The Impact of Pesticides - Academy Publish

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About authorsSection 1HUMAN EXPOSURE TO PESTICIDESCarbamates: Human Exposure and Health Effects, p.21-p.38Simone Morais, Elsa Dias, Maria de Lourdes PereiraSimone Morais is a Professor at the Department of Chemical Engineering at thePolytechnic Engineering Institute of Porto (Portugal) and permanent researcherat REQUIMTE, the largest network in Chemistry and Chemical Engineeringestablished in Portugal. Her research interests include Analytical Chemistry andElectrochemistry, Food Safety and Air Pollution. S. Morais co-authored severalpapers in international refereed journals.Simone Morais, Adjunct ProfessorREQUIMTE, Instituto Superior de Engenharia do Porto, Rua Dr. AntónioBernardino de Almeida 431, 4200-072 Porto, Portugal.sbm@isep.ipp.ptElsa Dias is Principal Technician of Clinical Analyses and Public Health atLaboratory of Clinical Pathology, Hospital D. Pedro (Aveiro, Portugal). In addition,she is a researcher at Aveiro University, where carbamate toxicological studies onlaboratory animals have been undertaken.Elsa DiasDepartment of Biology, CICECO,University of Aveiro, Aveiro, Portugalelsadias@ua.ptMaria de Lourdes Pereira is a professor of Cell Biology, Cytology and Histology,and Human Biology, and was Director of the Molecular and Cell Biology Mastercourse. As a member of Research Centre on Ceramic and Composite Materials(CICECO) from Aveiro University, current research is directed to the adverseeffects of some pollutants (heavy metals, pesticides) on different target organs ofmice, combining histological, histochemistry, and ultrastructural approaches. M. L.Pereira co-authored several publications in the area of environment toxicology, andandrology, collaborating with some journals as referee.Maria de Lourdes PereiraAssociate Professor with AggregationDepartment of Biology, CICECO,University of Aveiro, Aveiro, Portugalmlourdespereira@ua.ptNeurotoxic Disorders and Medical Management of Patients Poisoned withOrganophosphorus and Carbamate Pesticides , p.39-p.62Professor Milan Jokanović is employed at Faculty of Medicine, University of Nish,Nish, Serbia. He is a member of Academy of Sciences and Arts of the RepublicSrpska in Banja Luka. He is also a member of Editorial Board of “Toxicology”AcademyPublish.org - The Impact of Pesticides8
About authorspublished by Elsevier.Professor Jokanović published more than 100 papers and book chapters ontoxicology of organophosphorus compounds, antidotes and medical treatment ofpoisoning. He is also an expert for nonclinical and clinical drug development andregulatory affairs. More details about his work and expertise can be found at www.experta.co.rs.The Role of Human Paraoxonase-1 (PON1) as a Modulator ofOrganophosphorousPesticide Adverse Effects , p.63-p.77Betzabet Quintanilla-Vega, Norma Pérez-Herrera and Aurora Elizabeth Rojas-GarcíaBetzabet Quintanilla-Vega, PhDAssociate ProfessorDepartment of ToxicologyCINVESTAV-IPNMexico City, MexicoAurora Elizabeth Rojas-García, PhDAssociate ProfessorSecretariat of Postgraduate and Research Autonomous University of NayaritNayarit, MexicoNorma Pérez-Herrera, PhDAssistant ProfessorLaboratory of Chronic and Degenerative Diseases Inter-Agency Unit of Clinical andEpidemiological Research Faculty of Medicine Autonomous University of YucatanYucatan, MexicoOccupational exposure to pesticides mixtures: oxidative balance, enzymaticbiomarkers and genetic damage in an Argentinian population study, p.78-p.104Marta Ana Carballo, Elisa Carlotta Kleinsorge, María Fernanda SimonielloProf. Phd. Marta Ana Carballomacarballo2003@yahoo.com.arUsing a Toxicokinetic Modeling Approach to Determine Biological ReferenceValues (Bvrs) and to Assess Human Exposure to Pesticides, p.105-p.142Aurélie Berthet, Michèle Bouchard, Mathieu Valcke, Roberto Heredia-OrtizAurélie Berthet has a Bachelor’s degree in biology and a Ph.D. in toxicology andpublic health. As part of her PhD project in human toxicology, she determinedAcademyPublish.org - The Impact of Pesticides9
Page 1 and 2: The Impactof PesticidesEdited by:Pr
Page 3 and 4: Other access free resources from Ac
Page 5 and 6: The Impact of PesticidesPrepared an
Page 7: Table of Contentsp.203-p.224 Behavi
Page 11 and 12: About authorsof medical researchers
Page 13: About authorsdifferent spatial scal
Page 16 and 17: About authorsEducation:Bachelor’s
Page 18 and 19: About authorsSensors - A Nanotechno
Page 20 and 21: Section 1HUMAN EXPOSURE TO PESTICID
Page 22 and 23: ecently explored on preliminary stu
Page 24: individuals within 1 day (Jokanovic
Page 27 and 28: occupational environmental health r
Page 30 and 31: must be considered, since effective
Page 34 and 35: Jensen BH, Petersen A, and Christen
Page 36 and 37: Ragas AMJ, and Huijbregts MAJ (1998
Page 38 and 39: Weichenthal S, Moase C, and Chan P
Page 40 and 41: human poisoning, general acute symp
Page 42 and 43: Management of the cholinergic syndr
Page 44 and 45: 1982; Lotti, 1992; Jokanović et al
Page 46 and 47: exposed populations, revealed high
Page 48 and 49: DiazepamBenzodiazepines are CNS dep
Page 50 and 51: Among the many classes of oximes in
Page 52 and 53: inhibited by dichlorvos (a dimethox
Page 54 and 55: Dawson, 1995). It appears that the
Page 56 and 57: Eddleston M, Eyer P, Worek F, Moham
Page 58 and 59:
Jokanović M, Kosanović M (2010b).
Page 60 and 61:
Ray DE (1998). Chronic effects of l
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Worek F, Eyer P, Kiderlen D, Thierm
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developing countries is due to suic
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count and morphology, as well as se
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PON1 modulation of genetic damageFe
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elationship between OP exposure and
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Blatter-Garin MC, James RW, Dussoix
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Hung RJ, Hall J, Brennan P, Boffett
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Rojas-García AE., Solís-Heredia M
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Occupational Exposure to Pesticides
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considered as conditions typical of
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observed adverse health outcome. Su
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within cells can oxidize biomolecul
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of the study. A face-to-face questi
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PesticidesFungicideInsecticide-Nema
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Table 4. Mixtures of pesticides use
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In pesticide applicators, Table 7 s
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DISCUSSIONThe agricultural workers
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changes in the antioxidant enzyme C
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Bajpayee, M.; Pandey, A. K.; Parmar
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Environmental health criteria 155.
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Palus, J.; Rydzynski, K.; Dziubalto
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Singh, N.P.; McCoy, M.T.; Tice, R.R
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INTRODUCTIONPopulations may be occu
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exposure scenarios on the basis of
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not present adverse health effects
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greenhouse workers exposed to malat
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Paraoxon is then either metabolized
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cyclohexene-1,2-dicarboximide, CAS
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metabolite of phthalates, such that
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scenarios were simulated, assuming
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Table 2. Biological reference value
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References N a urinarybiomarkeStudi
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Figure 2. Representation of a BRV d
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Figure 4. Conceptual representation
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Figure 6 Conceptual representation
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REFERENCESACGIH, 2011. Documentatio
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Bradway, D.E., Shafik, T.M., 1977.
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EPA, 1999b. Registration Eligibilit
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Hines, C.J., Deddens, J.A., Jaycox,
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McCollister, S.B., Kociba, R.J., Hu
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Verberk, M.M., Brouwer, D.H., Brouw
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important IGFBP for binding IGF-1 i
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secretion of IGF-1 (Tannheimer et a
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FIGURESFig. 1. An “hormetic” ef
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Landi F, Capoluongo E, Russo A, Ond
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Smith WJ, Underwood LE, Clemmons DR
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Section 2PESTICIDES IN THEENVIRONME
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vicinity of subsoil waters and ther
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Hieracium pilosella, southernwood -
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formed clusters (Figure 3). Ultrast
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Fig. 5. Fragment of hepatocyte of t
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Szarek, J, Skibniewska, K, Wojtacka
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negative effects (ZALUCKI et al., 2
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Figure 2. Appropriated sampling pro
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Figure 4. Illustration of the conse
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(HAILE et al., 1998). Earlier resul
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Table 1. Distribution of the applic
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Means followed by the same letter i
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(involving pests and natural enemie
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efore the pest emergence and their
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Table 3 (continuation)…AcademyPub
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Table 5. Effect of different fungic
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Table 6. Magament used including do
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adopted by Brazilian soybean grower
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Pickle, C.S.; Caviness, C.E. Yield
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This chapter reports on Dutch surfa
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several different occasions at any
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The greatest number of pesticides a
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Accumulated ExceedanceIt is useful
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For the years 2003-2009 the calcula
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Bonzini S, Verro R, Otto S, Lazzaro
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atios of the pesticide amounts in t
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Table 1. (Cont.) Runoff ratios of p
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mefenacet and simetrin were observe
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Table 2. (Cont.)Pesticide concentra
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Table 2. (Cont.)Pesticide concentra
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Fig. 3. Typical weekly variation of
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(BAM) in water (Pukkila et al. 2009
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Table 5. Concentrations of pesticid
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Table 6. Maximum concentrations of
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Iwafune, T, Inao, K, Horio, T, Iwas
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Suzuki, M, Takemine, S, Yoshida, M,
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factor, etc. Levels of pesticides i
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factor of 10 above ambient sea wate
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weight sample. Minimum were shown f
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Figure 3. DDTs in mussel samples fo
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Figure 5. HCB in mussel samples for
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Figure 8. Methoxychlor in mussel sa
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ACKNOWLEDGEMENTAuthors thank UNEP/M
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Pesticide Risk Index of Del Azul Wa
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on that presented in Swanson et al.
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eference value for that substance.
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predict the aquatic toxicity of a s
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Calculation Model of Aggravating Fa
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To estimate the values of Human Hea
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water in comparison with the durati
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Cypermethrin (95 th percentile (P 9
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Table 8 shows the results of the De
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are many ranking systems of dangero
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REFERENCESAres J. (2004). “Estima
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Mackay D. and Paterson S. (1991).
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Long-term Monitoring of Pesticides
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Sampling sites of the survey in 200
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than those in Lake Biwa and Seta Ri
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Fig. 7 Detection of fungicides in R
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Fig. 11 Detection of herbicides in
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Monitoring of pesticides in Yanamun
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A measured volume (1000 mL) of the
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SimetrynePretilachlorConcentration
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Fig. 18 Maximum concentrations of t
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Ecological risk assessmentFig. 20 Y
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REFERENCESAgradi E, Baga R, Cillo F
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Time Trend Variation of Selected Pe
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Table 1. Physical and chemical prop
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marketed under variety of trade nam
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Figure 3. Long-term trends of globa
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laboratory animals fed or injected
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fed for a lifespan at 5-1,600 mg/kg
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Soil samplingSoil sampling was foll
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Figure 5. Map showing sampling area
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concentration (MAC) in surface soil
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Table 7. Concentrations of HCH isom
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Shanghai and Guanting Reservoir (Ch
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Contrary to the results of ΣDDT, t
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DDT metabolites, the ratio of (p,p
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2001). Therefore, the predominance
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Mean concentration (ng g -1 dw)3002
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CONCLUSIONSAn evaluation of selecte
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Hung, D.Q., Thiemann, W., (2002),
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Viet, P.H., Hoai, P.M., Minh, N.H.,
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found in tissues or fluids samples
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Study area and SamplingThis study w
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the liver, mainly to p,p'-DDE and p
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33,370 ha, whilst that of woody cro
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Increase in crops area (x1000)Ha)25
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Table 1. Blood concentrations of or
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Council Directive 90/533/EEC of 15
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Konstantinou, IK, Goutner, V, Alban
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Smith, AG (2004). “Toxicology of
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Pesticides are used in order to pro
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EXPERIMENTALMaterialsIsoproturon wa
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RESULTS AND DISCUSIONEquilibrium is
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As seen in Table 4, as the concentr
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Fig.4. Breakthrough curves of isopr
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Fig.6. Breakthrough curves of isopr
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Fig.8. Experimental and theoretical
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Section 3PESTICIDE ANALYSISAcademyP
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scandal’ are familiar to the gene
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ecoveries (>70%) for certain pH-dep
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Due the versatility of the QuEChERS
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of application, with some still sca
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The main supercritical solvent used
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extracting the pesticides from the
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would be appropriate for the routin
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chromatography with negative-ion el
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GPC was applied as a nondestructive
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Charlton A.J.A., Stuckey, V. (2009)
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Lehotay, S.J., Mastvoska, K. & Yun,
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Rodrigues, F. M., Mesquita, P. R. R
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Analytical methods to assess the im
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acetylcholine, a neurotransmitter t
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1.3 to 22.3% for all pesticides. Li
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Malathion, parathion, fenitrothion,
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Fuller, BH and Berger, GMB (1990).
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Table 1. Largest exporters of coffe
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Fig. 1: Structures of (a) Phosphate
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ELECTROCHEMICAL BIOSENSORBiosensors
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inorganic and organic species a lar
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surface area and be easily modified
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Acetylcholine + H 2 O AChE Choline
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Wang, 2010) and tetracyanoquinodime
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PDDA/AChE/PDDA/CNT/GCAChE-Au-PPy/GC
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ng/mL and good precision (RSD ) 5.3
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FUTURE PERSPECTIVESThe detection of
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Du, D; Wang, M; Cai, J; Qin, Y; Zha
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Martorell, D; Cespedes, F; Fabreaga
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The Pesticide Action Network (PAN).
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About EditorMilan JokanovićProfess
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THE IMPACT OF PESTICIDESPesticides
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