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Health Risks of Ionizing Radiation: - Clark University

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Figure 3-2. In the 1950s the panoramic X-ray machine was<br />

invented to take a picture <strong>of</strong> the whole mouth with just<br />

one exposure (www.nist.gov/public_affairs/licweb/dental.<br />

htm).<br />

There is a vast and growing literature on<br />

this topic and we have not included all <strong>of</strong> the<br />

available information; the studies reviewed here<br />

are representative. Included in this section are<br />

studies focusing on diagnostic exposure, treatment<br />

for non-cancerous diseases, treatment for cancer,<br />

irradiation <strong>of</strong> adults and <strong>of</strong> children, in-utero<br />

exposure, and radiologists’ occupational exposure.<br />

As a practical matter an individuals’ decision to<br />

accept medical radiation exposure will always be<br />

a matter <strong>of</strong> balancing risks; hopefully this section<br />

can help inform that decision. Tables 3-1 through<br />

3-4 summarize the studies discussed below. Table<br />

3-1 includes diagnostic exposures to x-rays, tables<br />

3-2 and 3-3 include other exposures for diagnosis<br />

or treatment <strong>of</strong> benign disease, and Table 3-4 covers<br />

cancer survivors who received radiation therapy.<br />

3.2 Diagnostic exposures<br />

Diagnostic radiation, commonly used in modern<br />

medicine to detect the presence <strong>of</strong> health problems<br />

such as a bone break or a tumor, is the largest manmade<br />

source <strong>of</strong> radiation exposure to the general<br />

public. The doses that patients have received from<br />

this type <strong>of</strong> exposure have varied greatly over the<br />

Medical Exposures 21<br />

years and for the most part have been strategically<br />

reduced over time. Doses currently vary by procedure<br />

and by organ. A dental x-ray, for example, might<br />

result in a thyroid dose <strong>of</strong> 0.1 mGy while a CT chest<br />

scan 3 could result in doses <strong>of</strong> over 20 mGy to the<br />

breast, lung and esophagus. Figure 3-1 shows one set<br />

<strong>of</strong> “average” dose estimates for various procedures.<br />

A good source <strong>of</strong> organ-specific dose estimates is<br />

Berrington de Gonzalez and Darby 2004. Because<br />

these exposures are so common and are so carefully<br />

controlled (especially in recent years), they are a<br />

good source <strong>of</strong> data for epidemiologic research.<br />

Diagnostic x-rays. There is some evidence<br />

linking diagnostic x-rays with leukemia. Gibson et<br />

al. (1972) conducted a case-control study <strong>of</strong> leukemia<br />

in adults who had been exposed to diagnostic xrays<br />

in upstate New York, in Baltimore, and in<br />

Minneapolis-St.Paul. This study found significant<br />

risks <strong>of</strong> acute myeloid leukemia (AML) and chronic<br />

myeloid leukemia (CML) in males. The RRs for the<br />

lowest category <strong>of</strong> exposure, 11 or more x-rays, were<br />

1.61 (p

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