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Pediatric Informatics: Computer Applications in Child Health (Health ...

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12 Diagnostic Decision Support 173<br />

(as determ<strong>in</strong>ed by a plausibility score assigned by consensus of the study’s cl<strong>in</strong>ical<br />

co<strong>in</strong>vestigators). The effect was greater for medical students than residents and<br />

greater for residents than faculty, suggest<strong>in</strong>g a role for these systems <strong>in</strong> education.<br />

This study used two other systems, QMR and Iliad, both of which are no longer<br />

available, as the MDDSS.<br />

A validated composite score that holds promise for evaluat<strong>in</strong>g the usefulness<br />

of MDDSS 42 weighs the quality of differential diagnoses and management plans<br />

(<strong>in</strong>clud<strong>in</strong>g further test<strong>in</strong>g and treatment) on a user’s lists generated both before and<br />

after use of the MDDSS. The score rewards both relevance and comprehensiveness<br />

of differential diagnosis and management plans. The reliability and validity of this<br />

measure is based on data from 71 subjects on six simulated cases, however it is not<br />

clear how the MDDSS affected the subjects’ before and after results.<br />

12.6.2 Develop<strong>in</strong>g MDDSS: Scope, Vocabularies,<br />

Level of Detail<br />

MDDSS developers face several challenges <strong>in</strong> regard to medical vocabularies.<br />

The classification and nomenclature of diseases and f<strong>in</strong>d<strong>in</strong>gs are not always clear<br />

(<strong>in</strong> the context of decision-mak<strong>in</strong>g). Scope decisions, which diseases and f<strong>in</strong>d<strong>in</strong>gs<br />

to <strong>in</strong>clude (and exclude), can be controversial. Many MDDSS programs have<br />

specific names for entities such as “Pneumococcal Pneumonia” and “Mycoplasma<br />

pneumonia,” <strong>in</strong> their disease vocabularies and will list all pneumonias <strong>in</strong> their differential<br />

lists when pert<strong>in</strong>ent cl<strong>in</strong>ical f<strong>in</strong>d<strong>in</strong>gs are entered, even if the data available<br />

do not yet support a specific type of pneumonia. This approach confers advantages<br />

to both the developers and the users. Us<strong>in</strong>g specific disease names prevents such<br />

systems from need<strong>in</strong>g several hierarchical layers of disease vocabulary and the<br />

correspond<strong>in</strong>g knowledge relat<strong>in</strong>g more specific diseases to higher level disease<br />

processes. Also, the end-level diagnostic rem<strong>in</strong>ders displayed may be more useful<br />

<strong>in</strong> help<strong>in</strong>g the cl<strong>in</strong>ician build a differential diagnosis than would be a higher level<br />

term. “Lumpers” and “splitters” have a fertile field for discourse <strong>in</strong> the area of<br />

MDDSS. For example, <strong>in</strong> design<strong>in</strong>g a diagnostic rem<strong>in</strong>der system for general pediatrics,<br />

it may not be <strong>in</strong>itially clear if a diagnosis list should <strong>in</strong>clude “ADHD” alone or<br />

“ADHD <strong>in</strong>attentive type,” “ADHD hyperactive type” and “ADHD comb<strong>in</strong>ed type.”<br />

12.6.3 Us<strong>in</strong>g MDDSS: Education<br />

The Liaison Committee on Medical Education 43 lists two educational objectives<br />

that are relevant to teach<strong>in</strong>g diagnostic skills to medical students:<br />

ED-28: “Evaluation of problem solv<strong>in</strong>g, cl<strong>in</strong>ical reason<strong>in</strong>g, and communication<br />

skills”

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