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Pediatric Informatics: Computer Applications in Child Health (Health ...

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100 W.H. Drummond et al.<br />

Table 8.2 (cont<strong>in</strong>ued)<br />

<strong>Child</strong>ren’s Hospital<br />

of Pittsburgh<br />

<strong>Child</strong>ren’s Hospital<br />

of Seattle<br />

Study results<br />

Methodology Retrospective design Retrospective design<br />

Comparison of “pre” and “post” There are no statistically There are multiple differences<br />

groups<br />

significant differences <strong>in</strong> the pre and post<br />

between the groups except groups. Most notably age<br />

for the number of patients (90.5 versus 83.25 mos)<br />

with CNS disease<br />

and the <strong>in</strong>cidence<br />

(288 pre, 89 post)<br />

of asthma, cancer,<br />

pneumonia, and sepsis<br />

Mortality rate Mortality statistics<br />

Mortality rate (all patients):<br />

( <strong>in</strong>ter-facility transfers pre 4.22–post 3.46%<br />

to PICU):<br />

Mortality rate (Inter-facility<br />

Pre 2.80% (39/1394) transfers to PICU)<br />

Post 6.57% (36/548) Pre 9.60–post 6.29%<br />

Factors affect<strong>in</strong>g mortality Patients younger, history<br />

of prematurity, direct<br />

admission to PICU<br />

Not evaluated<br />

Adjusted for confound<strong>in</strong>g factors Yes No<br />

Conclusion Unadjusted mortality rate is There is no significant<br />

significantly higher <strong>in</strong> the change <strong>in</strong> unadjusted<br />

“post” CPOE group. This mortality between the<br />

conclusion is likely the “pre” and “post” CPOE<br />

result of multiple socio- groups. However, this<br />

technical factors rather comparison of unadjusted<br />

than an isolated CPOE mortality rates may be<br />

system<br />

<strong>in</strong>valid due to significant<br />

differences between the<br />

pre and post groups, and<br />

the failure to adjust for<br />

confound<strong>in</strong>g factors<br />

attention to recogniz<strong>in</strong>g work flow changes needed for system adaptation to<br />

change generated by IT implementation.<br />

One of the fundamental differences between the two PICU CPOE <strong>in</strong>stallations<br />

was the substantial prelim<strong>in</strong>ary effort by Seattle <strong>in</strong> build<strong>in</strong>g pediatric ICU order<br />

sets. At Pittsburgh, a s<strong>in</strong>gle order took 1–2 m<strong>in</strong>. In Seattle, an entire “pre-built”<br />

set of admission orders could be entered <strong>in</strong> 5 m<strong>in</strong>. Even though clearly faster than<br />

Pittsburgh, 5 m<strong>in</strong> is still a fivefold <strong>in</strong>crease <strong>in</strong> provider effort compared to paper<br />

versions of the same order set. Accounts from both hospitals support the time sav<strong>in</strong>g<br />

value of pre-built order sets versus s<strong>in</strong>gle order entry. In the future, formal time,<br />

effort, and workflow analyses must be used to specify and build more efficient<br />

archival software, better user <strong>in</strong>terface utilities, team workflow support, and

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