Part-I - Controller General of Patents Designs and Trademarks

(12) PATENT APPLICATION PUBLICATION (21) Application No.2095/CHE/2011 A
(19) INDIA
(22) Date of filing of Application :21/06/2011 (43) Publication Date : 21/06/2013
(54) Title of the invention : AN IMPROVED PROCESS FOR THE PREPARATION OF EFAVIRENZ
(51) International classification :A61K
(31) Priority Document No :NA
(32) Priority Date :NA
(33) Name of priority country :NA
(86) International Application No
:NA
Filing Date
:NA
(87) International Publication No : NA
(61) Patent of Addition to Application Number :NA
Filing Date
:NA
(62) Divisional to Application Number
:NA
Filing Date
:NA
(71)Name of Applicant :
1)MATRIX LABORATORIES LTD
Address of Applicant :PLOT NO 564/A/22, ROAD NO 92,
JUBILEE HILLS, HYDERABAD - 500 033 Andhra Pradesh
India
(72)Name of Inventor :
1)RAMA, SHANKAR
2)ABBINENI, JYOTHI BASU
3)KONUDULA, BABU RAO
4)KARUTURI, SRINIVASA RAO
5)GORANTLA, ADISESHAGIRI RAO
(57) Abstract :
The present invention relates to an improved process for the preparation of chiral alcohols compounds by asymmetric alkynylation
of ketones. The chiral alcohols are used in the preparation of HIV reverse transcriptase inhibitor such as Efavirenz.
No. of Pages : 14 No. of Claims : 11
The Patent Office Journal 21/06/2013 14017