Health Risks of Ionizing Radiation: - Clark University

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Not available Elevated SMRs for cancers of the digestive system (1.3, 0.9-1.9), stomach (1.7, 0.7-3.4) and larynx (4.5, 1.4-10.4) Cohort study of mortality in 995 workers at the Linde Air Products Company 1943-1949 Dupree et al. 1987 ERR for kidney cancer 10.5/Sv (90% CI 0.6-57.4) Mean cumulative dose 47.8 mSv Cohort study of mortality in 2,514 workers at Mallinckrodt Chemical Works 1942-1966 Dupree-Ellis et al. 2000 Significant dose-response trends for all cancer (ERR 1.5/Sv, 0.2-3.5) and lung cancer (ERR 1.7/Sv, 0.0-4.9) with significant differences among facilities 3 Mean dose ~17 mSv among exposed workers Cohort study of mortality in 106,020 Oak Ridge workers 1945-1985 Frome et al 1997 Significant dose-response trends for multiple myeloma, Hodgkin’s disease, and cancers of the liver and pancreas Mean external dose 23 mSv Cohort study of cancer mortality in 36,971 monitored Hanford employees 1945-1986 Gilbert et al. 1993 Significant dose-response trends for multiple myeloma, female genital cancer and all female cancers Mean external dose 23 mSv Cohort study of cancer mortality in 36,235 monitored Hanford employees 1945-1981 Gilbert et al. 1989 ERR ~3.8/Sv for all ages and ~20/Sv for exposures after age 58, no compelling evidence for a supralinear doseresponse curve Mean external dose 23 mSv Reanalysis of cancer mortality in 27,395 monitored Hanford employees 1945-1986 Kneale and Stewart 1993 Radiation Workers 91 Data appeared to fit a supralinear dose-response curve (but see Kneale and Stewart 1993) Mean external dose ~30 mSv Cohort study of cancer mortality in 27,962 Hanford workers 1944-1977 Kneale et al. 1981
92 Radiation Workers Not available No evidence of risk Case-control study of melanoma incidence in LANL workers 1969-1978 Acquavella et al. 1983 Not available Elevated SMRs for cancers of the lung, prostate, CNS, and kidney. Cohort study of mortality in 8,116 Y-12 workers 1947-1990 Loomis and Wolf 1996 Data suggest that younger (45) workers may have increased sensitivity to low level exposure and that the induced cancers have long latent periods Mean external dose of 11 mSv among monitored deceased workers Analysis of cancer mortality in 24,939 Hanford workers 1944- 1972 Mancuso et al. 1977 Significant association between dose and bladder cancer incidence with a 20-year lag. Overall ERR for cancer incidence with a 10-yr lag –0.9/Sv (
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Health Risks of Ionizing Radiation:
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Contents List of Tables ...........
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Contents iii Rocky Flats ..........
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Contents v APPENDIX A .............
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List of Figures Figure 1-1 Average
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We are indeed grateful to those who
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2 Introduction 1.2 A brief history
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4 Introduction Figure 1-2. The evol
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6 Introduction Figure 1-5(a). Alpha
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8 Introduction In epidemiological s
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10 Introduction precision to detect
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12 Introduction available informati
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14 Background Radiation Figure 2-1.
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16 Background Radiation Figure 2-3.
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18 Background Radiation
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20 Medical Exposures Fi
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22 Medical Exposures
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24 Medical Exposures with national
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26 Medical Exposures localized expo
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28 Medical Exposures (2.1-28.7). Th
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30 Medical Exposures posed 2.69 tim
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32 Medical Exposures with diagnosti
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34 Medical Exposures Table 3-1. Stu
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Page 51 and 52: 40 Medical Exposures
Page 53 and 54: 42 Medical Exposures
Page 55 and 56: 44 Atomic Bomb Survivors Figure 4-2
Page 57 and 58: 46 Atomic Bomb Survivors
Page 59 and 60: 48 Atomic Bomb Survivors approximat
Page 61 and 62: 50 Atomic Bomb Survivors (ALL), acu
Page 63 and 64: 52 Atomic Bomb Survivors of the 8 t
Page 69 and 70: 5 Nuclear Weapons Testing Over 500
Page 71 and 72: 60 Nuclear Weapons Testing by disti
Page 73 and 74: 62 Nuclear Weapons Testing Figure 5
Page 75 and 76: 64 Nuclear Weapons Testing near the
Page 77 and 78: 66 Nuclear Weapons Testing
Page 79 and 80: 68 Nuclear Weapons Testing
Page 81 and 82: 6 RADIATION WORKERS Introduction Th
Page 83 and 84: 72 Radiation Workers • 50 rem (0.
Page 85 and 86: 74 Radiation Workers work, reports
Page 87 and 88: 76 Radiation Workers Figure 6-5. A
Page 89 and 90: 78 Radiation Workers Figure 6-8. To
Page 93 and 94: 82 Radiation Workers Feed Material
Page 95 and 96: 84 Radiation Workers by Beral et al
Page 99 and 100: 88 Radiation Workers Table 6-1. Leu
Page 101: 90 Radiation Workers No
Page 105 and 106: 94 Radiation Workers S
Page 107 and 108: 96 Radiation Workers ERR estim
Page 109 and 110: 98 Mayak Workers Table 1. Dose (Gy)
Page 111 and 112: 100 Mayak Workers workers at the ra
Page 113 and 114: 102 Mayak Workers
Page 115 and 116: 104 Uranium Miners enrichment facil
Page 117 and 118: 106 Uranium Miners Samet et al. (19
Page 119: 108 Uranium Miners were selected 12
Page 122 and 123: Uranium Miners 111
Page 124 and 125: 9 RADIATION EXPOSURE IN FLIGHT The
Page 126 and 127: DNA damage (a chemical change in DN
Page 128 and 129: 10 PRECONCEPTION EXPOSURES Several
Page 130 and 131: of risk in the lowest dose groups,
Page 132 and 133: found elevated solid cancer risk wi
Page 134 and 135: preconception doses between 2.5 and
Page 136 and 137: Table 10-1. Preconception irradiati
Page 138 and 139: Preconception Exposures 127
Page 140 and 141: Tracheoesophageal fistula and conge
Page 142 and 143: cancer were both associated with th
Page 144 and 145: 0.10-4.71) while respiratory system
Page 146 and 147: elationship was not significant for
Page 148 and 149: times higher than in less-contamina
Page 150 and 151: Nuclear Power Accidents 139
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Nuclear Power Accidents 141
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Nuclear Power Accidents 143
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12 COMMUNITIES NEAR NUCLEAR FACILIT
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levels (this could not in itself be
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Figure 12-3. Native Americans from
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of leukemia was measured over a lar
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(RR 1.06; 1.00-1.11) and risks of s
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more that we can say about this app
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Communities Near Nuclear Facilities
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54 observed vs. 46.1 expected death
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13 DISCUSSION Our intention in crea
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myeloid leukemia) was significantly
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0.1-3.5 WLM; this is roughly equiva
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adon (Lubin et al. 1997). These res
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Leukemia Leukemia, a general term t
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vical cancer. The doses to these pa
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England have found it convenient to
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Thyroid disease Thyroid cancer is a
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1986 through 1995. These workers sh
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dence of this disease includes elev
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Analysis of preconception exposure
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Paternal age, education, drinking O
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Gardner et al. 1990 Employed at Sel
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we consider this group of a few hun
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Leukemia risk (excluding CLL) among
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Glossary of Terms for Epidemiology
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Glossary 199 Beta radiation: Stream
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Dosimetry: Measurement or estimatio
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Glossary 203 Hypothyroidism: The cl
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Glossary 205 Metastasis: 1. Movemen
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Glossary 207 waves, ultra violet (U
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Glossary 209 Thyroid Disease: disea
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Bibliography ATSDR. Public Health A
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Bhatia S, Sklar C. Second cancers i
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Bibliography 215 Cavallo D, Tomao P
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Bibliography 217 Department of Ener
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Bibliography 219 Gardner MJ, Hall A
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Haldorsen T, Reitan JB, Tveten U. C
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Bibliography 223 Howe GR, Nair R, N
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of Mayak, A comparison of numerical
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Bibliography 227 Laird NM. Thyroid
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control population. International J
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Bibliography 231 Neel JV, Schull WJ
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2003.160:381-407. Bibliography 233
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Bibliography 235 Saccomanno G, Auer
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Bibliography 237 analysis of cancer
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Bibliography 239 Tokarskaya ZB, Sco
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Journal of Epidemiology 1987.125(2)
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Actinium, 84 Acute lymphocytic leuk
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and Nevada Test Site, 60-61, 62 nuc
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Hashimoto’s thyroiditis, 185 Heal
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studies, 101-2 Medical exposure, 19
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(RERF), 43 Radiation Exposure Compe
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Viruses, 118, 154, 193 West Germany
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