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preface to fifteenth edition

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8.58 SECTION 8<br />

TABLE 8.8<br />

pK a Values of Organic Materials in Water at 25C (Continued)<br />

Substance pK 1 pK 2 pK 3 pK 4<br />

4-Methylamino-3-methylpyridine 9.83(1)<br />

(20C)<br />

(3-Methylamino)phenylphosphonic 1.1(1) 4.72(1) 7.30(1)<br />

acid<br />

(4-Methylamino)phenylphosphonic — — 7.85(1)<br />

acid<br />

3-(Methylamino)pyridine (30C) 8.70(1)<br />

4-(Methylamino)pyridine (20C) 9.65(1)<br />

4-(Methylamino)-2,3,5,6-tetramethylpyridine<br />

10.06(1)<br />

(20C)<br />

N-Methylaniline<br />

4.85(1)<br />

Methylarsonic acid (18C) 3.41 8.18<br />

1-Methylbarbituric acid<br />

4.35(1)<br />

5-Methylbarbituric acid<br />

3.386(1)<br />

2-(N-Methylbenzamido)pyridine 1.44(1)<br />

3-(N-Methylbenzamido)pyridine 3.66(1)<br />

4-(N-Methylbenzamido)pyridine 4.68(1)<br />

2-Methylbenzimidazole ( 0.16) 6.29(1)<br />

2-Methylbenzoic acid (o-<strong>to</strong>luic 3.90<br />

acid)<br />

3-Methylbenzoic acid 4.269<br />

4-Methylbenzoic acid 4.362<br />

N-Methyl-1-benzoylecgonine 8.65<br />

Methylbiguanidine 3.00(2) 11.44(1)<br />

2-Methyl-2-butanethiol 11.35<br />

2-Methylbutanoic acid 4.761<br />

3-Methylbutanoic acid (20C) 4.767<br />

(E)-2-Methyl-2-butendioic acid 3.09 4.75<br />

(mesaconic acid)<br />

3-Methyl-2-butenoic acid 5.12<br />

(E)-2-Methyl-2-butenoic acid<br />

4.96<br />

(tiglic acid)<br />

(Z)-2-Methyl-2-butenoic acid (angelic<br />

4.30<br />

acid)<br />

4-Methylcarboxylphenol 8.47<br />

(E)-2-Methylcinnamic acid 4.500<br />

(E)-3-Methylcinnamic acid 4.442<br />

(E)-4-Methylcinnamic acid 4.564<br />

1-Methylcyclohexane-1-carboxylic 5.13<br />

acid<br />

cis-2-Methylcyclohexane-1-carboxylic<br />

5.03<br />

acid<br />

trans-2-Methylcyclohexane-1-carboxylic<br />

5.73<br />

acid<br />

cis-3-Methylcyclohexane-1-carboxylic<br />

4.88<br />

acid<br />

trans-3-Methylcyclohexane-1-carboxylic<br />

5.02<br />

acid<br />

cis-4-Methylcyclohexane-1-carboxylic<br />

5.04<br />

acid<br />

trans-4-Methylcyclohexane-1-carboxylic<br />

4.89<br />

acid<br />

2-Methylcyclohexyl-1,1-diacetic<br />

acid<br />

3.53 6.89

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