi, A. Monsel, X.-Y. Li, H.-L. Zhu,
Y.-G. Zhu, J.-M. Qu, Shanghai, China, p.A7494
3:15 Therapeutic Effects of Human Bone Marrow Derived
Mesenchymal Stem Cell Microvesicles in an Ex Vivo Perfused
Human Lung Injured with Severe E.coli Pneumonia/J. Park, H.
Lim, S. Hu, Q. Hao, M.A. Matthay, J.W. Lee, San Francisco, CA,
p.A7495
ATS 2016 • San Francisco