Final Program

254 TUESDAY • MAY 17
515 Roles of RAGE and TXNIP in NLRP3-Inflammasome Activation
in Human Macrophages/M. Jabaudon, J. Lutz, R. Blondonnet, C.
Belville, G. Clairefond, D. Bouvier, L. Blanchon, J.-L. Couderc, V.
Sapin, J.-M. Constantin, Clermont-Ferrand, France, p.A4803
516 Differential Effects of Antimicrobial Regimens in the
Regulation of Ventilator Induced Lung Injury Associated
Inflammasome Activation./D.S. Jones, I.I. Siempos, A.M.K. Choi,
New York, NY, p.A4804
517 Hypoxia Suppresses Innate Immune Function in Primary
Murine Alveolar Epithelial Cells Through Effects on the
Redox-Sensitive Factor, NFkB/A. Sturrock, D. Woller, R. Paine,
Salt Lake City, p.A4805
518 Redox Imbalance Induced by Angiotensin II Aggravated
Pulmonary Fibrosis Via Activating NALP3 Inflammasomes/
Y. Meng, Y. Chen, M. Pan, Q. Yang, Z. Zheng, Guangzhou, China,
p.A4806
519 RING Finger E3 Ligase PPP1R11 Regulates TLR2 Signaling
and Innate Immunity/B.B. Chen, A. Mckelvey, S. Dunn, T. Lear, Y.
Liu, Pittsburgh, PA, p.A4807
520 Asian Sand Dust Increases MUC8 and MUC5B Expressions Via
TLR4-Dependent ERK2 and p38 MAPK in Human Airway
Epithelial Cells/Y.-D. Kim, Y.S. Choi, H.G. Na, C.H. Bae, S.-Y.
Song, Daegu, Korea, Republic of, p.A4808
521 Lung WWOX Knockdown Causes Neutrophilic Inflammation
Associated with Increased Epithelial IL-8 Secretion/S. Singla, J.
Chen, J.R. Sysol, R.F. Machado, Chicago, IL, p.A4809
522 Notch Signaling in the Differentiation of Alveolar Type II to
Type I Cells After Pseudomonas Aeruginosa Induced Lung
Injury/J. Finn, Y. Liu, Chicago, IL, p.A7865
523 Functional Role of Pericytes in Lung Homeostasis and Acute
Lung Injury/C.F. Hung, Y.-H. Chow, W.A. Altemeier, L.M.
Schnapp, Seattle, WA, p.A7866
524 Duox2 Overexpression Can Control and Prevent Influenza A
Virus-Induced Acute Lung Infection/H.J. Kim, S.N. Hong, J.Y.
Kim, J.W. Lee, Seoul, Korea, Republic of, p.A7867
525 Diet-Induced Obesity Induces Endoplasmic Reticulum Stress
in the Lung Endothelium and Predispose to LPS Induced
Acute Lung Injury/D. Shah, F. Romero, R. Summer, Philadelphia,
PA, p.A7868
C30
POSTER DISCUSSION SESSION
ACUTE LUNG INJURY: CELL FUNCTION,
SIGNALING AND STRETCH
9:00 a.m. - 11:00 a.m. MOSCONE CENTER
Room 2024 (West Building, Level 2)
Poster Viewing 9:00-9:45
Discussion 9:45-11:00
Chairing: R.D. Hubmayr, MD, Rochester, MN
L.M. Schnapp, MD, Charleston, SC
D.W. Kaczka, MD, PhD, Iowa City, IA
601 Resident and Recruited Alveolar Macrophages Exhibit Distinct
and Dynamic Programming States Following Acute Lung
Injury/K.J. Mould, L. Barthel, M.P. Mohning, S. Leach, T. Danhorn,
P.M. Henson, W. Janssen, Aurora, CO, p.A4810
602 Deletion of c-FLIP in CD11b+ Macrophages Protects Against
Bleomycin Induced Lung Fibrosis/A.L. McCubbrey, L. Barthel,
W. Janssen, Denver, CO, p.A4811
603 High Fat Feeding Protects Mice from Ventilator-Induced Lung
Injury Via a Neutrophil-Independent Mechanism/M. Wilson, J.
Petrie, M. Shaw, C. Oakley, B.V. Patel, K.P. O’Dea, M. Takata,
London, United Kingdom, p.A4812
604 Pressure Dependent Alveolar Derecruitment Is Linked with
Surfactant Dysfunction in Bleomycin-Induced Acute Lung
Injury/L. Knudsen, E. Lopez-Rodriguez, L. Berndt, C. Boden, C.
Ruppert, J.H.T. Bates, M. Ochs, B.J. Smith, Hannover, Germany,
p.A4813
605 AMPing Up Lung Repair: The Interplay of Hypercapnia,
Adenylate Cyclase and AMP Kinase/R.A. Oeckler, S. Wang, D.N.
Schiavo, R. Stroetz, B. Walters, Rochester, MN, p.A4814
606 Lipopolysaccharide-Induced Lung Injury Is More Severe in Old
Compared to Young Mice/C. Brandenberger, K.M. Kling, E.
Lopez-Rodriguez, C. Pfarrer, C. Muhlfeld, Hannover, Germany,
p.A4815
607 Effects of Bacterial LPS on the Biomechanics of Alveolar
Epithelial Cells Measured by Atomic Force Microscopy/
V.R. Oliveira, J.J. Uriarte, W. Zin, R. Farre, D. Navajas, I.
Almendros, Barcelona, Spain, p.A4816
608 Lung Microenvironment Profiles in Mouse Models of Acute
Respiratory Distress Syndrome (ARDS)/A.A. Luo, D. Islam, A.
Grassi, D. Toumpanakis, B. Han, J.G. Laffey, M. Liu, A.S. Slutsky,
H. Zhang, Toronto, Canada, p.A4817
609 Rapid Quantification of Lung Inflation and Recruitment with
Automatic Lung Segmentation of Chest Computed
Tomography in a Variable Lung Collapse Model/J. Graf, A.
Santos, C. Silva, A. Salazar, P. Formenti, J.J. Marini, Santiago,
Chile, p.A4818
610 The Effects of Chest Wall Strapping in a Porcine Model of
ARDS/E. Abston, J. Herrmann, P. Taft, M. Eberlein, D.W. Kaczka,
D.A. Stoltz#, J. Zabner, Iowa City, IA, p.A4819
611 Multi-Frequency Oscillatory Ventilation (MFOV): Impact on
Eucapnic Ventilation Distribution in Simulated Lung Injury/J.
Herrmann, M.H. Tawhai, D.W. Kaczka, Iowa City, IA, p.A4820
612 Arginase Upregulation And Airway Hyperreactivity in Neonatal
Mice Exposed to Moderate Hyperoxia/I. Kuipers, M.A.
Thompson, M.R. Freeman, L.J. Manlove, R.D. Britt Jr., P.W.
MacFarlane, R.J. Martin, C.M. Pabelick, Y.S. Prakash, Rochester,
MN, p.A4821
613 Alpha-Klotho Protects Zucker Diabetic Fatty Rat Lung Against
Hyperoxic Injury/P. Ravikumar, E.V. Wechsler, O.W. Moe, C.C.W.
Hsia, Dallas, TX, p.A4822
614 Solubilized Lung-Derived Extracellular Matrix Mitigates
Hyperoxic Lung Injury/P. Ravikumar, C.T. Atkins, J. Wu, Y. Hong,
C.C.W. Hsia, Dallas, TX, p.A4823
ATS 2016 • San Francisco