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Document 58. Baker NJ, Gandhi SS. Effect of Ca++ on the stability of influenza virus neuraminidase. Arch Virol 1976; 52:7–18. 59. Burmeister WP, Cusack S, Ruigrok RWH. Calcium is needed for the thermostability of influenza B virus neuraminidase. J Gen Virol 1994; 75:381–388.87. 60. Wagh PV, Bahl OP. Sugar residues on proteins. Crit Rev Biochem 1981; 307–377. 61. Hitte AL, Nayak DP. Complete nucleotide sequences of the neuraminidase gene of human influenza virus A/WSN/33. J Virol 1982; 41:730–734. 62. Li S, Schulman J, Itamura S, Palase P. Glycosylation of neuraminidase determines the neurovirulence of influenza A/WSN/33 virus. J Virol 1993; 67:6667–6673. 63. Ward CW, Murry JM, Roxburgh CM, Jackson DC. Chemical and antigenic characterisation of the carbohydrate side chains of an Asian (N2) influenza virus neuraminidase. Virology 1983; 126:370–375. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_483.html (2 of 2) [4/9/2004 12:28:58 AM]
Document 64. Ward CW, Elleman TC, Azad AA. Amino acid sequence of the pronase-released heads of neuraminidase subtype N2 from the Asian strain A/Tokyo/3/67 of influenza virus. Biochem J 1982; 207:91–95. Page 484 65. Colman PM, Varghese JN, Laver WG. Structure of the catalytic and antigenic sites in influenza virus neuraminidase. Nature 1983; 303:41–44. 66. Varghese JN, McKimm-Breschkin JL, Caldwell JB, Kortt AA, Colman PM. The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor. Proteins 1992; 14:327–332. 67. Colman PM, Laver WG, Varghese JN, Baker AT, Tullock PA, Air GM, Webster RG. Threedimensional structure of a complex of antibody with influenza virus neuraminidase. Nature 1987; 326:358–363. 68. Colman PM, Tulip WR, Varghese JN, Tulloch PA, Baker AT, Laver WG, Air GM. 3-D structures of influenza virus neuraminidase-antibody complexes. Proc Roy Soc Lond 1989; B,323:511–518. 69. Malby RL, Tulip WR, Harley VR, McKimm-Breschkin JL, Laver WG, Webster RG, Colman PM. The structure of a complex between the NC10 antibody and influenza virus neuraminidase and comparison with the overlapping binding site of the NC41 antibody. Structure 1994; 2:733–746. 70. Varghese JN, Webster RG, Laver WG, Colman PM. The three-dimentional structure of an escape mutant of the neuraminidase of influenza virus A/Tokyo/3/67. J Mol Biol 1988; 200:201–203. 71. Weis W, Brown JH, Cusack S, Paulson JC, Skehel JJ, Wiley DC. Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature 1988; 333:426–431. 72. Varghese JN, Epa VC, Colman PM. Three-dimensional structure of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase. Protein Science 1995; 4:1081–1087. 73. Edmond JD, Johnston RG, Kidd D, Rylance HJ, Sommerville RG. The inhibition of neuraminidase and antiviral action. Br J Pharmacol Chemother 1966; 27:415–426. 74. Meindl P, Tuppy H. 2-Deoxy-2,3-dehydrosialic acids. I. Synthesis and properties of 2-deoxy-2,3dehydro-N-acetylneuraminic acids and their methy esters. Monatsh Chem 1969; 100:1295–1306. 75. Meindl P, Bodo G, Palase P, Schulman J, Tuppy H. Inhibition of neuraminidase activity by derivatives of 2-deoxy-2,3-dehydro-N-acetylneuraminic. Virology 1974; 58:457–463. 76. Palase P, Schulman JL, Bodo G, Meidl P. Inhibition of influenza and parainfluenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluroacetylneuraminic acid (FANA). Virology 1974; 59:490–498. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_484.html (1 of 2) [4/9/2004 12:29:15 AM]
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Document 2 Structural Studies of HI
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Document dine) and didanosine (dide
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Document 163. Lacey SF, Larder BA.
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Document Page 108 mulate during tre
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Document We determined the structur
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Document References 1. Parks RE Jr.
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Document 17. Ealick SE, Rule SA, Ca
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Document 6 Structural Implications
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Page 589 and 590: Document Page 476 nM, respectively.
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Page 611 and 612: Document A. The Canyon Page 491 The
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