Industrial Biotransformations

Haloalkane dehalogenase
Alcaligenes sp. or Pseudomonas sp.
EC 3.8.1.5
● Suzuki, T., Kasai, N., Yamamoto, R., Minamiura, N. (1992) Isolation of a bacterium assimilating
(R)-3-chloro-1,2-propanediol and production of (S)-3-chloro-1,2-propanediol using microbial
resolution, J. Ferment. Bioeng. 73, 443–448
● Suzuki, T., Kasai, N., Yamamoto, R., Minamiura, N. (1993) Production of highly optically active
(R)-3-chloro-1,2-propanediol using a bacterium assimilating the (S)-isomer, Appl. Microbiol.
Biotechnol. 40, 273–278
● Suzuki, T., Kasai, N., Yamamoto, R., Minamiura, N. (1994) A novel enzymatic dehalogenation
of (R)-3-chloro-1,2-propanediol in Alicaligenes sp. DS-S-7G, Appl. Microbiol. Biotechnol. 42,
270–279
● Suzuki, T., Kasai, N., Minamiura, N. (1994) A novel generation of optically active 1,2-diols
from the racemates by using halohydrin dehydro-dehalogenase, Tetrahedron: Asymmetry 5,
239–246
● Suzuki, T., Kasai, N., Yamamoto, R., Minamiura, N. (1994) Microbial production of optically
active 1,2-diols using resting cells of Alcaligenes sp. DS-S-7G, J. Ferment. Bioeng. 78, 194–196
● Suzuki, T., Idogaki, H., Kasai, N. (1996) A novel generation of optically active ethyl-4-chloro-3hydroxybutyrate
as a C4 chiral building unit using microbial dechlorination, Tetrahedron:
Asymmetry 7, 3109–3112
● Suzuki, T., Idogaki, H., Kasai, N. (1996) Production of (S)-4-chloro-3-hydroxybutyronitrile
using microbial resolution, Bioinorg. Med. Chem. Lett. 6, 2581–2584
442