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Document 89. Plummer MS, Lunney EA, Shahripour A, Para KS, Stankovic CJ, Humblet C, Fergus J, Marks JS, Herrera R, Hubbell SE, Saltiel AR, Sawyer TK. Bioorg Med Chem 1997; 5:41–47. 90. (a) Pert, CB, Synder SH. Science 1973; 179:1011–1014; (b) Lord JA, Waterfield AA, Hughes J, Kosterlitz HW. Nature 1977; 267:495–499. 91. Snider MR, Constantine JW, Lowe JA, Longo KP, Lebel WS, Woody HA, Drozda SE, Desaia MC, Vinick FJ, Spencer RW, Hess H-J. Science 1991; 251:435–437. 92. Chiu AT, McCall DE, Aldrich PE, Timmermans PBMWM. Biochem Biophys Res Commun 1990; 172:1195–1202. 93. Smith RG, Cheng K, Schoen WR, Pong S-S, Hickey G, Jacks T, Butler B, Chan WW-S, Chaung L- YP, Judith F, Taylor J, Wyvratt MJ, Fisher MH. Science 1993; 260:1640–1643. 94. Evans BE, Rittle KE, Bock MG, DiPardo RM, Freidinger RM, Whitter WL, Lundell GF, Veber DF, Anderson PS, Chang RSL, Lotti VJ, Cerno DJ, Chen TB, Kling PJ, Kunkel KA, Springer JP, Hirshfield JJ. J Med Chem 1988; 31:2235–2246. 95. Bock MG, DiPardo RM, Evans BE, Rittle KE, Whitter WL, Veber DF, Andeson PS, Freidinger RM. J Med Chem 1989; 32:13–16. 96. Aquino CJ, Armour DR, Berman JM, Birkemo LS, Carr RAE, Croom DK, Dezube M, Dougherty RW, Ervin GN, Grizzle MK, Head JE, Hirst GC, James MK, Johnson MF, Miller LJ, Queen KL, Rimele TJ, Smith DN, Sugg EE. J Med Chem 1996; 39:562–569. 97. (a) Doherty AM, Patt WC, Edmunds JJ, Berryman KA, Reisdorph BR, Plummer MS, Shahripour A, Lee C, Cheng X-M, Walker DM, Haleen SJ, Keiser JA, Flynn http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_624.html (2 of 2) [4/9/2004 1:45:02 AM]
Document MA, Welch KM, Hallak H, Taylor DG, Reynolds EE. J Med Chem 1995; 38:1259–1263; (b) Doherty AM. Drug Disc Today 1996; 1:60–70. 98. De B, Plattner JJ, Bush EN, Jae H-S, Diaz G, Johnson ES, Perun TJ. J Med Chem 1989; 32:2038–2041. 99. Yamamura Y, Ogawa H, Chihara T, Kondo K, Onogawa T, Nakamura S, Mori T, Tominaga M, Yabuuchi Y. Science 1991; 252:572–574. Page 625 100. Valentine JJ, Nakanishi S, Hageman DL, Snider RM, Spencer RW, Vinick FJ. Bioorg Med Chem Lett 1992; 2:333–338. 101. Collins JL, Dambek PJ, Goldstein SW, Faraci WS. Bioorg Med Chem Lett 1992; 2:915–918. 102. Gully D, Canton MM, Boigegrain R, Jeanjean F, Molimard JC, Poncelete M, Gueudet C, Heaulem M, Leris R, Brouard A, Pelaprat D, Labbe-Jullie C, Mazella J, Soubrie P, Moffrand JP, Rostene W, Kitabji P, Le Fur G. Proc Natl Acad Sci USA 1993; 229:23–28. 103. Perlman S, Schambye HT, Rivero RA, Greenlee WJ, Hjorth SA, and Schwartz TW. J Biol Chem 1995; 270:1493–1496. 104. Evans BE, Leighton JJ, Rittle KE, Gilbert KF, Lundell GF, Gould NP, Hobbs DW, DiPardo RM, Veber DF, Pettitbone DJ, Clineschmidt BV, Anderson PS, Freidinger RM. J Med Chem 1992; 35:3919–3927. 105. Vara Prasad JVN, Para KS, Lunney EA, Ortwine DF, Dunbar JB, Ferguson D, Tummino PJ, Hupe D, Tait BD, Domagala JM, Humblet C, Bhat TN, Liu B, Guerin DMA, Baldwin ET, Erickson JW, Sawyer TK. J Amer Chem Soc 1995; 116:6989–6990. 106. Farmer PS, Ariens EJ. Trends Pharm Sci 1982; 3:362–365. 107. Horwell DC. Approaches to Nonpeptide Ligands for Peptide Receptor Sites. Bioorg Med Chem Lett 1993; 3:No 5. 108. (a) Casey AF. Adv Drug Res 1989; 18:177–289; (b) Portoghese PS. J Med Chem 1992; 35:1927–1937. 109. Wexler RR, Greenlee WJ, Irvin JD, Goldberg MR, Prendergast K, Smith RD, Timmermans PBMWM. J Med Chem 1996; 39:625–656. 110. (a) Doughty MB, Chu SS, Misse GA, Tessel R. Bioorg Med Chem Lett 1992; 2:1497–1502; (b) Chaurasia C, Misse G, Tessel R, Doughty MB. J Med Chem 1994; 37:2242–2248. 111. Nieps S, Michel MC, Dove S, Buschauer A. Bioorg Med Chem Lett 5:2065–2070. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_625.html (1 of 2) [4/9/2004 1:45:46 AM]
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netLibrary - eBook Summary Universi
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Structure-based Drug Design 14 Stru
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Document monophosphate analogs whic
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Document Analysis of various HIV-1
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Document ever, once an NNRTI is bou
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Document Chris Tantillo. The work i
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Document 163. Lacey SF, Larder BA.
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Document Page 96 region in the HIV-
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Document Page 108 mulate during tre
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Document when metals are bound. Fin
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Document cubation of phosphotyrosin
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Document B. Pharmacology Figure 1 T
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Document We determined the structur
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Document large solvent channels and
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Document IV. Drug Design Progressio
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Document Table 1 Inhibition Data fo
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Document References 1. Parks RE Jr.
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Document 6 Structural Implications
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Page 801 and 802: Document site, 52, 55, 61 triad, 24
Page 803 and 804: Document factors, 247 Combination t
Page 805 and 806: Document Cyclotheonamide A (CtA), 2
Page 807 and 808: Document D ddI, 152 tumour necrosis
Page 809 and 810: Document antistasin peptides, 281 c
Page 811 and 812: Document fragment-based programs, 5
Page 813 and 814: Document [Human immunodeficiency vi
Page 815 and 816: Document overview, 103-104, 108-109
Page 817 and 818: Document [Inhibitors] 2-((3,4-dihyd
Page 819 and 820: Document antagonistic activity, 416
Page 821 and 822: Document [Interleukin-1] homology w
Page 823 and 824: Document Kininogen, 119 high molecu
Page 825 and 826:
Document Matrix-metalloproteinase (
Page 827 and 828:
Document RT inhibitor, 41, 56 Nonpe
Page 829 and 830:
Document Phosphoglycerate kinase (P
Page 831:
Document [Protease targets] serinyl
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