Bulletin 2011/10 - European Patent Office
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(C07D) I.1(2)<br />

(51) C07D 333/36 (11) 2 292 611 A1<br />

A61K 31/381 A61K 31/4436<br />

A61K 31/4439 A61K 31/444<br />

A61K 31/496 A61K 31/5377<br />

A61P 1/00 A61P 1/04<br />

A61P 1/16 A61P 3/<strong>10</strong><br />

A61P 7/00 A61P 7/06<br />

A61P 9/00 A61P 9/<strong>10</strong><br />

A61P 11/02 A61P 11/06<br />

A61P 13/12 A61P 17/00<br />

A61P 17/06 A61P 19/02<br />

(25) Ja (26) En<br />

(21) 09750683.6 (22) 25.05.2009<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK TR<br />

AL BA RS<br />

(86) JP 2009/059494 25.05.2009<br />

(87) WO 2009/142321 2009/48 26.11.2009<br />

(30) 23.05.2008 JP 2008134902<br />

(54) • NEUES THIOPHENDIAMINDERIVAT MIT<br />

HARNSTOFFSTRUKTUR<br />

• NOVEL THIOPHENEDIAMINE DERIVATIVE<br />

HAVING UREA STRUCTURE<br />

• NOUVEAU DÉRIVÉ DE THIOPHÈNEDIA-<br />

MINE AYANT UNE STRUCTURE D URÉE<br />

(71) Santen Pharmaceutical Co., Ltd, 9-19, Shimoshinjo<br />

3-chome Higashiyodogawa-ku,<br />

Osaka-shi Osaka 533-8651, JP<br />

(72) MOGI, Hiroyuki, Ikoma-shi Nara 630-0<strong>10</strong>1,<br />

JP<br />

TAJIMA, Hisashi, Ikoma-shi Nara 630-0<strong>10</strong>1,<br />

JP<br />

MISHINA, Noriko, Ikoma-shi Nara 630-0<strong>10</strong>1,<br />

JP<br />

YAMAZAKI, Yusuke, Ikoma-shi Nara 630-<br />

0<strong>10</strong>1, JP<br />

YONEDA, Shinji, Ikoma-shi Nara 630-0<strong>10</strong>1,<br />

JP<br />

WATANABE, Katsuhiko, Ikoma-shi Nara 630-<br />

0<strong>10</strong>1, JP<br />

FUJIKAWA, Junko, Ikoma-shi Nara 630-<br />

0<strong>10</strong>1, JP<br />

YAMAMOTO, Minoru, Ikoma-shi Nara 630-<br />

0<strong>10</strong>1, JP<br />

(74) Müller-Boré & Partner <strong>Patent</strong>anwälte, Grafinger<br />

Straße 2, 81671 München, DE<br />

C07D 333/36 → (51) C07C 223/06<br />

C07D 333/66 → (51) C07C 223/06<br />

C07D 401/06 → (51) A61K 31/415<br />

C07D 401/<strong>10</strong> → (51) C07D 209/90<br />

(51) C07D 401/12 (11) 2 292 612 A2<br />

A61K 31/4439 A61P 1/00<br />

(25) En (26) En<br />

(21) <strong>10</strong>183275.6 (22) 30.12.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

AL BA MK RS<br />

(30) 31.12.2007 US 18021 P<br />

(54) • Kristalline und gelöste Formen von (R)-2-<br />

[[[3-methyl-4-(2, 2, 2-trifluorethoxy)-2pyridinyl-]methyl-]sulfinyl-]-1H-Benzoimidazol<br />

• Crystalline solvated forms of (R)-2-[[[3methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole<br />

• Formes dissoutes cristallines de (R) -2-<br />

[[[3-méthyl-4- (2, 2, 2-trifluoroéthoxy) -2pyridinyl]méthyl]sulfinyl]-1H-benzimidazole<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

(71) Takeda Pharmaceutical Company Limited, 1-<br />

1, Doshomachi 4-chome Chuo-ku, Osaka<br />

541-0045, JP<br />

(72) Urkami, Koji, Osaka 532-8686, JP<br />

Lorimer, Keith, Indiana, IN 47906, US<br />

Meyer, Keith, Indiana, IN 47906, US<br />

Andres, Mark, Christopher, Indiana, IN<br />

47906-1927, US<br />

(74) Oldroyd, Richard Duncan, Elkington and Fife<br />

LLP Prospect House 8 Pembroke Road,<br />

Sevenoaks, Kent TN13 1XR, GB<br />

(62) 08870<strong>10</strong>8.1 / 2 227 462<br />

C07D 401/14 → (51) C07D 209/60<br />

C07D 401/14 → (51) C07D 403/12<br />

C07D 403/04 → (51) C07D 209/60<br />

(51) C07D 403/06 (11) 2 292 613 A1<br />

A61K 31/404 A61P 35/00<br />

A61P 25/00 A61P 29/00<br />

A61P 37/00 A61P 9/00<br />

(25) Zh (26) En<br />

(21) 09749471.0 (22) 25.05.2009<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK TR<br />

AL BA RS<br />

(86) CN 2009/071967 25.05.2009<br />

(87) WO 2009/140928 2009/48 26.11.2009<br />

(30) 23.05.2008 CN 2008<strong>10</strong>098055<br />

(54) • DIHYDROINDOLINONDERIVATE<br />

• DIHYDROINDOLINONE DERIVATIVES<br />

• DÉRIVÉS DE DIHYDROINDOLINONE<br />

(71) Shanghai Institute of Pharmaceutical Industry,<br />

No. 1320 West Beijing Road, Shanghai<br />

200040, CN<br />

Jiangsu Chia Tai Tianqing Pharmaceutical<br />

Co., Ltd., No. 8 Julong North Road, Xinpu<br />

Lianyugang, Jiangsu 222006, CN<br />

(72) YUAN, Zhedong, Shanghai 200040, CN<br />

ZHANG, Xiaomin, Shanghai 200040, CN<br />

WANG, Hubo, Shanghai 200040, CN<br />

ZHU, Xueyan, Shanghai 200040, CN<br />

XU, Hongjiang, Jiangsu 2<strong>10</strong>038, CN<br />

FU, Hui, Jiangsu 2<strong>10</strong>038, CN<br />

SONG, Wei, Jiangsu 2<strong>10</strong>038, CN<br />

(74) Brand, Thomas Louis, W.P. Thompson & Co.<br />

55 Drury Lane, London WC2B 5SQ, GB<br />

C07D 403/06 → (51) A61K 31/415<br />

C07D 403/<strong>10</strong> → (51) C07D 209/60<br />

C07D 403/<strong>10</strong> → (51) C07D 209/90<br />

(51) C07D 403/12 (11) 2 292 614 A1<br />

C07D 401/14 C07D 403/14<br />

A61K 31/506<br />

(25) En (26) En<br />

(21) <strong>10</strong>183009.9 (22) 19.06.2003<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IT LI LU MC NL PT RO SE SI SK<br />

TR<br />

AL LT LV MK<br />

(30) 20.06.2002 US 390658 P<br />

18.09.2002 US 411609 P<br />

(54) • Substituierte Pyrimidines als Aurora Kinase<br />

Inhibitoren<br />

• Substituted pyrimidines as aurora kinase<br />

inhibitors<br />

• Pyrimidines substituées en tant qu'inhibiteurs<br />

d'aurora kinase<br />

(71) Vertex Pharmaceuticals Incorporated, 130<br />

Waverly Street, Cambridge, MA 02139, US<br />

224<br />

Anmeldungen<br />

Applications<br />

Demandes (<strong>10</strong>/<strong>2011</strong>) 09.03.<strong>2011</strong><br />

(72) Charrier, Jean-Damien, Wantage, Oxfordshire<br />

OX12 7LL, GB<br />

Kay, David, Purton, Wiltshire SN5 9DR, GB<br />

Mazzei, Francesca, Abingdon, Oxfordshire<br />

OX14 5TL, GB<br />

Miller, Andrew, Upton, Oxfordshire OX11<br />

9JL, GB<br />

(74) Coles, Andrea Birgit, et al, Kilburn & Strode<br />

LLP 20 Red Lion Street, London WC1R 4PJ,<br />

GB<br />

(62) 03739195.0 / 1 517 905<br />

(51) C07D 403/12 (11) 2 292 615 A1<br />

C07D 471/04 C07D 401/14<br />

C07D 491/04 A61K 31/517<br />

A61P 35/00<br />

(25) En (26) En<br />

(21) <strong>10</strong>185282.0 (22) 28.01.2003<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IT LI LU MC NL PT SE SI SK TR<br />

AL LT LV MK RO<br />

(30) 01.02.2002 EP 02290242<br />

(54) • Chinazoline Verbindungen<br />

• Quinazoline compounds<br />

• Dérivés de quinazoline<br />

(71) AstraZeneca AB, 151 85 Södertälje, SE<br />

(72) Hennequin, Laurent, Francois, Andre, 51689<br />

Reims, FR<br />

(62) 03700951.1 / 1 474 420<br />

C07D 403/14 → (51) C07D 403/12<br />

C07D 405/06 → (51) A61K 31/415<br />

C07D 405/12 → (51) A61K 31/415<br />

C07D 405/14 → (51) A61K 31/415<br />

C07D 405/14 → (51) C07D 313/00<br />

C07D 407/06 → (51) C07D 313/00<br />

C07D 407/12 → (51) A61K 31/7048<br />

C07D 409/06 → (51) A61K 31/415<br />

C07D 409/14 → (51) A61K 31/415<br />

C07D 413/<strong>10</strong> → (51) C07D 209/60<br />

(51) C07D 413/14 (11) 2 292 616 A1<br />

A61K 31/5377 A61P 7/02<br />

(25) De (26) De<br />

(21) <strong>10</strong>177691.2 (22) 22.09.2006<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC NL PL PT RO<br />

SE SI SK TR<br />

AL BA HR MK RS<br />

(30) 04.<strong>10</strong>.2005 DE <strong>10</strong>2005047564<br />

(54) • Neue polymorphe Form und die amorphe<br />

Form von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid<br />

• Novel polymorphic form and the amorphous<br />

form of 5-chloro-N-({(5S)-2-oxo-3-<br />

[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide<br />

• Nouvelle forme polymorphe et forme<br />

amorphe de 5-chlore-N-({(5S)-2-oxo-3-[4-<br />

(3-oxo-4-morpholinyl)-phényle]-1,3-oxazolidine-5-yl}-méthyle)-2-thiophencarboxamide<br />

(71) Bayer Schering Pharma Aktiengesellschaft,<br />

Müllerstrasse 178, 13353 Berlin, DE<br />

(72) Grunenberg, Alfons, 41539, Dormagen, DE<br />

Lenz, Jana, 42117, Wuppertal, DE<br />

Braun, Gerhard, 50733, Köln, DE

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