Final Program
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300 TUESDAY • MAY 17<br />
P1363<br />
P1364<br />
P1365<br />
P1366<br />
P1367<br />
P1368<br />
P1369<br />
P1370<br />
P1371<br />
P1372<br />
P1373<br />
P1374<br />
Generation of Functional Lung Organoids that Resemble the<br />
Human Small Airway Epithelia/K. White, S. Raja, M. Dowling, K.<br />
Subramanian, Cambridge, MA, p.A5867<br />
p53- and PAI-1-Mediated Induction of C-X-C Chemokines and<br />
CXCR2: Importance in Pulmonary Inflammation Due to<br />
Cigarette Smoke Exposure/N. Tiwari, A.S. Marudamuthu, B.<br />
Puthusseri, S. Idell, S. Shetty, Tyler, TX, p.A5868<br />
Acquired CFTR Dysfunction Is Associated with Bronchiectasis<br />
in Smokers and Former Smokers with Chronic Obstructive<br />
Pulmonary Disease/K. Teerapuncharoen, J.M. Wells, S.V. Raju, L.<br />
Rasmussen, H. Nath, A.A. Diaz, R. San Jose Estepar, G. Washko,<br />
S.P. Bhatt, G.M. Solomon, M.T. Dransfield, S.M. Rowe,<br />
Birmingham, AL, p.A5869<br />
Monitoring Local Pulmonary cAMP Levels: Combining<br />
Precision Cut Lung Slice (PCLS) and Fluorescence Resonance<br />
Energy Transfer (FRET) Technologies in Mice/H. Zuo, W.J.<br />
Poppinga, E. Zeisberg, V.O. Nikolaev, M. Schmidt, Groningen,<br />
Netherlands, p.A5870<br />
Effects of Two Doses of Bone Marrow-Derived Mesenchymal<br />
Stromal Cells in a Model of Elastase-Induced Severe<br />
Emphysema/H.A. Poggio, N.N. Rocha, J.Z. Kitoko, M.M. Morales,<br />
P.C. Olsen, P.R.M. Rocco, M.A. Antunes, F.F. Cruz, Rio de<br />
Janeiro, Brazil, p.A5871<br />
Epac1 and Epac2 Regulate Airway Smooth Muscle Tone in<br />
Mice/M. Schmidt, A. Oldenburger, C. Elzinga, H. Maarsingh,<br />
Groningen, Netherlands, p.A5872<br />
Impact of Tobacco Smoking on Extracellular IL-17A Protein in<br />
the Peripheral Airways/B. Levanen, P. Glader, B. Dahlen, B.<br />
Billing, L. Palmberg, I. Qvarfordt, K. Larsson, A. Linden, Stockholm,<br />
Sweden, p.A5873<br />
Differential Induction of MUC5AC Mucin Gene Expression by<br />
Haemophilus spp. Isolated from Patients with COPD/A. Tariq,<br />
C. Wrona, S. Sethi, Buffalo, NY, p.A5874<br />
Smoking-Induced Up-Regulation of KLF4 Modulates Partial<br />
Somatic Cell- Reprogramming-Like in the Human Airway<br />
Epithelium/G. Wang, X. Ou, H. Zhou, J. Salit, Y. Strulovici-Barel,<br />
R.J. Kaner, R.G. Crystal, New York, NY, p.A5875<br />
Characterization of the Chloride/Bicarbonate Exchanger<br />
Pendrin (SLC26A4) in Airway Epithelia Implicates Pendrin as a<br />
Potential Mediator of Mucus Hypersecretion and Airway<br />
Surface Liquid Dehydration/B. Bennett, X. Zhang, J. Whoriskey,<br />
M. Fiorino, J. Yu, D. Kaufman, K. Rohrbach, E. Valente, F.-F. Lin,<br />
G. Li, S. Matyas, S. Davis, J.A. Johnston, J.E. Phillips, Thousand<br />
Oaks, CA, p.A5876<br />
Mechanisms of Alveolar Type II Cell Injury in Emphysema/K.<br />
Bahmed, E. Messier, R. Tuder, J. Mitchell, H.W. Chu, R.P. Bowler,<br />
R. Mason, B. Kosmider, Philadelphia, PA, p.A5877<br />
b-Catenin in COPD - a Role for Both Inhibitors and<br />
Activators/K. Rydell-Tormanen, X.-H. Zhou, O. Hallgren, L.<br />
Eriksson, A. Andersson-Sjoland, G. Westergren-Thorsson, Lund,<br />
Sweden, p.A5878<br />
P1375<br />
P1376<br />
C72<br />
Oxidant-Induced Autophagy and Ferritin Degradation: A Novel<br />
Pathway through Lysosomal Iron to Epithelial-Mesenchymal<br />
Transition/A. Sioutas, L. Vainikka, M. Kentson, S. Dam-Larsen, U.<br />
Wennerstrom, P. Jacobson, H.L. Persson, Linkoping, Sweden,<br />
p.A5879<br />
Altered Redox and Metabolic Status in Airway Smooth Muscle<br />
Cells of Patients with COPD/C. Michaeloudes, C.-H. Kuo, I.M.<br />
Adcock, K.F. Chung, London, United Kingdom, p.A5880<br />
THEMATIC POSTER SESSION<br />
EPITHELIAL BIOLOGY<br />
9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />
Viewing: Posters will be on display for entire session.<br />
Area H, Hall D (North Building, Lower Level)<br />
Discussion: 11:00-11:45: authors will be present for individual discussion<br />
11:45-12:45: authors will be present for discussion with assigned facilitators<br />
Facilitator:<br />
P897<br />
P898<br />
P899<br />
P900<br />
P901<br />
P902<br />
Facilitator:<br />
P903<br />
L.A. Dada, PhD, Chicago, IL<br />
Production of Inflammatory Mediators and Induction of<br />
Apoptosis in Pleural Mesothelial Cells, Lung and Breast<br />
Cancer Cells Exposed to Talc Particles/M.M.P. Acencio, L.R.<br />
Teixeira, V.A. Alvarenga, C.S.R. Silva, R.K.B. Sales, E. Marchi,<br />
Sao Paulo, Brazil, p.A5881<br />
Glycogen Synthase Kinase-3b Induces Mesenchymal<br />
Transition (MesoMT) of Human Pleural Mesothelial Cells/T.A.<br />
Tucker, A. Jeffers, S. Owens, G. Shryock, J. Boren, K. Koenig, S.<br />
Idell, Tyler, TX, p.A5882<br />
Regulatory Roles of cAMP in Epithelial-Mesenchymal<br />
Transition in Lung Epithelial Cells/R. Kikuchi, T. Tsuji, H.<br />
Nakamura, K. Aoshiba, Ibaraki, Japan, p.A5883<br />
Proprotein Convertase Paired Basic Amino Acid-Cleaving<br />
Enzyme 4 (PACE4) Is Involved in the Maturation of Integrin<br />
AlphaV in Human Nasal Epithelial Cells/S.-N. Lee, J.-H. Yoon,<br />
Seoul, Korea, Republic of, p.A5884<br />
Airway Smooth Muscle Conditioned Meida Protets Airway<br />
Epithelial Cells from Viral-Induced Glucocorticoid<br />
Insensitivity/Y.C. Xia, S. Langenbach, C.R. Keenan, R.C.<br />
Gualano, A.G. Stewart, Parkville, Australia, p.A5885<br />
Viral Infection Induces Airway Epithelial<br />
Glucocorticoid-Insensitivity/Y.C. Xia, S. Langenbach, C.R.<br />
Keenan, A. Radwan, S. Londrigan, R.C. Gualano, A.G. Stewart,<br />
Parkville, Australia, p.A5886<br />
S. Idell, MD, PhD, Tyler, TX<br />
Towards Therapeutic Alveolar Regeneration - Characterization<br />
of a Novel Wnt-Responsive Subpopulation of Type II<br />
Pneumocyte which Exhibits Increased Progenitor Cell<br />
Function in the Adult Mammalian Lung/W.J. Zacharias, D.<br />
Frank, J. Zepp, M. Morley, E.E. Morrisey, Philadelphia, PA,<br />
p.A5887<br />
ATS 2016 • San Francisco