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Health Risks of Ionizing Radiation: - Clark University

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iv Contents<br />

9. RADIATION EXPOSURE IN FLIGHT .........................................................................113<br />

9.1 Epidemiological studies ............................................................................................ 113<br />

9.2 Cell studies ............................................................................................................... 113<br />

9.3 Discussion ................................................................................................................. 113<br />

10. PRECONCEPTION EXPOSURES .................................................................................117<br />

10.1 The Seascale leukemia cluster and the Gardner hypothesis ..................................... 117<br />

10.2 Further studies <strong>of</strong> the Gardner hypothesis in the UK ............................................... 118<br />

10.3 Preconception exposure in other settings ................................................................. 119<br />

10.4 Solid cancers in association with preconception expsoures ..................................... 120<br />

10.5 Adverse birth outcomes in association with preconception exposures .................... 121<br />

10.6 Cell studies ............................................................................................................... 121<br />

10.7 Animal evidence ....................................................................................................... 122<br />

10.8 Discussion ................................................................................................................. 122<br />

11. NUCLEAR POWER ACCIDENTS ................................................................................ 130<br />

11.1 Three Mile Island ..................................................................................................... 130<br />

11.2 Chernobyl ................................................................................................................. 131<br />

11.2.1 Dose reconstruction for Chernobyl downwinders .................................................. 131<br />

11.2.2 Chernobyl emergency workers ................................................................................ 132<br />

11.2.3 Childhood thyroid cancer ................................................................................... 133<br />

11.2.4 Childhood leukemia ........................................................................................... 135<br />

11.2.5 Non-cancer effects in children ........................................................................... 136<br />

11.2.6 Chernobyl discussion ......................................................................................... 137<br />

12. COMMUNITIES NEAR NUCLEAR FACILITIES ..................................................... 145<br />

12.1 Introduction .............................................................................................................. 145<br />

Types <strong>of</strong> studies .................................................................................................. 146<br />

12.2 US studies ................................................................................................................. 146<br />

Hanford .............................................................................................................. 146<br />

Other US facilities .............................................................................................. 147<br />

Multi-site studies in the US ................................................................................ 148<br />

12.3 UK studies ................................................................................................................ 148<br />

Sellafield ............................................................................................................ 149<br />

Dounreay ............................................................................................................ 149<br />

Other UK facilities and multi-site studies .......................................................... 150<br />

12.4 Nuclear facilities outside the US and UK ................................................................. 151<br />

12.5 Discussion ................................................................................................................. 153<br />

13. DISCUSSION .................................................................................................................... 167<br />

The idea <strong>of</strong> a threshold dose .............................................................................. 167<br />

Positive resluts at low doses .............................................................................. 167<br />

Uncertainty and judgement ................................................................................ 171<br />

Synthesis <strong>of</strong> information .................................................................................... 171<br />

What if there is a threshold dose? ...................................................................... 173<br />

Conclusion ......................................................................................................... 174

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