Part-I - Controller General of Patents Designs and Trademarks

(12) PATENT APPLICATION PUBLICATION (21) Application No.1521/CHENP/2012 A
(19) INDIA
(22) Date of filing of Application :20/02/2012 (43) Publication Date : 21/06/2013
(54) Title of the invention : DETECTION OF DIFFERENT TARGET COMPONENTS BY CLUSTER FORMATION
(51) International classification :G01N33/543
(31) Priority Document No :09168150.2
(32) Priority Date :19/08/2009
(33) Name of priority country :EPO
(86) International Application No
Filing Date
(87) International Publication No : NA
(61) Patent of Addition to Application
:NA
Number
:NA
Filing Date
(62) Divisional to Application Number
Filing Date
:PCT/IB2010/053690
:16/08/2010
:NA
:NA
(71)Name of Applicant :
1)KONINKLIJKE PHILIPS ELECTRONICS N.V.
Address of Applicant :GROENEWOUDSEWEG 1
EINDHOVEN 5621 BA NETHERLANDS
(72)Name of Inventor :
1)RANZONI Andrea
2)OVSYANKO Mikhail Mikhaylovich
3)PRINS Menno Willem Jose
(57) Abstract :
The invention relates to a method, a test kit, and an apparatus (100) for detecting a plurality of different species of target
components (T1, T2) in a sample. This is achieved by using a plurality of classes of label particles (1, 2), wherein at least one of
the label particles (1, 2) in each class is a magnetic particle, and wherein label particles (1, 2) from each class can bind to each
other via the same class-specific species of target component. Clusters of label particles (1, 2) can then form in which binding to
specific target components (T1, T2) is accompanied by characteristic properties, for example magnetic susceptibilities of the
associated label particles (1, 2). The selective actuation of such clusters by a magnetic field (B) with at least one oscillating
component and a variable field amplitude together with the detection of such selectively actuated clusters will hence allow to
specifically detect the clusters. This provides information about the different target components (T1, T2) in the sample.
No. of Pages : 21 No. of Claims : 14
The Patent Office Journal 21/06/2013 13827