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Pediatric Informatics: Computer Applications in Child Health (Health ...

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188 P.W. Dalrymple et al.<br />

For pediatricians, a common visual <strong>in</strong>formation need is identification of normal<br />

and abnormal sk<strong>in</strong> f<strong>in</strong>d<strong>in</strong>gs and their l<strong>in</strong>kage to disease states (“What is this<br />

rash?”). Practitioners may capture and store visual data on sk<strong>in</strong> samples us<strong>in</strong>g<br />

digital cameras, which can be forwarded electronically to remote experts for teleconsultation.<br />

Alternatively, onl<strong>in</strong>e image repositories may be helpful for additional<br />

discussions on unusual or <strong>in</strong>terest<strong>in</strong>g cases.<br />

Dermatlas (www.dermatlas.org) is a free, collaborative, open access repository<br />

(from Johns Hopk<strong>in</strong>s University School of Medic<strong>in</strong>e) of over 10,000 images<br />

contributed by more than 400 physicians worldwide. Cl<strong>in</strong>icians may enter cl<strong>in</strong>ical<br />

observations <strong>in</strong> text format, and then retrieve sk<strong>in</strong> images that correspond to<br />

their observations, thus help<strong>in</strong>g to confirm a diagnosis and po<strong>in</strong>t<strong>in</strong>g to additional<br />

resources for treatment and prognosis. Dermatlas has a differential diagnosis feature<br />

that l<strong>in</strong>ks visual f<strong>in</strong>d<strong>in</strong>gs to aid the diagnostic process. It also l<strong>in</strong>ks diagnoses to<br />

medical literature references (via PubMed) and other <strong>in</strong>formation resources.<br />

VisualDx (www.logicalimages.com/prodVDxProven.htm) is a subscriptionbased<br />

onl<strong>in</strong>e (or standalone) service (from Logical Images/Thomson <strong>Health</strong>care)<br />

that provides cl<strong>in</strong>ical images and reference text to guide cl<strong>in</strong>icians <strong>in</strong> mak<strong>in</strong>g<br />

diagnoses. Orig<strong>in</strong>ally developed for dermatology, this tool is be<strong>in</strong>g extended to<br />

other doma<strong>in</strong>s, <strong>in</strong>clud<strong>in</strong>g oral health. For sk<strong>in</strong> lesions, users may use a specially<br />

developed dermatology lexicon to enter lesion types, such as “lump or bump,”<br />

“scabs” or “raised lesions” to augment a search based on historical f<strong>in</strong>d<strong>in</strong>gs<br />

(exposures, previous diseases or travel).<br />

A common auditory <strong>in</strong>formation need is the dist<strong>in</strong>ction of functional and pathologic<br />

heart murmurs. Despite advanced technology for diagnos<strong>in</strong>g structural heart<br />

disease, auscultation is still the primary diagnostic exam<strong>in</strong>ation, and auditory<br />

identification of heart sounds and l<strong>in</strong>kage to structural lesions is an important<br />

pediatric skill. A library of heart sounds plays a similar role to the visual image<br />

repositories.<br />

CARD (www.murmurlab.com/card6) is an onl<strong>in</strong>e library of digitized heart<br />

sounds (from Johns Hopk<strong>in</strong>s University School of Medic<strong>in</strong>e) collected from<br />

pediatric patients who have undergone echocardiography. To date, the database<br />

conta<strong>in</strong>s over 5,000 <strong>in</strong>dividual record<strong>in</strong>gs from over 900 patients, represent<strong>in</strong>g a<br />

variety of normal and abnormal heart murmurs. The application allows adjustments<br />

<strong>in</strong> heart rates and frequencies and graphic render<strong>in</strong>g of sounds, provid<strong>in</strong>g<br />

an optimal learn<strong>in</strong>g and reference environment that can both educate and help<br />

determ<strong>in</strong>e whether to refer for additional work-up. It is available free of charge. 9<br />

13.3.2 Cl<strong>in</strong>ical Constellations<br />

A diagnosis is often made not on the basis of a s<strong>in</strong>gle f<strong>in</strong>d<strong>in</strong>g (except for pathognomonic<br />

associations), but on a co-occurrence of several f<strong>in</strong>d<strong>in</strong>gs <strong>in</strong> one patient.<br />

Constellations of f<strong>in</strong>d<strong>in</strong>gs (history, exam<strong>in</strong>ation, laboratory test results) associated

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