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Pediatric Informatics: Computer Applications in Child Health (Health ...

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30 Error Report<strong>in</strong>g Systems 393<br />

30.5.3 Automatic Triggers<br />

A new method for identify<strong>in</strong>g errors is via “automatic triggers.” Triggers are<br />

computerized data that may be associated with an error or adverse event (such as an<br />

order for naloxone as a signal that an overdose of morph<strong>in</strong>e has occurred). Unlike<br />

most other error identification programs discussed, this type of error detection can<br />

occur <strong>in</strong> real-time (such as monitors with<strong>in</strong> CPOE systems). Thus, triggers have the<br />

potential to prevent worsen<strong>in</strong>g cl<strong>in</strong>ical situations while a patient is still hospitalized.<br />

A computerized surveillance system monitors for the occurrence of any trigger, as<br />

def<strong>in</strong>ed by the hospital or outpatient cl<strong>in</strong>ic. 33,34 Typically the triggers are from lab<br />

values (e.g. hypoglycemia, hyperkalemia) medication records (e.g. reversal agents<br />

like naloxone), microbiology laboratory triggers (e.g. new positive blood culture),<br />

radiology triggers (e.g. use of the word “fall” <strong>in</strong> the study’s justification) or adm<strong>in</strong>istrative<br />

data (e.g. readmission with<strong>in</strong> 24 h). 11<br />

With electronic cl<strong>in</strong>ical <strong>in</strong>formation, these types of triggers can be an excellent<br />

way to augment a robust adverse event detection program. Triggers can augment<br />

chart reviews (both paper and electronic), allow<strong>in</strong>g more effective and timeefficient<br />

pickup of errors than random or unscreened reviews. 35 Other advantages of<br />

triggers <strong>in</strong>clude a consistent methodology for identify<strong>in</strong>g adverse events over time.<br />

This consistency can produce more reliable results after <strong>in</strong>terventions are made to<br />

address the adverse events. Therefore the progress of an <strong>in</strong>stitution or cl<strong>in</strong>ic can be<br />

tracked and trended.<br />

The use of natural language process<strong>in</strong>g (NLP) to detect adverse events is evolv<strong>in</strong>g.<br />

The goal of NLP is to convert electronic narrative documents <strong>in</strong>to a coded<br />

form suitable for computer based analysis. The cod<strong>in</strong>g is based on pattern match<strong>in</strong>g.<br />

Therefore documents such as discharge summaries, cl<strong>in</strong>ical notes and daily<br />

progress notes can be searched for the occurrence of adverse events. 36<br />

Triggers have been used to develop a successful (nonelectronic) error identification<br />

program <strong>in</strong> neonatology that identifies errors at higher rates than exist<strong>in</strong>g<br />

methods. Researchers found a positive predictive value of each identified trigger<br />

to be 38%. S<strong>in</strong>ce neonatal <strong>in</strong>tensive care units are complex environments, the possibility<br />

for error is quite high (Chapter 4). In a published study, the trigger-based<br />

program captured several previously unidentified <strong>in</strong>stances of nosocomial <strong>in</strong>fection,<br />

catheter <strong>in</strong>filtrates, abnormal cranial imag<strong>in</strong>g and unplanned extubations.<br />

Although this program used manual chart review, the methodology can be adapted<br />

to an automated electronic form. 37 This approach has been extended to other areas<br />

of <strong>in</strong>patient pediatrics. 43<br />

Outpatient use of triggers is also possible. As the use of electronic medical<br />

records <strong>in</strong>creases <strong>in</strong> outpatient pediatric practices the ability to utilize triggers<br />

grows. Outpatient triggers have been utilized <strong>in</strong> an outpatient geriatric sett<strong>in</strong>g 38 and<br />

<strong>in</strong> other primary care cl<strong>in</strong>ics. 39<br />

Barriers to computer based screen<strong>in</strong>g to identify errors and adverse events are<br />

the low positive predictive value of their results. Therefore it is important to verify<br />

the accuracy of the system. Both <strong>in</strong>ternal and external validations are important. 11

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