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Pediatric Informatics: Computer Applications in Child Health (Health ...

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8 Complexity <strong>in</strong> <strong>Health</strong>care Information Technology Systems 95<br />

hospitals to (perhaps <strong>in</strong> part prematurely) implement electronic “solutions” without<br />

fully understand<strong>in</strong>g how to specify, purchase, and implement, test and ma<strong>in</strong>ta<strong>in</strong><br />

<strong>Health</strong> IT systems that can manage the complex operational <strong>in</strong>terdependencies that<br />

have profound impact on safe patient care. 58–64<br />

The human culture of <strong>in</strong>patient <strong>Pediatric</strong> environments has evolved to a safer<br />

level: Today physicians, pharmacists, and allied health personnel work synergistically<br />

to deliver care. This coord<strong>in</strong>ated “symphony” delivers complex, time-sensitive care<br />

to many pediatric patients simultaneously and is often called “workflow.” In the<br />

<strong>in</strong>herently dynamic period of childhood, these providers work collaboratively to<br />

identify risk factors and prevent harm. In many cases, the <strong>in</strong>troduction of new<br />

technology <strong>in</strong>terrupts communication, redirects efforts, and places unanticipated<br />

stress on these delicate human systems, sometimes with untoward consequences.<br />

Change magnifies <strong>in</strong>efficiencies, demolishes exist<strong>in</strong>g work-arounds, and disrupts<br />

the delicate workflow balance that stabilizes a complex <strong>Pediatric</strong> ward.<br />

Scenario B addresses the <strong>in</strong>terrelationship of human factors and technology<br />

<strong>in</strong> a <strong>Pediatric</strong> ward, and describes the occult workflow problems that technol-<br />

ogy exposed. <strong>Child</strong>ren create dist<strong>in</strong>ctive challenges for medication order<strong>in</strong>g.<br />

<strong>Pediatric</strong> patients have threefold the risk of adults for suffer<strong>in</strong>g harm from a medication<br />

error. <strong>Pediatric</strong>ians must calculate medication doses based on weight, age,<br />

gestational age, and <strong>in</strong>dication, <strong>in</strong>creas<strong>in</strong>g the risk of cognitive and mathematical<br />

errors (e.g. the tenfold overdose error). 64 <strong>Pediatric</strong> pharmacists often work with<br />

adult formulations, and must manually compound suspensions and <strong>in</strong>travenous<br />

dilutions for use <strong>in</strong> pediatric patients. <strong>Child</strong>ren experience rapidly chang<strong>in</strong>g<br />

weights and sequentially chang<strong>in</strong>g laboratory normative values, which <strong>in</strong>creases<br />

risk for <strong>in</strong>correct dos<strong>in</strong>g. The immature renal and hepatic systems <strong>in</strong> children and<br />

neonates <strong>in</strong>consistently clear drugs, and limited physiologic reserve makes <strong>in</strong>fants<br />

more likely to be harmed by even modest medication errors. 64–66 <strong>Computer</strong> systems<br />

with <strong>in</strong>appropriate normal values and adult-based decision support modules<br />

<strong>in</strong>crease error risk. Efficient communication between providers helps mitigate this<br />

risk, but technology often constitutes a barrier to human <strong>in</strong>teraction.<br />

8.3.2 Scenario B: Situation Analysis<br />

Two published studies from major children’s hospitals with very different results on<br />

PICU mortality 8, 9 raise a key question: How can two <strong>Pediatric</strong> CPOE implementations,<br />

us<strong>in</strong>g the same commercial system, produce completely different patient<br />

mortality outcome results?<br />

8.3.2.1 Review: Comparison of the Case Details<br />

The Pittsburg <strong>Child</strong>ren’s Hospital 8 is a nationally recognized 235 bed tertiary<br />

pediatric care facility admitt<strong>in</strong>g about 12,000 pediatric patients per year; 25% of<br />

the admissions are directly to the hospital’s <strong>Pediatric</strong> ICU (PICU). Pittsburg<br />

64, 65

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