Final Program

SUNDAY • MAY 15 33
A13
MINI SYMPOSIUM
NOVEL INNATE IMMUNE PATHWAYS IN SEVERE
ASTHMA
9:00 a.m. - 11:00 a.m. MOSCONE CENTER
Room 2005/2007 (West Building, Level 2)
Chairing: K.F. Chung, MD, PhD, London, United Kingdom
M. Idzko, MD, Freiburg, Germany
R.W. Harper, MD, Sacramento, CA
Oral Presentations
9:00 Macrophage Inflammasome Activation in Sputum from Severe
Asthmatics/S. Pavlidis, C. Rossios, M. Loza, F. Baribaud, A.
Rowe, C.H.S. Kuo, R. Lutter, U. Hoda, I. Pandis, Y.-K. Guo, A.R.
Sousa, J. Corfield, P.J. Sterk, R. Djukanovic, I. Adcock, K.F.
Chung, High Wycombe, United Kingdom, p.A1001
9:15 NLRP3 Inflammasome-Mediated, IL-1b-Dependent
Inflammatory Responses Drive Severe, Steroid-Insensitive
Asthma/R.Y. Kim, J.W. Pinkerton, A.-T. Essilfie, A.A. Robertson,
K.J. Baines, J.R. Mayall, M.R. Starkey, P.A. Wark, P.G. Gibson,
L.A. O’Neill, J.C. Horvat, M.A. Cooper, P.M. Hansbro, New
Lambton Heights, Australia, p.A1002
9:30 Overexpression of Gasdermin B, a Gene Target of the 17q12
Asthma-Susceptibility Regulatory Haplotype, Accentuates
Allergic Airway Inflammation/N. Krishnamoorthy, X. Zhou, M.A.
Perrella, B.D. Levy, B.A. Raby, Boston, MA, p.A1003
9:45 Airway Epithelial DUOX1 Mediates EGFR Activation, Mucus
Metaplasia, and Remodeling During Allergic Asthma/A. Van Der
Vliet, M. Hristova, A. Habibovic, D. Heppner, Y. Janssen-Heininger,
C.G. Irvin, M.E. Poynter, L.K.A. Lundblad, A.E. Dixon, M. Geiszt,
Burlington, VT, p.A1004
10:00 Role of Interferon Regulatory Factor-1 (IRF-1) in Modulating
Steroid Insensitive Pathways in Severe Asthma/A. Gavrila, L.
Chachi, O. Tliba, C.E. Brightling, Y. Amrani, Leicester, United
Kingdom, p.A1005
10:15 P2Y6R Signaling: A Double-Edged Sword in Allergen-Induced
Airway Inflammation/A. Zech, A. Meyer, M. Idzko, Freiburg,
Germany, p.A1006
10:30 1,25D3 Prevents CD8+Tc2 Skewing and Asthma Development
Through VDR Binding Changes to the Cyp11a1 Promoter/M.
Schedel, Y. Jia, S. Michel, K. Takeda, J. Domenico, A. Joetham, M.
Strand, J. Han, M. Wang, J.L. Lucas, C. Vogelberg, E.W. Gelfand,
M. Kabesch, B.P. O’Connor, Denver, CO, p.A1007
10:45 TSLP in Patients with Asthma, COPD and ACOS/P. Korosec, S.
Korn, S. Skrgat, R. Marcun, R. Buhl, M. Flezar, Golnik, Slovenia,
p.A1008
A14
MINI SYMPOSIUM
ADVANCE CARE PLANNING AND PALLIATIVE
CARE: PATIENTS TO POLICY
9:00 a.m. - 11:00 a.m. MOSCONE CENTER
Chairing: R.D. Stapleton, MD, PhD, Burlington, VT
E.K. Kross, MD, Seattle, WA
Oral Presentations
Room 307 (South Building, Esplanade Level)
9:00 Validation of a Prognostic Model to Predict 6-Month Mortality
in Medical Intensive Care Unit (MICU) Patients/R.G. Sangani, K.
Chapman, S. Hadique, S. Culp, S. Khan, J.E. Parker, A. Moss,
Morgantown, WV, p.A1009
9:15 Principles of End-of-Life Care for the Critically Ill: Sources of
Variability in Opinions About Autonomy, Advance Directives,
and Intensive Care Unit Interventions/A.C. Long, L. Downey,
E.K. Kross, R.A. Engelberg, M. Baras, J.R. Curtis, C.L. Sprung,
Seattle, WA, p.A1010
9:30 What Is Palliative Care’s Secret Ingredient? How Intensivists
and Palliative Care Physicians Navigate Communication with
Surrogates About a Patient’s Values and Preferences in
High-Fidelity Simulation/L.P. Scheunemann, P.S. Rajagopal,
R.M. Arnold, D.B. White, Pittsburgh, PA, p.A1011
9:45 Using the Early Warning System (EWS) to Identify and
Establish Goals of Care/Advanced Directives in a High Risk
Patient Population: A Randomized, Prospective Trial/D. Picker,
M. Dans, T. Bailey, K. Heard, M.H. Kollef, St. Louis, MO, p.A1012
10:00 Attitudes of Critical Care Clinicians Toward the Use of Triggers
for Intensive Care Unit-Based Palliative Care Consultation/
N.G. Wysham, D.M. Jones, W. Reagan, H. Goucher, S. Gundel,
C.T.L. Hough, J. Mcfarlin, M. Hua, C.E. Cox, Durham, NC, p.A1013
10:15 Advance Directives and Their Impact on Real-World Stability of
End-of-Life Preferences in Hospitalized Patients/Y.S. Kim, V.
Liu, P. Scheirer, J.D. Greene, G.J. Escobar, Oakland, CA, p.A1014
10:30 The Association Between Hospice Utilization and Performance
on Publicly Reported Outcome Measures/S. Lah, E. Wilson,
S.M. Brown, Murray, UT, p.A1015
10:45 Do Not Resuscitate Orders with Unplanned Hospital Readmission
Quality Measures in Pneumonia/A.B. Mehta, C.R. Cooke, I.S. Douglas,
P.K. Lindenauer, R.S. Wiener, A.J. Walkey, Boston, MA, p.A1016
A15
MINI SYMPOSIUM
EMERGING DATA ON COPD EXACERBATIONS
9:00 a.m. - 11:00 a.m. MOSCONE CENTER
Room 130-132 (North Building, Lower Level)
Chairing: J.A. Wedzicha, MD, PhD, London, United Kingdom
E.C. Oelsner, MD, MPH, New York, NY
S. Sethi, MD, Buffalo, NY
SUNDAY MORNING
ATS 2016 • San Francisco