Final Program
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TUESDAY • MAY 17 317<br />
C87<br />
BASIC<br />
PUBLIC ADVISORY ROUNDTABLE<br />
CME Credits Available: 2.0<br />
NEW INSIGHTS INTO THE GENETIC BASIS OF<br />
PEDIATRIC LUNG DISEASE<br />
Public Advisory Roundtable; Assembly on Pediatrics<br />
2:15 p.m. - 4:15 p.m. MOSCONE CENTER<br />
Room 3007/3009 (West Building, Level 3)<br />
Target Audience<br />
Physicians, basic and translational scientists, clinician-investigators, nurses,<br />
patients, and parents.<br />
Objectives<br />
At the conclusion of this session, the participant will be able to:<br />
• understand the genetics of interstitial lung diseases in neonates and children,<br />
and how this information is providing new insights into pathogenesis, improved<br />
diagnostic tests, and potential therapeutic targets;<br />
• appreciate the emerging genetics of primary ciliary dyskinesia and importance<br />
as a diagnostic approach, and understand genotype-phenotype relationships in<br />
this disease;<br />
• recognize the importance of genetics in the pathophysiology of cystic fibrosis<br />
lung disease, and how this knowledge has led to the development of precision<br />
medicine.<br />
The emergence of powerful, more affordable genomic technologies have advanced<br />
our knowledge of lung diseases at a rapid pace, providing greater insights into the<br />
genetics and pathophysiology of pulmonary diseases in children and adults. The<br />
progress made in genomics will increasingly translate into improved patient health,<br />
with improved diagnostic tests and personalized therapies. This session will highlight<br />
the progress made in genomics of lung diseases, focusing on the genetic and<br />
cellular bases of four childhood diseases, which will serve as a roadmap for other<br />
conditions.<br />
Chairing: G.R. Porta, BS, Mason, OH<br />
T.W. Ferkol, MD, St. Louis, MO<br />
2:15 Annual PAR Awards<br />
G.R. Porta, BS, Mason, OH<br />
2:30 Introduction<br />
T.W. Ferkol, MD, St. Louis, MO<br />
2:35 Neonatal Lung Diseases<br />
F.S. Cole, MD, St. Louis, MO<br />
3:00 Cystic Fibrosis<br />
G.R. Cutting, MD, Baltimore, MD<br />
3:25 Primary Ciliary Dyskinesia<br />
M. Knowles, MD, Chapel Hill, NC<br />
3:50 Childhood Interstitial Lung Diseases<br />
L.M. Nogee, MD, Baltimore, MD<br />
C88<br />
CLINICAL • TRANSLATIONAL<br />
SCIENTIFIC SYMPOSIUM<br />
CME Credits Available: 2.0<br />
VIRAL COMMUNITY-ACQUIRED PNEUMONIA<br />
Assemblies on Microbiology, Tuberculosis and Pulmonary Infections;<br />
Clinical Problems; Critical Care; Pediatrics<br />
2:15 p.m. - 4:15 p.m. MOSCONE CENTER<br />
Room 3016/3018 (West Building, Level 3)<br />
Target Audience<br />
Pulmonologists, critical care specialists, pediatricians, scientists, hospital<br />
administrators, medical providers, trainees, fellows, and advanced practice<br />
providers.<br />
Objectives<br />
At the conclusion of this session, the participant will be able to:<br />
• understand and learn about recent epidemiological data on respiratory viruses as<br />
etiology of community acquired pneumonia;<br />
• learn new diagnostics tools to detect viral infection, including understanding the utility of<br />
procalcitonin in clinical medicine;<br />
• understand how to integrate new information on respiratory viruses into clinical practice.<br />
This session will provide the learner a comprehensive overview on how respiratory viruses<br />
contribute to current causes of community acquired pneumonia (CAP) and acute lung<br />
injuries in the ICU especially in the setting of the increasing use of genetic-based diagnostic<br />
approaches to detect viruses. Speakers in this symposium will highlight the current<br />
epidemiology of viral CAP and review the existing diagnostics of viral CAP including a<br />
pro/con debate on the role of procalcitonin in viral pneumonia. The role of viral pneumonia as<br />
cause of ARDS, and how RSV contributes to the disease in children and the elderly will be<br />
explored. And finally, given the increased use of molecular diagnostics to detect respiratory<br />
viruses, there will be a timely and careful discussion on what to do with a positive respiratory<br />
virus panel, including an analysis of whether rhinovirus ever causes pneumonia. These<br />
series of talks will update the audience on the recent information on viral pneumonia in<br />
clinical medicine with the goal of improving not only understanding of this topic but better<br />
implementation of current knowledge on viral pneumonia into practice.<br />
Chairing: C.S. Dela Cruz, MD, PhD, New Haven, CT<br />
R.D. Shah, MD, Chicago, IL<br />
2:15 Epidemiology of Viral CAP<br />
W. Self, MD, MPH, Nashville, TN<br />
2:35 Pro/Con Debate: Procalcitonin for Viral Pneumonia (Con)<br />
G.W. Waterer, MBBS, PhD, MBA, Perth, Australia<br />
2:50 Pro/Con Debate: Procalcitonin for Viral Pneumonia (Pro)<br />
T. File, MD, Akron, OH<br />
3:05 RSV in the Young and Old Patients<br />
J. Devincenzo, MD, Memphis, TN<br />
3:25 Viral Pneumonia and ARDS: A Lethal Combination<br />
J.E. Chastre, MD, Paris, France<br />
3:45 What to Do with a Positive Respiratory Virus Panel (RVP)?<br />
R.G. Wunderink, MD, Chicago, IL<br />
4:05 Discussion<br />
C.S. Dela Cruz, MD, PhD, New Haven, CT<br />
There will be a 5-minute discussion after each talk.<br />
TUESDAY AFTERNOON<br />
ATS 2016 • San Francisco