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TUESDAY • MAY 17 317<br />

C87<br />

BASIC<br />

PUBLIC ADVISORY ROUNDTABLE<br />

CME Credits Available: 2.0<br />

NEW INSIGHTS INTO THE GENETIC BASIS OF<br />

PEDIATRIC LUNG DISEASE<br />

Public Advisory Roundtable; Assembly on Pediatrics<br />

2:15 p.m. - 4:15 p.m. MOSCONE CENTER<br />

Room 3007/3009 (West Building, Level 3)<br />

Target Audience<br />

Physicians, basic and translational scientists, clinician-investigators, nurses,<br />

patients, and parents.<br />

Objectives<br />

At the conclusion of this session, the participant will be able to:<br />

• understand the genetics of interstitial lung diseases in neonates and children,<br />

and how this information is providing new insights into pathogenesis, improved<br />

diagnostic tests, and potential therapeutic targets;<br />

• appreciate the emerging genetics of primary ciliary dyskinesia and importance<br />

as a diagnostic approach, and understand genotype-phenotype relationships in<br />

this disease;<br />

• recognize the importance of genetics in the pathophysiology of cystic fibrosis<br />

lung disease, and how this knowledge has led to the development of precision<br />

medicine.<br />

The emergence of powerful, more affordable genomic technologies have advanced<br />

our knowledge of lung diseases at a rapid pace, providing greater insights into the<br />

genetics and pathophysiology of pulmonary diseases in children and adults. The<br />

progress made in genomics will increasingly translate into improved patient health,<br />

with improved diagnostic tests and personalized therapies. This session will highlight<br />

the progress made in genomics of lung diseases, focusing on the genetic and<br />

cellular bases of four childhood diseases, which will serve as a roadmap for other<br />

conditions.<br />

Chairing: G.R. Porta, BS, Mason, OH<br />

T.W. Ferkol, MD, St. Louis, MO<br />

2:15 Annual PAR Awards<br />

G.R. Porta, BS, Mason, OH<br />

2:30 Introduction<br />

T.W. Ferkol, MD, St. Louis, MO<br />

2:35 Neonatal Lung Diseases<br />

F.S. Cole, MD, St. Louis, MO<br />

3:00 Cystic Fibrosis<br />

G.R. Cutting, MD, Baltimore, MD<br />

3:25 Primary Ciliary Dyskinesia<br />

M. Knowles, MD, Chapel Hill, NC<br />

3:50 Childhood Interstitial Lung Diseases<br />

L.M. Nogee, MD, Baltimore, MD<br />

C88<br />

CLINICAL • TRANSLATIONAL<br />

SCIENTIFIC SYMPOSIUM<br />

CME Credits Available: 2.0<br />

VIRAL COMMUNITY-ACQUIRED PNEUMONIA<br />

Assemblies on Microbiology, Tuberculosis and Pulmonary Infections;<br />

Clinical Problems; Critical Care; Pediatrics<br />

2:15 p.m. - 4:15 p.m. MOSCONE CENTER<br />

Room 3016/3018 (West Building, Level 3)<br />

Target Audience<br />

Pulmonologists, critical care specialists, pediatricians, scientists, hospital<br />

administrators, medical providers, trainees, fellows, and advanced practice<br />

providers.<br />

Objectives<br />

At the conclusion of this session, the participant will be able to:<br />

• understand and learn about recent epidemiological data on respiratory viruses as<br />

etiology of community acquired pneumonia;<br />

• learn new diagnostics tools to detect viral infection, including understanding the utility of<br />

procalcitonin in clinical medicine;<br />

• understand how to integrate new information on respiratory viruses into clinical practice.<br />

This session will provide the learner a comprehensive overview on how respiratory viruses<br />

contribute to current causes of community acquired pneumonia (CAP) and acute lung<br />

injuries in the ICU especially in the setting of the increasing use of genetic-based diagnostic<br />

approaches to detect viruses. Speakers in this symposium will highlight the current<br />

epidemiology of viral CAP and review the existing diagnostics of viral CAP including a<br />

pro/con debate on the role of procalcitonin in viral pneumonia. The role of viral pneumonia as<br />

cause of ARDS, and how RSV contributes to the disease in children and the elderly will be<br />

explored. And finally, given the increased use of molecular diagnostics to detect respiratory<br />

viruses, there will be a timely and careful discussion on what to do with a positive respiratory<br />

virus panel, including an analysis of whether rhinovirus ever causes pneumonia. These<br />

series of talks will update the audience on the recent information on viral pneumonia in<br />

clinical medicine with the goal of improving not only understanding of this topic but better<br />

implementation of current knowledge on viral pneumonia into practice.<br />

Chairing: C.S. Dela Cruz, MD, PhD, New Haven, CT<br />

R.D. Shah, MD, Chicago, IL<br />

2:15 Epidemiology of Viral CAP<br />

W. Self, MD, MPH, Nashville, TN<br />

2:35 Pro/Con Debate: Procalcitonin for Viral Pneumonia (Con)<br />

G.W. Waterer, MBBS, PhD, MBA, Perth, Australia<br />

2:50 Pro/Con Debate: Procalcitonin for Viral Pneumonia (Pro)<br />

T. File, MD, Akron, OH<br />

3:05 RSV in the Young and Old Patients<br />

J. Devincenzo, MD, Memphis, TN<br />

3:25 Viral Pneumonia and ARDS: A Lethal Combination<br />

J.E. Chastre, MD, Paris, France<br />

3:45 What to Do with a Positive Respiratory Virus Panel (RVP)?<br />

R.G. Wunderink, MD, Chicago, IL<br />

4:05 Discussion<br />

C.S. Dela Cruz, MD, PhD, New Haven, CT<br />

There will be a 5-minute discussion after each talk.<br />

TUESDAY AFTERNOON<br />

ATS 2016 • San Francisco

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