Final Program
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152 MONDAY • MAY 16<br />
1015 Resveratrol Can Improve Chronic Hypoxia Induced Pulmonary<br />
Hypertension Only in Absence of Sirtuin 1 Catalytic Activity/<br />
M. Taha, Y. Deng, M. McBurney, D.J. Stewart, Ottawa, Canada,<br />
p.A3066<br />
1016 Endosomal Proteins p18 and Rab4 Are Differentially Regulated<br />
in Pulmonary Hypertension and COPD/Emphysema/H.<br />
Chichger, A. Vang, Q. Lu, G. Choudhary, E.O. Harrington,<br />
Cambridge, United Kingdom, p.A3067<br />
1017 Epigenetic Regulation of the Anti-Proliferative Transient<br />
Receptor Potential Melastatin 8 (TRPM8) Channels of<br />
Pulmonary Arterial Smooth Muscle Cells in Hypoxic<br />
Pulmonary Hypertension/J.S.K. Sham, O. Paudel, W.-Y. Tang,<br />
Baltimore, MD, p.A3068<br />
1018 Plasma Levels of Angiopoietin-2 in COPD: Effects of Smoking<br />
and Pulmonary Hypertension/V.I. Peinado, J. Garcia-Lucio, T.<br />
Paul, O. Tura, I. Blanco, J.A. Barbera, Barcelona, Spain, p.A3069<br />
1019 RASSF1A Regulates ROS-HIF Axis in Hypoxia Driven<br />
Pulmonary Hypertension/S. Dabral, C. Muecke, M. Schmoranzer,<br />
C. Valsarajan, A. Weitelmann, R. Savai, W. Seeger, R. Dammann,<br />
S.S. Pullamsetti, Bad Nauheim, Germany, p.A7808<br />
B28<br />
POSTER DISCUSSION SESSION<br />
ADVANCES IN STEM CELLS IN INJURY AND<br />
REPAIR FOR 2016<br />
9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />
Room 2014 (West Building, Level 2)<br />
Poster Viewing 9:00-9:45<br />
Discussion 9:45-11:00<br />
501 Human Bone Marrow Derived Mesenchymal Stem Cells and<br />
Their Released Microvesicles May Promote the Resolution of<br />
Acute Lung Injury in Mice in Part Through Inhibition of<br />
Multidrug Resistance-Associated Protein 1/Q. Hao, V. Gudapati,<br />
A. Monsel, H. Lim, J.-W. Lee, San Francisco, CA, p.A3070<br />
502 Generation of Purified Human Type II Alveolar Cells from<br />
Gene-Edited Pluripotent Stem Cells/A. Jacob, F. Hawkins, K.<br />
Benson, M. Serra, D.N. Kotton, Boston, MA, p.A3071<br />
503 Mesenchymal Stem Cells Drive Cell Repopulation In an In Vivo<br />
Model of Lung Regeneration/J. Sembrat, C. Caufield, N.<br />
Cardenes, R.R. Vanderpool, M. Bennewitz, S. Snovida, P. Sundd,<br />
M. Rojas, Pittsburgh, PA, p.A3072<br />
504 The Role of BMP Signaling in Deriving Endothelial Cells from<br />
Human Pluripotent Stem Cells/M. Jamal, N. Ruopp, N. Prasain,<br />
J.C. Jean, E.D. Austin, S. Majka, M. Yoder, D.N. Kotton, Boston,<br />
MA, p.A3073<br />
505 Human Umbilical Cord Mesenchymal Stromal/Stem Cells<br />
Reduce Lung Injury in Rodent E. Coli Pneumonia by<br />
Modulating Innate Immunity/M. Jerkic, A. Wolchuk, S. Dixon, G.<br />
Hogan, X. Xu, C. Masterson, G.F. Curley, J.G. Laffey, Toronto,<br />
Canada, p.A3074<br />
506 Bone Marrow Derived Human Mesenchymal Stem Cells<br />
Exposed to Pro-Inflammatory Cytokines Lose their<br />
Mesenchymal Marker Expression and Transform into Cells<br />
with Antigen Presenting Cell Gene Expression Patterns/M.<br />
Schwede, E.M. Wilfong, C.S. Calfee, M. Matthay, San Francisco,<br />
CA, p.A3075<br />
507 Characterizing Embryonic Stem Cell Derived Multipotent Lung<br />
Stem Cells/A. Kidiyoor, S. Murphy, A. Atala, Winston Salem, NC,<br />
p.A3076<br />
508 Human Bone Marrow-Derived Mesenchymal Stem Cells May<br />
Modulate TLR4 Signaling to Favorably Affect Human Alveolar<br />
Type II Cell Function in an In Vitro Model of Acute Lung<br />
Injury/E.M. Wilfong, M. Schwede, X. Fang, J.W. Lee, C.S. Calfee,<br />
M.A. Matthay, San Francisco, CA, p.A3077<br />
509 Patient-Derived Airway Stem Cells in Human Lung<br />
Bio-Engineering/S.E. Gilpin, J.M. Charest, L.F. Tapias, X. Ren, T.<br />
Wu, D.J. Mathisen, H.C. Ott, Boston, MA, p.A3078<br />
510 Mesenchymal Stem Cells Attenuate Hypoxia-Induced Pulmonary<br />
Epithelial Injury Via an NF-kB Dependent Paracrine Mechanism/N.<br />
Shologu, D. O’Toole, M. Scully, J. Laffey, Galway, Ireland, p.A3079<br />
511 Forkhead BOX F1 Is a Novel Regulator of Autotaxin and<br />
Modulates Migration of Human Lung-Resident Mesenchymal<br />
Stem Cells/P. Cao, N. Walker, S. Mazzoni, Y. Aoki, V. Lama, Ann<br />
Arbor, MI, p.A3080<br />
512 Modified Mesenchymal Stem Cells Using miRNA Transfection<br />
Could Modify Lung Fibrosis Progression/J. Sellares, L. Huleihel,<br />
N. Cardenes, D. Alvarez, K. Sakamoto, G. Yu, M. Kapetanaki, N.<br />
Kaminski, M. Rojas, Pittsburgh, PA, p.A3081<br />
513 Characteristics of Mesenchymal Stem Cells from Swine with<br />
and Without Acute Respiratory Distress Syndrome/B. Antebi,<br />
R.K. Montgomery, K.P. Walker, J.S. McDaniel, A.T. Dixon, A.P.<br />
Cap, L.C. Cancio, A.I. Batchinsky, Fort Sam Houston, TX, p.A3082<br />
514 Polyunsaturated Fatty Acids Potentiate the Effects of<br />
Mesenchymal Stromal Cells in Sepsis-Induced Acute<br />
Respiratory Distress Syndrome/J.D. Silva, J.Z. Kitoko, L.L.<br />
Castro, S.A.A. Trivelin, B.L. Diaz, P. Olsen, M.M. Morales, P.R.M.<br />
Rocco, Rio de Janeiro, Brazil, p.A3083<br />
515 Deficiencies in Mesenchymal Stem Cells from Idiopathic<br />
Pulmonary Fibrosis Patients Result in Lower Capacity to<br />
Protect the Lung from Injury/N. Cardenes, D. Alvarez, C. Corey,<br />
S. Wecht, J. Sembrat, V.S. Hanumanthu, M. Bueno, J.S. Nine, S.<br />
Shiva, M. Armanios, A.L. Mora, M. Rojas, Pittsburgh, PA, p.A3084<br />
516 A Role for Mesenchymal Cell Telomerase Reverse<br />
Transcriptase in Pulmonary Fibrosis/T. Liu, H. Yu, L. Ding, Z.<br />
Wu, F. Gonzalez De Los Santos, J. Liu, M. Ullenbruch, B. Hu, V.<br />
Martins, S.H. Phan, Ann Arbor, MI, p.A3085<br />
517 Dependence of Lung Epithelial Stem Cell Proliferation and<br />
Differentiation on Fibroblast-Specific FGF2 Signaling/M. Ozaki,<br />
A. Hegab, R. Guzy, D. Ornitz, T. Betsuyaku, Tokyo, Japan,<br />
p.A3086<br />
518 Alveolar Epithelial Type II Cell-Specific Deletion of Foxo1<br />
Results in Increased Stem/Progenitor Cell Proliferation In<br />
Vitro/Y. Yeragunta, D.R. Castillo, M. Rieger, J.M. Liebler, P.<br />
Flodby, B. Zhou, E.D. Crandall, Z. Borok, Los Angeles, CA,<br />
p.A3087<br />
ATS 2016 • San Francisco