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Part-I - Controller General of Patents Designs and Trademarks

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(12) PATENT APPLICATION PUBLICATION (21) Application No.1034/CHENP/2012 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :01/02/2012 (43) Publication Date : 21/06/2013<br />

(54) Title <strong>of</strong> the invention : METHOD AND APPARATUS OF DETERMINING EXHALED NITRIC OXIDE<br />

(51) International classification :A61B5/08<br />

(31) Priority Document No :09166814.5<br />

(32) Priority Date :30/07/2009<br />

(33) Name <strong>of</strong> priority country :EPO<br />

(86) International Application No<br />

Filing Date<br />

(87) International Publication No : NA<br />

(61) Patent <strong>of</strong> Addition to Application<br />

:NA<br />

Number<br />

:NA<br />

Filing Date<br />

(62) Divisional to Application Number<br />

Filing Date<br />

:PCT/IB2010/053361<br />

:23/07/2010<br />

:NA<br />

:NA<br />

(71)Name <strong>of</strong> Applicant :<br />

1)KONINKLIJKE PHILIPS ELECTRONICS N.V.<br />

Address <strong>of</strong> Applicant :GROENEWOUDSEWEG 1<br />

EINDHOVEN 5621 BA NETHERLANDS<br />

(72)Name <strong>of</strong> Inventor :<br />

1)VAN KESTEREN Hans Willem<br />

2)VINK Teunis Johannes<br />

3)WILLARD Nicolaas Petrus<br />

(57) Abstract :<br />

A method <strong>and</strong> apparatus <strong>of</strong> determining the level <strong>of</strong> exhaled nitric oxide (NO) is disclosed. The method involves measuring the<br />

level <strong>of</strong> exhaled NO (34) <strong>and</strong> the corresponding exhalation flow rate in one or more exhalations (30 32) <strong>of</strong> a tidal breathing<br />

manoeuvre performed by a subject. The data is used with a model describing the flow dependence <strong>of</strong> exhaled NO to derive a value<br />

for exhaled NO corresponding to a fixed flow rate especially to an exhaled NO level corresponding to a fixed flow rate <strong>of</strong> 50<br />

ml/s. During the manoeuvre a variation in flow restriction (31) may be applied so as to vary the overall flow rate <strong>of</strong> exhalation.<br />

The method <strong>of</strong>fers a simple <strong>and</strong> quick way to determine exhaled NO levels with good accuracy <strong>and</strong> is suitable for use with<br />

children.<br />

No. <strong>of</strong> Pages : 33 No. <strong>of</strong> Claims : 13<br />

The Patent Office Journal 21/06/2013 13633

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