Industrial Biotransformations

Lipase
Burkholderia plantarii
3) Flow scheme
Fig. 3.1.1.3 – 4
NH 2
4) Process parameters
conversion: 50 %
yield: > 90 %
ee: > 99 % (S); 93 % (R)
reactor type: plug-flow reactor or batch
capacity: > 100 t · a –1
residence time: 5–7 h
down stream processing: distillation or extraction
production site: BASF AG, Germany
company: BASF AG, Germany
start-up date: 1993
5) Product application
+
O
● Products are intermediates for pharmaceuticals and pesticides.
● They can also be used as chiral synthons in asymmetric synthesis.
O
O
NH 2
NH
O
EC 3.1.1.3
O
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