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The genus Cinnamomum

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320 B. Krishnamoorthy and J. Rema<br />

<strong>The</strong> aqueous extract of powdered bark exhibits appreciable activity against fluconazoleresistant<br />

and susceptible Candida, which causes mucosal candidosis. Chloroform extracts<br />

of cinnamon exhibited inhibitory activity on the growth and aflatoxin production of<br />

Aspergillus parasiticus (Sharma et al., 1984). Ueda et al. (1982) evaluated the antifungal and<br />

antibacterial properties of alcohol extracts of spices against several moulds and bacteria.<br />

<strong>The</strong> Minimum Inhibitory Concentration (MIC) of cinnamon on pathogenic bacteria is<br />

given in Tables 13.12, 13.13 and 13.14.<br />

Cinnamon bark oil is a powerful fungicide, germicide, insecticide and also inhibits<br />

aflatoxin production. Cinnamaldehyde, the major constituent of cinnamon and cassia<br />

barks, possesses antibacterial and antifungal activities. At 0.33 mm concentration it<br />

causes complete inhibition of Candida albicans, A. fumigatus, A. niger, Pencillium<br />

frequentans, P. decumbens and Cladosporium bantiannum.<br />

Cinnamon leaf oil is antimicrobial and is sensitive to yeast and filamentous fungi,<br />

including dermatophytes and moulds (Mangiarotti et al., 1990). Maruzzella and<br />

Lichtenstein (1958) tested a variety of volatile oils and found that volatile oils of<br />

Table 13.12 Minimum Inhibitory Concentration (%) of cinnamon in comparison with other major spices<br />

Spice pH B.s. S.a. E.c. S.t. S.m. P.a. P.v. P.m.<br />

Cinnamon 7.0 4.0 2.0 4.0 4.0 4.0 4.0 2.0 4.0<br />

5.0 0.5 2.0 2.0 4.0 4.0 4.0 1.0 2.0<br />

Cardamom 7.0 2.0 2.0 4.0 4.0 4.0 4.0 4.0 4.0<br />

5.0 0.1 0.5 4.0 4.0 4.0 4.0 2.0 4.0<br />

Celery 7.0 4.0 1.0 4.0 4.0 4.0 4.0 4.0 4.0<br />

5.0 0.5 1.0 4.0 4.0 4.0 4.0 2.0 4.0<br />

Cloves 7.0 1.0 1.0 1.0 1.0 1.0 2.0 1.0 1.0<br />

5.0 0.5 2.0 1.0 1.0 1.0 1.0 0.5 0.5<br />

Mace 7.0 0.2 0.05 4.0 4.0 4.0 4.0 4.0 4.0<br />

5.0 0.1 0.5 4.0 4.0 4.0 4.0 4.0 4.0<br />

Source: Hirasa and Takemasa, 1998.<br />

Notes<br />

B.s. – Bacillus subtilis; S.a. – Staphylococcus aureus; E.c. – Escherichia coli; S.t. – Salmonella typhimurium; S.m. – Salmonella<br />

marcescens; P.a. – Pseudomonas aerugenosa; P.v. – Proteus vulgaris; P.m. – Proteus morgani.<br />

Table 13.13 Minimum Inhibitory Concentration (%) of cinnamon for fungi in comparison with other<br />

major spices<br />

Spice S.c. C.p. C.k. P.sp. A.o.<br />

Cinnamon 1.0 1.0 1.0 1.0 1.0<br />

Cardamom 4.0 4.0 4.0 4.0 4.0<br />

Caraway 4.0 4.0 4.0 4.0 4.0<br />

Celery 4.0 4.0 4.0 10.0 10.0<br />

Cloves 0.5 0.5 0.5 0.5 0.2<br />

Mace 4.0 4.0 4.0 4.0 4.0<br />

Source: Hirasa and Takemasa, 1998.<br />

Notes<br />

S.c. – Saccharomyces cerevisiae; C.p. – Candida parakrusei; C.k. – Candida krusei; P.sp. – Pencillium sp.;<br />

A.o. – Aspergillus oryzea.

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