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Part-I - Controller General of Patents Designs and Trademarks

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(12) PATENT APPLICATION PUBLICATION (21) Application No.3053/MUM/2010 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :03/11/2010 (43) Publication Date : 21/06/2013<br />

(54) Title <strong>of</strong> the invention : PHARMACEUTICAL COMPOSITIONS FOR COLLOIDAL DRUG DELIVERY<br />

(51) International classification<br />

(31) Priority Document No :NA<br />

(32) Priority Date :NA<br />

(33) Name <strong>of</strong> priority country :NA<br />

(86) International Application No<br />

:NA<br />

Filing Date<br />

:NA<br />

(87) International Publication No : NA<br />

(61) Patent <strong>of</strong> Addition to Application Number :NA<br />

Filing Date<br />

:NA<br />

(62) Divisional to Application Number<br />

:NA<br />

Filing Date<br />

:NA<br />

:A61K47/10;<br />

A61K9/107;<br />

(71)Name <strong>of</strong> Applicant :<br />

1)DR.(MRS) PADMA VENKITACHALAM<br />

DEVARAJAN<br />

Address <strong>of</strong> Applicant :DEPARTMENT OF<br />

PARMACEUTICALS SCIENCES AND TECHNOLOGY,<br />

INSTITUTE OF CHEMICAL TECHNOLOGY, MATUNGA,<br />

MUMBAI-19 INDIA Maharashtra India<br />

(72)Name <strong>of</strong> Inventor :<br />

1)DR. (MRS) PADMA VENKITACHALAM<br />

DEVARAJAN<br />

2)SONALI V. KAPSE<br />

3)ANIL B JINDAL<br />

(57) Abstract :<br />

The present invention relates to preparation <strong>of</strong> drug loaded heterogeneous nanosystems resulting from mixing <strong>of</strong> two monophasic<br />

phases, the non-aqueous phase comprising <strong>of</strong> active agent/s, polymers, lipids, surfactants, solubilizer/s <strong>and</strong> other excipients <strong>and</strong><br />

the aqueous phase comprising <strong>of</strong> buffers, isotonic solutions, sweetners, flavors <strong>and</strong> other excipients .The novel technique enables<br />

formation <strong>of</strong> stable colloidal particles with high drug loading <strong>and</strong> predictable size at the time <strong>of</strong> use. The invention represents a<br />

major step in circumventing the technological challenges in the design <strong>of</strong> colloidal particles which can remain suspended for at<br />

least 4h maintaining an effective average particle size <strong>of</strong>

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