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Health Risks of Ionizing Radiation: - Clark University

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110 Uranium Miners<br />

<br />

<br />

>120 WLM 70 observed deaths, 11.71 expected<br />

Cohort study <strong>of</strong> respiratory<br />

cancer in 4,146 U.S. miners<br />

1950-1960<br />

Archer et<br />

al. 1973<br />

RR 28.6 (13.2-61.7) for uranium miners compared<br />

to non-uranium miners<br />

Mean cumulative exposure<br />

1635 WLM (1969-83) and<br />

1292 WLM (1984-1993)<br />

Cohort study <strong>of</strong> lung cancer<br />

mortality in 757 Navajo miners<br />

1969-1993<br />

Gilliland<br />

et al.<br />

2000a<br />

0->1,450 WLM RR 29.2 (5.1-167.2) for miners with 1,450 WLM<br />

exposure compared to those with less than 80<br />

WLM. Inverse dose-rate effect especially at low<br />

doses. Non-smoker uranium miners’ excess risk is<br />

3 times that <strong>of</strong> smokers for lung cancer<br />

Cohort study <strong>of</strong> lung cancer<br />

mortality in 2,209 US miners<br />

1956-1996<br />

Gilliland<br />

et al.<br />

2000b<br />

ERR ~0.035/WLM (0.027-0.043)<br />

Mean cumulative exposure<br />

2.8 WLM (surface<br />

workers) and 16.6 WLM<br />

(underground workers)<br />

Cohort study <strong>of</strong> lung cancer<br />

mortality in 8,487 uranium<br />

mine workers in Saskatchewan,<br />

Canada 1966-1980<br />

Howe et<br />

al. 1986<br />

ERR 0.0027/WLM (0.0011-0.0043). Higher risk<br />

coefficients at lower levels <strong>of</strong> cumulative<br />

exposure 1<br />

Mean cumulative<br />

exposure 183 WLM<br />

Cohort study <strong>of</strong> lung cancer<br />

mortality in 2,103 uranium<br />

mine workers in the Northwest<br />

Territories, Canada 1942-1960<br />

Howe et<br />

al. 1987<br />

1 The estimated ERR was 0.65, 0.01, 0.003, 0.002 and 0.003/WLM at 0-4, 5-399, 400-799, 800-1,599, and >1,600 WLM, respectively

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