Final Program
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TUESDAY • MAY 17 255<br />
615 Real-Time Imaging of Stretch-Induced ATP Release in Rat<br />
Pulmonary Epithelial Cells/J.J. Tan, E. Brochiero, R. Grygorczyk,<br />
Montreal, Canada, p.A4824<br />
616 The Role of Surfactant Dysfunction in Ventilator Induced Lung<br />
Injury Pathogenesis/B.J. Smith, S.A. Seong, G.S. Roy, J.H.T.<br />
Bates, Burlington, VT, p.A4825<br />
617 Linking Alveolar Epithelial Barrier Disruption to Function in<br />
Ventilator-Induced Lung Injury/K.L. Hamlington, C.M. Dunn, G.S.<br />
Roy, B.J. Smith, J.H.T. Bates, Burlington, VT, p.A4826<br />
618 Calculating an Injury Cost Function for Ventilator-Induced<br />
Lung Injury/J.H.T. Bates, B.J. Smith, K.L. Hamlington, G.B. Allen,<br />
Burlington, VT, p.A4827<br />
619 Pathophysiological Consequences of Lobar Unilateral Perfusion<br />
Block in a 8-Hour Large Animal Model of Ventilator Induced<br />
Lung Injury (VILI)/B. Cambiaghi, O. Moerer, G. Hahn, T. Mauri, E.A.<br />
Schulze Kalthoff, A.M. Pesenti, M. Quintel, Monza, Italy, p.A4828<br />
620 Effects of Ventilatory Settings on a Pendelluft Phenomenon<br />
During Mechanical Ventilation - A Lung Model Study/Y.<br />
Enokidani, A. Uchiyama, T. Yoshida, R. Abe, Y. Fujino, Osaka,<br />
Japan, p.A4829<br />
621 Activation of the ß2-Adrenergic Receptors on Monocytes<br />
Negatively Regulates Their Recruitment to the Injured Lung/L.<br />
Morales-Nebreda, R.B. Hamanaka, A. McQuattie-Pimentel, M. Chi,<br />
S. Soberanes, R. Nigdelioglu, T. Cho, A.V. Misharin, G.S.<br />
Budinger, G.M. Mutlu, Chicago, IL, p.A4830<br />
622 Inhibition of Prolyl Hydroxylase Attenuates Fas<br />
Ligand-Induced Apoptosis and Lung Injury in Mice/Y.<br />
Nagamine, K. Tojo, T. Yazawa, S. Takaki, Y. Baba, T. Goto, K.<br />
Kurahashi, Yokohama, Japan, p.A4831<br />
623 Impact of Ca2+ Signalling on Volume Regulated Anion Channel<br />
in A549 Alveolar Cells: Implication for Alveolar Fluid<br />
Clearance/O.O. Ponomarchuk, F. Boudreault, R. Grygorczyk, S.N.<br />
Orlov, Moscow, Russian Federation, p.A4832<br />
624 Optimal Variability Maintains Surfactant Metabolism During<br />
Ventilation of Preterm Sheep/E. Bartolak-Suki, J.J. Pillow, B.<br />
Suki, Boston, MA, p.A4833<br />
625 Variable Ventilation Minimizes Cyclical Overdistension and<br />
Pulmonary Inflammation in Lung-Healthy Anesthetized Rats/<br />
W. Zin, L. Camilo, M. Avila, L.F. Cruz, G. Motta-Ribeiro, M. Abreu,<br />
A. Cardozo, A. Carvalho, Rio de Janeiro, Brazil, p.A4834<br />
C31<br />
THEMATIC POSTER SESSION<br />
EXPERIMENTAL ASTHMA THERAPIES<br />
9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />
Viewing: Posters will be on display for entire session.<br />
Area D, Hall D (North Building, Lower Level)<br />
Discussion: 11:00-11:45: authors will be present for individual discussion<br />
11:45-12:45: authors will be present for discussion with assigned facilitators<br />
Facilitator:<br />
P371<br />
P372<br />
P373<br />
P374<br />
P375<br />
P376<br />
P377<br />
P378<br />
P379<br />
Facilitator:<br />
P380<br />
P381<br />
P382<br />
J.F. Alcorn, PhD, Pittsburgh, PA<br />
In Vivo Dual PI3kgd Inhibition in a Rat Model of Pulmonary<br />
Inflammation - Evidence of Local Therapeutic Activity/S.R.<br />
Blomqvist, T. Andreasson, S. Arlbrandt, P. Bold, K. Bjorhall, M.<br />
Brulls, P. Cygan, M. Karlsson, M. Mogemark, M. Perry, V. Morrison,<br />
C. Goodyear, K. Karabelas, M. Thomas, Molndal, Sweden, p.A4835<br />
Targeting the Immunological Drivers of Asthma with Inhaled<br />
Delivery of a JAK1 Inhibitor/M.C. Catley, A. Smailagic, M.<br />
Rhedin, N. Parker, M. Nilsson, A. Aurell Holmberg, R. Hendrickx, K.<br />
Johansson, Gothenburg, Sweden, p.A4836<br />
Depletion of Blood Eosinophils and Basophils After<br />
Administration of an Anti-CRTh2 Antibody in Cynomolgus<br />
Monkeys/T. Staton, F. Fuh, S. Klabunde, A. Reyes, T. Huang, Y.<br />
Shang, J. Payandeh, M. Matsumoto, I. Hotzel, H. Wang, J. Wang,<br />
K. Reif, H. Scheerens, South San francisco, CA, p.A4837<br />
TLR7/8 Ligand (Resiquimod, S28463) Protects Non-Human<br />
Primates from Ascaris Suum Extract Induced Model of Allergic<br />
Asthma/C. Kanagaratham, P. Camateros, J. Henri, F. Kopriva, M.<br />
Hajduch, D. Radzioch, Montreal, Canada, p.A4838<br />
Phosphoinositide-3 Kinase Inhibition in Th17-Dominant Allergic<br />
Airway Disease in Mice/M.L. Manni, M.E. Clay, K.J. McHugh, M.<br />
Salmon, J.K. Kolls, J.F. Alcorn, Pittsburgh, PA, p.A4839<br />
Leukotriene Receptor Blockade Decreases Mucin Production<br />
Triggered by Acute Ethanol Ingestion in Allergen-Sensitized<br />
Mice/B. Lussier, T. Hsieh, D. Remick, Boston, MA, p.A4840<br />
The Effect of Statin on Alternaria-Induced Asthma in Mice/T.<br />
Kamatani, M. Matsuzaka, K. Fukunaga, H. Kabata, T. Tanosaki, S.<br />
Kagawa, T. Mochimaru, R. Baba, K. Otsuka, S. Ueda, K. Tanaka,<br />
T. Betsuyaku, Tokyo, Japan, p.A4841<br />
Effects of Chronic Treatment with CAPE, a Specific NF Kappa-B<br />
Inhibitor, Compared to Rho Quinase Inhibitor or Corticosteroid<br />
on Airway Hyperresponsiveness in Mice with Chronic Allergic<br />
Pulmonary Inflammation/I.F. Tiberio, F.C.R. Souza, T.M. Santos,<br />
L.R. Aristoteles, R.F. Righetti, B. Saraiva-Romanholo, C.M. Prado,<br />
F.M.A. Costa, E.A. Leick, M.A. Martins, Brazil, p.A4842<br />
Acetaminophen Attenuates House Dust Mite Induced Allergic<br />
Airway Disease in Mice/G.J. Smith, R.S. Thrall, M.M. Cloutier,<br />
J.E. Manautou, J.B. Morris, Storrs, CT, p.A4843<br />
A. Haczku, MD, PhD, Davis, CA<br />
Electronic Cigarette Inhalation Promotes Inflammatory<br />
Cytokines Within the Airways and Systemic Inflammation in<br />
Mice/D. Mathew, J.H. Hwang, L.E. Crotty Alexander, San Diego,<br />
CA, p.A4844<br />
PGE2-Treated Macrophages Inhibit Development of Allergic<br />
Lung Inflammation in Mice/C. Draijer, C.E. Boorsma, C.<br />
Reker-Smit, E. Post, K. Poelstra, B.N. Melgert, Groningen,<br />
Netherlands, p.A4845<br />
Treatment with a Lysate of Helicobacter Pylori Prevents<br />
Allergic Airway Inflammation in Mice/Y. Van Wijck, S. De Kleijn,<br />
P.S. Hiemstra, A. Muller, H.H. Smits, C. Taube, Leiden,<br />
Netherlands, p.A4846<br />
TUESDAY MORNING<br />
ATS 2016 • San Francisco