Health Risks of Ionizing Radiation: - Clark University

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Leukemia risk (excluding CLL) among the Techa River cohort appeared to be linear with dose, with an ERR of 6.5/Gy (1.8-24). This is higher than the estimate from the recent analysis of nuclear workers (1.9/Sv,
Acronyms & Abbreviations Acronyms AEA Atomic Energy Authority ALL acute lymphocytic leukemia AML acute myelogenous leukemia BEIR Committee on the Biological Effects of Ionizing Radiation CDC Centers for Disease Control and Prevention CEDE committed effective dose equivalent CLL chronic lymphocytic leukemia CML chronic myeloid leukemia CNS central nervous system CT computed tomography, or CAT scan LNHL leukemia and non-Hodgkin’s lymphoma DOE Department of Energy AEC Atomic Energy Commission ABCC Atomic Bomb Causality Commission RERF Radiation Effects Research Foundation NTS Nevada Test Site STS Semipalatinsk Test Site SRS Savannah River Site SMR standardized mortality ratio SIR standardized incidence ratio RR relative risk DDE deep dose equivalent DNA deoxyribo nucleic acid DOT Department of Transportation DREF dose rate effectiveness factor EAR excess absolute risk ECRR European Committee on Radiation Risk EPA Environmental Protection Agency ERDA Energy Research and Development Administration ERR excess relative risk FDA Food and Drug Administration HTDS Hanford Thyroid Disease Study ICRP International Commission on Radiological Protection LDE lens dose equivalent LET linear energy transfer LLNL Lawrence Livermore National Laboratory LSS Life Span Study NAS National Academy of Sciences NCHS National Center for Health Statistics NCI National Cancer Institute NCRP National Council on Radiation Protection and Measurements NRC Nuclear Regulatory Commission NRPB UK National Radiological Protection Board NRRW National Registry for Radiation Workers OPCS Office of Population Censuses and Surveys ORNL Oak Ridge National Laboratory OSCC Oxford Survey of Childhood Cancers OSHA Occupational Safety and Health Administration PPI paternal preconception irradiation RAC Radiological Assessments Corporation RBE relative biological effectiveness RNMDR Russian National Medical and Dosimetric Registry RPG radiation protection guides SDE shallow dose equivalent TEDE total effective dose equivalent TMI Three Mile Island TSH thyroid-stimulating hormone UK United Kingdom UNSCEAR United Nations Scientific Committee on the Effects of Atomic Radiation WL Working Level WLM Working Level Month 196 Abbreviations Bq Becquerel Gy Gray Km Kilometer Rad radiation absorbed dose Rem Roentgen equivalent in man Sv Sievert
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Health Risks of Ionizing Radiation:
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Contents List of Tables ...........
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Contents iii Rocky Flats ..........
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Contents v APPENDIX A .............
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List of Figures Figure 1-1 Average
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We are indeed grateful to those who
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2 Introduction 1.2 A brief history
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4 Introduction Figure 1-2. The evol
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6 Introduction Figure 1-5(a). Alpha
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8 Introduction In epidemiological s
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10 Introduction precision to detect
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12 Introduction available informati
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14 Background Radiation Figure 2-1.
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16 Background Radiation Figure 2-3.
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18 Background Radiation
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20 Medical Exposures Fi
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22 Medical Exposures
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24 Medical Exposures with national
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26 Medical Exposures localized expo
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28 Medical Exposures (2.1-28.7). Th
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30 Medical Exposures posed 2.69 tim
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32 Medical Exposures with diagnosti
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34 Medical Exposures Table 3-1. Stu
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44 Atomic Bomb Survivors Figure 4-2
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46 Atomic Bomb Survivors
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48 Atomic Bomb Survivors approximat
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50 Atomic Bomb Survivors (ALL), acu
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52 Atomic Bomb Survivors of the 8 t
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5 Nuclear Weapons Testing Over 500
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60 Nuclear Weapons Testing by disti
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62 Nuclear Weapons Testing Figure 5
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64 Nuclear Weapons Testing near the
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66 Nuclear Weapons Testing
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68 Nuclear Weapons Testing
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6 RADIATION WORKERS Introduction Th
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72 Radiation Workers • 50 rem (0.
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74 Radiation Workers work, reports
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76 Radiation Workers Figure 6-5. A
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78 Radiation Workers Figure 6-8. To
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82 Radiation Workers Feed Material
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84 Radiation Workers by Beral et al
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88 Radiation Workers Table 6-1. Leu
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90 Radiation Workers No
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92 Radiation Workers N
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94 Radiation Workers S
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96 Radiation Workers ERR estim
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98 Mayak Workers Table 1. Dose (Gy)
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100 Mayak Workers workers at the ra
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102 Mayak Workers
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104 Uranium Miners enrichment facil
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106 Uranium Miners Samet et al. (19
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108 Uranium Miners were selected 12
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Uranium Miners 111
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9 RADIATION EXPOSURE IN FLIGHT The
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DNA damage (a chemical change in DN
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10 PRECONCEPTION EXPOSURES Several
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of risk in the lowest dose groups,
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found elevated solid cancer risk wi
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preconception doses between 2.5 and
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Table 10-1. Preconception irradiati
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Preconception Exposures 127
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Tracheoesophageal fistula and conge
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cancer were both associated with th
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0.10-4.71) while respiratory system
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elationship was not significant for
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times higher than in less-contamina
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Nuclear Power Accidents 139
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Page 156 and 157: 12 COMMUNITIES NEAR NUCLEAR FACILIT
Page 158 and 159: levels (this could not in itself be
Page 160 and 161: Figure 12-3. Native Americans from
Page 162 and 163: of leukemia was measured over a lar
Page 164 and 165: (RR 1.06; 1.00-1.11) and risks of s
Page 166 and 167: more that we can say about this app
Page 168 and 169: Communities Near Nuclear Facilities
Page 176 and 177: 54 observed vs. 46.1 expected death
Page 178 and 179: 13 DISCUSSION Our intention in crea
Page 180 and 181: myeloid leukemia) was significantly
Page 182 and 183: 0.1-3.5 WLM; this is roughly equiva
Page 184 and 185: adon (Lubin et al. 1997). These res
Page 186 and 187: Leukemia Leukemia, a general term t
Page 188 and 189: vical cancer. The doses to these pa
Page 190 and 191: England have found it convenient to
Page 192 and 193: Thyroid disease Thyroid cancer is a
Page 194 and 195: 1986 through 1995. These workers sh
Page 196 and 197: dence of this disease includes elev
Page 198 and 199: Analysis of preconception exposure
Page 200 and 201: Paternal age, education, drinking O
Page 202 and 203: Gardner et al. 1990 Employed at Sel
Page 204 and 205: we consider this group of a few hun
Page 208 and 209: Glossary of Terms for Epidemiology
Page 210 and 211: Glossary 199 Beta radiation: Stream
Page 212 and 213: Dosimetry: Measurement or estimatio
Page 214 and 215: Glossary 203 Hypothyroidism: The cl
Page 216 and 217: Glossary 205 Metastasis: 1. Movemen
Page 218 and 219: Glossary 207 waves, ultra violet (U
Page 220 and 221: Glossary 209 Thyroid Disease: disea
Page 222 and 223: Bibliography ATSDR. Public Health A
Page 224 and 225: Bhatia S, Sklar C. Second cancers i
Page 226 and 227: Bibliography 215 Cavallo D, Tomao P
Page 228 and 229: Bibliography 217 Department of Ener
Page 230 and 231: Bibliography 219 Gardner MJ, Hall A
Page 232 and 233: Haldorsen T, Reitan JB, Tveten U. C
Page 234 and 235: Bibliography 223 Howe GR, Nair R, N
Page 236 and 237: of Mayak, A comparison of numerical
Page 238 and 239: Bibliography 227 Laird NM. Thyroid
Page 240 and 241: control population. International J
Page 242 and 243: Bibliography 231 Neel JV, Schull WJ
Page 244 and 245: 2003.160:381-407. Bibliography 233
Page 246 and 247: Bibliography 235 Saccomanno G, Auer
Page 248 and 249: Bibliography 237 analysis of cancer
Page 250 and 251: Bibliography 239 Tokarskaya ZB, Sco
Page 252 and 253: Journal of Epidemiology 1987.125(2)
Page 254 and 255: Actinium, 84 Acute lymphocytic leuk
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and Nevada Test Site, 60-61, 62 nuc
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Hashimoto’s thyroiditis, 185 Heal
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studies, 101-2 Medical exposure, 19
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(RERF), 43 Radiation Exposure Compe
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Viruses, 118, 154, 193 West Germany
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