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300 TUESDAY • MAY 17<br />

P1363<br />

P1364<br />

P1365<br />

P1366<br />

P1367<br />

P1368<br />

P1369<br />

P1370<br />

P1371<br />

P1372<br />

P1373<br />

P1374<br />

Generation of Functional Lung Organoids that Resemble the<br />

Human Small Airway Epithelia/K. White, S. Raja, M. Dowling, K.<br />

Subramanian, Cambridge, MA, p.A5867<br />

p53- and PAI-1-Mediated Induction of C-X-C Chemokines and<br />

CXCR2: Importance in Pulmonary Inflammation Due to<br />

Cigarette Smoke Exposure/N. Tiwari, A.S. Marudamuthu, B.<br />

Puthusseri, S. Idell, S. Shetty, Tyler, TX, p.A5868<br />

Acquired CFTR Dysfunction Is Associated with Bronchiectasis<br />

in Smokers and Former Smokers with Chronic Obstructive<br />

Pulmonary Disease/K. Teerapuncharoen, J.M. Wells, S.V. Raju, L.<br />

Rasmussen, H. Nath, A.A. Diaz, R. San Jose Estepar, G. Washko,<br />

S.P. Bhatt, G.M. Solomon, M.T. Dransfield, S.M. Rowe,<br />

Birmingham, AL, p.A5869<br />

Monitoring Local Pulmonary cAMP Levels: Combining<br />

Precision Cut Lung Slice (PCLS) and Fluorescence Resonance<br />

Energy Transfer (FRET) Technologies in Mice/H. Zuo, W.J.<br />

Poppinga, E. Zeisberg, V.O. Nikolaev, M. Schmidt, Groningen,<br />

Netherlands, p.A5870<br />

Effects of Two Doses of Bone Marrow-Derived Mesenchymal<br />

Stromal Cells in a Model of Elastase-Induced Severe<br />

Emphysema/H.A. Poggio, N.N. Rocha, J.Z. Kitoko, M.M. Morales,<br />

P.C. Olsen, P.R.M. Rocco, M.A. Antunes, F.F. Cruz, Rio de<br />

Janeiro, Brazil, p.A5871<br />

Epac1 and Epac2 Regulate Airway Smooth Muscle Tone in<br />

Mice/M. Schmidt, A. Oldenburger, C. Elzinga, H. Maarsingh,<br />

Groningen, Netherlands, p.A5872<br />

Impact of Tobacco Smoking on Extracellular IL-17A Protein in<br />

the Peripheral Airways/B. Levanen, P. Glader, B. Dahlen, B.<br />

Billing, L. Palmberg, I. Qvarfordt, K. Larsson, A. Linden, Stockholm,<br />

Sweden, p.A5873<br />

Differential Induction of MUC5AC Mucin Gene Expression by<br />

Haemophilus spp. Isolated from Patients with COPD/A. Tariq,<br />

C. Wrona, S. Sethi, Buffalo, NY, p.A5874<br />

Smoking-Induced Up-Regulation of KLF4 Modulates Partial<br />

Somatic Cell- Reprogramming-Like in the Human Airway<br />

Epithelium/G. Wang, X. Ou, H. Zhou, J. Salit, Y. Strulovici-Barel,<br />

R.J. Kaner, R.G. Crystal, New York, NY, p.A5875<br />

Characterization of the Chloride/Bicarbonate Exchanger<br />

Pendrin (SLC26A4) in Airway Epithelia Implicates Pendrin as a<br />

Potential Mediator of Mucus Hypersecretion and Airway<br />

Surface Liquid Dehydration/B. Bennett, X. Zhang, J. Whoriskey,<br />

M. Fiorino, J. Yu, D. Kaufman, K. Rohrbach, E. Valente, F.-F. Lin,<br />

G. Li, S. Matyas, S. Davis, J.A. Johnston, J.E. Phillips, Thousand<br />

Oaks, CA, p.A5876<br />

Mechanisms of Alveolar Type II Cell Injury in Emphysema/K.<br />

Bahmed, E. Messier, R. Tuder, J. Mitchell, H.W. Chu, R.P. Bowler,<br />

R. Mason, B. Kosmider, Philadelphia, PA, p.A5877<br />

b-Catenin in COPD - a Role for Both Inhibitors and<br />

Activators/K. Rydell-Tormanen, X.-H. Zhou, O. Hallgren, L.<br />

Eriksson, A. Andersson-Sjoland, G. Westergren-Thorsson, Lund,<br />

Sweden, p.A5878<br />

P1375<br />

P1376<br />

C72<br />

Oxidant-Induced Autophagy and Ferritin Degradation: A Novel<br />

Pathway through Lysosomal Iron to Epithelial-Mesenchymal<br />

Transition/A. Sioutas, L. Vainikka, M. Kentson, S. Dam-Larsen, U.<br />

Wennerstrom, P. Jacobson, H.L. Persson, Linkoping, Sweden,<br />

p.A5879<br />

Altered Redox and Metabolic Status in Airway Smooth Muscle<br />

Cells of Patients with COPD/C. Michaeloudes, C.-H. Kuo, I.M.<br />

Adcock, K.F. Chung, London, United Kingdom, p.A5880<br />

THEMATIC POSTER SESSION<br />

EPITHELIAL BIOLOGY<br />

9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />

Viewing: Posters will be on display for entire session.<br />

Area H, Hall D (North Building, Lower Level)<br />

Discussion: 11:00-11:45: authors will be present for individual discussion<br />

11:45-12:45: authors will be present for discussion with assigned facilitators<br />

Facilitator:<br />

P897<br />

P898<br />

P899<br />

P900<br />

P901<br />

P902<br />

Facilitator:<br />

P903<br />

L.A. Dada, PhD, Chicago, IL<br />

Production of Inflammatory Mediators and Induction of<br />

Apoptosis in Pleural Mesothelial Cells, Lung and Breast<br />

Cancer Cells Exposed to Talc Particles/M.M.P. Acencio, L.R.<br />

Teixeira, V.A. Alvarenga, C.S.R. Silva, R.K.B. Sales, E. Marchi,<br />

Sao Paulo, Brazil, p.A5881<br />

Glycogen Synthase Kinase-3b Induces Mesenchymal<br />

Transition (MesoMT) of Human Pleural Mesothelial Cells/T.A.<br />

Tucker, A. Jeffers, S. Owens, G. Shryock, J. Boren, K. Koenig, S.<br />

Idell, Tyler, TX, p.A5882<br />

Regulatory Roles of cAMP in Epithelial-Mesenchymal<br />

Transition in Lung Epithelial Cells/R. Kikuchi, T. Tsuji, H.<br />

Nakamura, K. Aoshiba, Ibaraki, Japan, p.A5883<br />

Proprotein Convertase Paired Basic Amino Acid-Cleaving<br />

Enzyme 4 (PACE4) Is Involved in the Maturation of Integrin<br />

AlphaV in Human Nasal Epithelial Cells/S.-N. Lee, J.-H. Yoon,<br />

Seoul, Korea, Republic of, p.A5884<br />

Airway Smooth Muscle Conditioned Meida Protets Airway<br />

Epithelial Cells from Viral-Induced Glucocorticoid<br />

Insensitivity/Y.C. Xia, S. Langenbach, C.R. Keenan, R.C.<br />

Gualano, A.G. Stewart, Parkville, Australia, p.A5885<br />

Viral Infection Induces Airway Epithelial<br />

Glucocorticoid-Insensitivity/Y.C. Xia, S. Langenbach, C.R.<br />

Keenan, A. Radwan, S. Londrigan, R.C. Gualano, A.G. Stewart,<br />

Parkville, Australia, p.A5886<br />

S. Idell, MD, PhD, Tyler, TX<br />

Towards Therapeutic Alveolar Regeneration - Characterization<br />

of a Novel Wnt-Responsive Subpopulation of Type II<br />

Pneumocyte which Exhibits Increased Progenitor Cell<br />

Function in the Adult Mammalian Lung/W.J. Zacharias, D.<br />

Frank, J. Zepp, M. Morley, E.E. Morrisey, Philadelphia, PA,<br />

p.A5887<br />

ATS 2016 • San Francisco

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