Industrial Biotransformations

Alcohol dehydrogenase
Rhodococcus erythropolis
6) Literature
EC 1.1.1.1
● Bracher, F., Litz, T. (1994) Building blocks for the preparation of enantiomerically pure drugs
containing a phenylalkylamine moiety, Arch. Pharm. 327, 591–593
● Johnston, B., Slessor, K. (1979) Facile synthesis of the enantiomers of sulcatol, Can. J. Chem.
57, 233–235
● Kragl, U., Kruse, W., Hummel, W., Wandrey, C. (1996) Enzyme engineering aspects of biocatalysis:
Cofactor regeneration as example, Biotechnol. Bioeng. 52, 309–319
● Kruse, W., Hummel, W., Kragl, U. (1996) Alcohol-dehydrogenase-catalyzed production of
chiral hydrophobic alcohols. A new approach leading to a nearly waste-free process, Recl. Trav.
Chim. Pays-Bas 115, 239–243
● Kruse, W., Kragl, U., Wandrey, C. (1996) Verfahren zur kontinuierlichen enzymkatalysierten
Gewinnung hydrophober Produkte, Forschungszentrum Jülich GmbH, DE 4436149 A1
● Kruse, W., Kragl, U., Wandrey, C. (1998) Process for the continuous enzymatic extraction of
hydrophobic products and device suitable therefor, Forschungszentrum Jülich GmbH, Germany,
US 5,795,750
● Liang, S.; Paquette, L.A. (1990) Biocatalytic-based synthesis of optically pure (C-6)-functionalized
1-(tert-butyldimethyl-silyloxy)-2-methyl-(E)-2-heptenes; Tetrahedron Asym. 1, 445–
452
● Mori, K. (1975) Synthesis of optically active forms of sulcatol – The aggregation pheromone in
the scolytid beetle, Gnathotrichus sulcatus, Tetrahedron 31, 3011–3012
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