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Membrane and Desalination Technologies - TCE Moodle Website

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Gas-Sparged Ultrafiltration: Recent Trends, Applications <strong>and</strong> Future Challenges 675<br />

Fig. 16.2. Gas–liquid two-phase flow patterns (adapted from Hewitt <strong>and</strong> Hall-Taylor (32)).<br />

membranes, slug flow is preferred. Figure 16.3 shows various membrane/bubbling arrangements<br />

(1) (Fig. 16.3). A comparison of flux enhancement by using different membrane<br />

modules, operating conditions <strong>and</strong> test media are summarized in Table 16.1.<br />

4.1. Gas-Sparging in Tubular <strong>Membrane</strong> Modules<br />

Effect of gas sparging in tubular membrane modules has been extensively studied by many<br />

researchers. Gas sparging has been examined over a wide range of operating conditions (such<br />

as TMP, gas flow rate, <strong>and</strong> feed concentration) <strong>and</strong> using different test media such as<br />

dextrans, therapeutic proteins (e.g. IgG, human serum albumin), other proteins (such as<br />

lysozyme, bovine serum albumin) <strong>and</strong> cells (yeast) (1, 7, 12, 13). The effect of membrane<br />

orientation has also been studied.<br />

The use of gas sparging for permeate flux enhancement was first reported by Cui (12). He<br />

used a vertical tubular membrane module (12.7 mm i.d., PVDF, MWCO: 100 kDa) with<br />

colored dextran solution (MW: 87 kDa) as the test media. Figure 16.4 shows that gas sparging<br />

even at a low gas flow rate (ratio Vg/Vl ¼ 0.07) increased the flux significantly. However,<br />

higher gas flow rates did not seem to increase permeate flux any further. These initial<br />

observations by Cui (12) were later confirmed by many researchers (13, 27, 33–37). The<br />

flux enhancement was found to depend on the type of membrane module <strong>and</strong> its orientation, <strong>and</strong><br />

operating parameters like TMP, feed concentration, gas flow rate, liquid cross-flow velocity.

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