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Fiabilidad de los predictores clínicos y de la biopsia de arteria ...

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<strong>Fiabilidad</strong> <strong>de</strong> <strong>los</strong> <strong>predictores</strong> <strong>clínicos</strong> y <strong>de</strong> <strong>la</strong> <strong>biopsia</strong> <strong>de</strong> <strong>arteria</strong> temporal en el diagnóstico <strong>de</strong> <strong>la</strong> arteritis <strong>de</strong> célu<strong>la</strong>s gigantes<br />

Joan Brunsó Casel<strong>la</strong>s<br />

300<br />

250<br />

200<br />

150<br />

100<br />

50<br />

0<br />

Figura 58: Diagrama que muestra <strong>la</strong> distribución <strong>de</strong> <strong>los</strong> pacientes según el nivel <strong>de</strong> PCR:<br />

mayor o menor a 4 mg/L.<br />

P=0.000<br />

105<br />

166<br />

56<br />

15<br />

PCR ≤ 4 PCR > 4<br />

Un rango <strong>de</strong> PCR > 4 mg/ L concentra <strong>la</strong> mayor proporción <strong>de</strong> resultados positivos <strong>de</strong><br />

<strong>la</strong> BAT. Un valor <strong>de</strong> <strong>la</strong> PCR > 4 mg/L se asocia con un resultado positivo <strong>de</strong> <strong>la</strong> BAT<br />

(p=0.000) y presenta una especificidad muy alta: 91.17% (fig. 58).<br />

103<br />

[95% Confi<strong>de</strong>nce Interval]<br />

---------------------------------------------------------------------------<br />

Prevalence Pr(A) 21% 17% 25.5%<br />

---------------------------------------------------------------------------<br />

Sensitivity Pr(+|A) 34.78% 29.3% 39.2%<br />

Specificity Pr(-|N) 91.17% 85.6% 96.6%<br />

ROC area (Sens. + Spec.)/2 .629 .575 .694<br />

---------------------------------------------------------------------------<br />

Likelihood ratio (+) Pr(+|A)/Pr(+|N) 3.93 2.68 4.81<br />

Likelihood ratio (-) Pr(-|A)/Pr(-|N) .71 .574 .862<br />

Odds ratio LR(+)/LR(-) 5.53 3.82 7.98<br />

Positive predictive value Pr(A|+) 78.87 % 64.3% 84.2%<br />

Negative predictive value Pr(N|-) 38.74% 33.6% 44.9%<br />

--------------------------------------------------------------------<br />

BAT positiva<br />

BAT negativa

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