Final Program

380 WEDNESDAY • MAY 18
P579
P580
D52
Enlarged, Hyperlucent Lung in a Five Month Old Male with
Multiple Congenital Anomalies/S.J. Khalfoun, B. Allen,
Columbus, OH, p.A7260
Hemorrhagic Complication of Intrapleural tPA in a One Year
Old Baby/S.Q. Ahmad, S. Agrawal, H. Lee, Brooklyn, NY, p.A7267
THEMATIC POSTER SESSION
MOLECULAR INSIGHT INTO PULMONARY
HYPERTENSION
9:00 a.m. - 3:30 p.m. MOSCONE CENTER
Viewing: Posters will be on display for entire session.
Area H, Hall D (North Building, Lower Level)
Discussion: 11:00-11:45: authors will be present for individual discussion
11:45-12:45: authors will be present for discussion with assigned facilitators
Facilitator:
P897
P898
P899
P900
P901
P902
P903
P904
E.A. Goncharova, PhD, Pittsburgh, PA
The Genome-Wide Landscape of Oxidative DNA Damage in
Human Vascular Endothelial Cells and Its Link to
Transcriptional Regulation in Hypoxia/V.M. Pastukh, J.T.
Roberts, G.C. Bardwell, G.M. Borchert, M.N. Gillespie, Mobile, AL,
p.A7268
Deficiency of TIMP-1 Is Protective in a Model of
Hypoxia-Induced Pulmonary Hypertension/C. Mallarino-Haeger,
A. Coronata, C.A. Owen, L. Fredenburgh, Boston, MA, p.A7269
Hemolysis Reduces HUWE1 Through PPARg Downregulation
in Sickle Cell Disease-Pulmonary Hypertension/B.-Y. Kang, J.M.
Kleinhenz, T.C. Murphy, R.L. Sutliff, D. Archer, C.M. Hart, Decatur,
GA, p.A7270
ASK1 Inhibition Prevents Hypoxia-Induced Pulmonary Artery
Fibroblast Activation and Paracrine Effects on Vascular Smooth
Muscle Cells/K.S. Wilson, K. Suveizdyte, J. Liles, G.R. Budas, A.
Peacock, D.J. Welsh, Glasgow, United Kingdom, p.A7271
Potential Role of DNA Methyltransferase 3A in Rat Models of
Pulmonary Hypertension/Y. Yan, X.-J. Wang, S.-H. Yang, S.-Q.
Li, Y. Liu, S.-S. Huang, J. Ye, Z.-C. Jing, Shanghai, China, p.A7272
Genetic Deletion of TWIK-2 Leads to Greater Depolarization of
Intralobar Pulmonary Vascular Smooth Muscle Cells,
Contributing to Pulmonary Hypertension in the TWIK-2
Knockout Mouse/L. Pandit, J.O. Reynolds, S.P. Marrelli, R.M.
Bryan, Houston, TX, p.A7273
Macrophage Depletion Results in Worsened Secondary
Pulmonary Hypertension and Improved Pulmonary
Fibrosis/A.J. Bryant, C. Fu, G. Brown, A. Biswas, V. Shenoy, M.
Katovich, E. Scott, Gainesville, FL, p.A7274
Protection Conferred by Y-Chromosome Against Pulmonary
Arterial Hypertension Is Not Due to Ddx3y Gene/S. Umar, M.
Barseghyan, A. Centala, N. Barakati, N. Motayagheni, A. Arnold, M.
Eghbali, Los Angeles, CA, p.A7275
P905
P906
P907
P908
Facilitator:
P909
P910
P911
P912
P913
P914
P915
P916
P917
P918
MicroRNA-214 Regulates Hypoxia-Mediated Pulmonary Artery
Smooth Muscle Cell Proliferation and Migration by Targeting
ARHGEF12/X.-Q. Xing, J. Yang, X.-W. Wu, Y.-L. Li, L.-Q. Liu, Y.
Xiao, Kunming, China, p.A7276
Oxidized Cardiolipin Causes Endothelial Specific Dysfunction
and Pulmonary Hypertension in an In Vivo and Ex Vivo
Model/J.R. Buland, K.J. Wasserloos, S. Hahn, V.E. Kagan, S.P.
Tofovic, A. Straub, B.R. Pitt, Pittsburgh, PA, p.A7277
Characterization of TGF-b and BMP Signaling in Rat Models of
PH/C.M. Happe, K. Kurakula, N. Rol, D. Bos, X. Sun, C. Van Der
Bruggen, A. Vonk Noordegraaf, M.-J. Goumans, F.S. De Man, H.J.
Bogaard, Amsterdam, Netherlands, p.A7278
MicroRNA-21 and PDCD4 Mediate Antiproliferative Effects of
PPAg in Hypoxia-Exposed Human Pulmonary Artery Smooth
Muscle Cells/D.E. Green, T.C. Murphy, C.M. Hart, Atlanta, GA,
p.A7279
P. Dorfmuller, PhD, MD, Le Plessis Robinson, France
Isolation and Characterization of Distal Pulmonary
Microvascular Endothelial Cell Clones from Wild-type and
TLR4 Deficient Mice/S. McMurtry, T. Stevens, S. Ofori-Acquah,
Mobile, AL, p.A7280
The Role of Macrophage Migration Inhibitory Factor on
Antioxidant Responses During Cigarette Smoke/M. Aladdin, L.
Varela, J. Fallica, P.M. Hassoun, R.L. Damico, Baltimore, MD, p.A7281
Beta Adrenergic Receptor Dysfunction in Pulmonary Arterial
Hypertension/M.K. Gupta, S. Ghosh, L.A. Mavrakis, S. Comhair,
S.C. Erzurum, S.V. Naga Prasad, Cleveland, OH, p.A7282
Aerobic Glycolysis Is Sufficient, but Not Necessary, for Rapid
Proliferation of Pulmonary Endothelial Cells/J.Y. Lee, T.
Stevens, Mobile, AL, p.A7283
A Comparison of the Pharmacological Profile of
Beraprost-315d with Esuberaprost and Beraprost: Role of the
Prostacyclin (IP) Receptor, PPARb and Nitric Oxide in Rat
Distal Pulmonary Arteries/L. Shen, C. Picken, K.R.B. Von
Kessler, P. Sista, L.H. Clapp, London, United Kingdom, p.A7284
Dysregulated Expression of Alarmins in the Pathology of
Pulmonary Hypertension/A. Petrovic, J.N. Schneider, M.
Wygrecka, O. Pak, E.E. Agha, N. Weissmann, S. Bellusci, D.
Kosanovic, R.T. Schermuly, Giessen, Germany, p.A7285
RP5063 Prevents Monocrotaline Induced Pulmonary Arterial
Hypertension in Rats/L. Bhat, D. Salvail, A. Bouchard, J.
Hawkinson, M. Cantillon, Santa Clara, CA, p.A7286
Lactate Activates Akt Through Calpain in Pulmonary Artery
Smooth Muscle Cells/L. Kovacs, Y. Su, Augusta, GA, p.A7287
A Scratch-Induced Interaction Between Extracellular Sodium
and Orai1 Is Critical for Endothelial Wound Healing/N. Xu, T.
Stevens, Mobile, AL, p.A7288
Involvement of HIV Infected and Cocaine Exposed Macrophage
Derived Extracellular Vesicles in Pulmonary Smooth Muscle
Hyperplasia/P.N. Dalvi, L. Christenson, S. Upadhya, A.
O’Brien-Ladner, N.K. Dhillon, Kansas City, KS, p.A7289
ATS 2016 • San Francisco