Part-I - Controller General of Patents Designs and Trademarks

(12) PATENT APPLICATION PUBLICATION (21) Application No.1441/CHENP/2012 A
(19) INDIA
(22) Date of filing of Application :15/02/2012 (43) Publication Date : 21/06/2013
(54) Title of the invention : SYNTHESIS OF C-3 COUPLED BIFLAVONOIDS AND C-3 COUPLED BIFLAVONOID
ANALOGUES•
(51) International classification :C07D311/28
(31) Priority Document No :2009/05765
(32) Priority Date :19/08/2009
(33) Name of pr ority country :South Africa
(86) International Application No
Filing Date
(87) International Publication No : NA
(61) Patent of Addition to Application
:NA
Number
:NA
Filing Date
(62) Divisional to Application Number
Filing Date
:PCT/I 2010/053755
:19/08/2010
:NA
:NA
(71)Name of Applicant :
1)UNIVERSITY OF THE FREE STATE
Address of Applicant :Department of Chemistry Nelson
Mandela Drive 9301 Bloemfontein South Africa
(72)Name of Inventor :
1)VAN DER WESTHUIZEN Jan Hendrik
2)BONNET Susanna Lucia
3)ACHILONU Mathew
4)SISA Miroslav
(57) Abstract :
The invention relates to methods for the preparation of an optically inactive and optically active compounds which are selected
from the group consisting of C-3 coupled biflavonoids and C-3 coupled biflavonoid analogues from a starting material or
intermediate which are respectively selected from the group consisting of optically inactive or optically active flavan-3-ols and
optically active flavan-3-ones the method comprising the steps of (a) providing an optically inactive or active compound having a
fIavan-3-ol structure or a compound which is a flavan-3-one (b) if a compound having a flavan-3-ol structure with a hydroxy
group on the C-3 carbon is selected as starting material converting the hydroxy group on the C-3 carbon of the compound having
the flavan-3-ol structure to an oxo group to form a flavan-.....
No. of Pages : 28 No. of Claims : 15
The Patent Office Journal 21/06/2013 13792