Industrial Biotransformations

Common name of enzyme
Name of strain
X.X.X.X = enzyme nomenclature number
1) Reaction conditions
[N]: molar concentration, mass concentration [molar mass] of component N
pH: pH of reaction solution
T: reaction temperature in °C
medium: type of reaction medium: in most cases aqueous, but can also be several phases
in combination with organic solvents
reaction type: suggestion of enzyme nomenclature for the type of enzymatic catalyzed reaction
catalyst: application of catalyst: solubilized / immobilized enzyme / whole cells
enzyme: systematic name (alternative names)
strain: name of strain
CAS (enzyme): [CAS-number of enzyme]
2) Remarks
1 2
EC X.X.X.X
1 = name of starting material
2 = name of product
name of company
Fig. X.X.X.X – 1
Only the enzyme catalyzed step, racemization and
regeneration reactions are shown.
O
The enzymatic step is indicated by a
bold arrow with an E over it.
E
+ H 2
● Since in the chemical drawing on top of the page only the enzymatic step is shown, prior or
subsequent steps, which might be part of the industrial process can be found here.
● Since it is often difficult to gain knowledge of the true industrial process conditions, those
published in the past for the same reaction system are given.
● Besides the already mentioned topics you will find additional information regarding the discussed
biotransformation, e.g. substrate spectrum, enzyme improvement, immobilization
methods, and all other important information which does not fit to another category.
● If an established synthesis is replaced by a biotransformation, the classical, chemical synthesis
can be found here as well.
OH
149