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Document 191. (a) Peisach E, Casebier D, Gallion SL, Furth P, Petsko GA, Hogan JC Jr, Ringe D. Science 1995; 269:66–69; (b) Mattos C, Giammona DA, Petsko GA, Ringe D. Biochem 1995; 34:3193–3205; (c) Mattos C, Rasmussen B, Ding X, Petsko G, Ringe D. Nature Struct Biol 1994; 1:55–58. 192. (a) Edwards PD, Bernstein PR. Med Res Rev 1994; 14:127–194; (b) Hiasta DJ, Pagani ED. Ann Rep Med Chem 1994; 29:195–204. 193. Drenth J, Jansonius JN, Koekoek R, Swen HM, Wolthers BG. Nature 1968; 218:929–932. 194. Drenth J, Kalk KH, Swen HM. Biochem 1976; 15:3731–3738. 195. Schroeder E, Phillips C, Gaman E, Harlos K, Crawford C. FEBS Lett 1993; 315:38–42. 196. Rauber P, Angliker H, Walker B, Shaw E. Biochem J 1986; 239:633–640. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_630.html (2 of 2) [4/9/2004 1:48:30 AM]
Document Page 631 197. Musil D, Zucic D, Turk D, Engh RA, Mayr I, R Huber Popovic T, Turk V, Towatari T, Katunuma N, Bode W. EMBO J 1991; 10:2321–2330. 198. (a) Allair M, Chernaia M, Malcolm BA, James MNG. Nature 1994; 369:72–77; (b) Matthews DA, Smith WW, Ferre RA, Condon B, Budahazi G, Sisson W, Villafranca JE, Janson CA, McElroy HE, Gribskow CL, Worland S. Cell 1994; 77:761–771. 199. Wilson KP, Black JF, Thomson JA, Kim EE, Griffith JP, Navia MA, Murcko MA, Chambers SP, Aldape RA, Raybuck SS, Livingson DJ, Nature 1994; 370:270–275. 200. Walker NPC, Talanian RV, Brady KD, Dang LC, Bump NJ, Ferenz CR, Franklin S, Ghayur T, Hackett MC, Hammill LD, Herzog L, Hugunin M, Houy W, Mankovich JA, McGuiness L, Orlewicz E, Paskind M, Pratt CA, Reis P, Summani A, Terranova M, Welch JP, Xiong L, Moller A, Tracey DE, Kamen R, Wong WW. Cell 1994; 78:343–352. 201. Ator MA, Dolle RE. Curr Pharm <strong>Design</strong> 1995; 1:191–210. 202. Mullikan MD, Lauffer DJ, Gillespie RJ, Matharu SS, Kay D, Porritt GM, Evans PL, Golec JMC, Murcko MA, Luong Y-P, Raybuck SA, Livingston DJ. Bioorg Med Chem Lett 1994; 4:2359–2364. 203. Dole RE, Singh J, Rinker J, Hoyer D, Prasad CVC, Graybill TL, Salvino JM, Helaszek CT, Miller RE, Ator MA. J Med Chem 1994; 37:3863–3866. 204. Dole RE, Prouty CP, Prasad CVC, Cook E, Saha A, Morgan Ross T, Salvino JM, Helaszek CT, Ator MA. J Med Chem 1996; 39:2438–2440. 205. Rotonda J, Nicholson DW, Fazil KM, Gallant M, Gareau Y, Labelle M, Peterson EP, Rasper DM, Ruel R, Vaillancourt JP, Thornberry NA, Becker JW, Nature (Struct Biol) 1996; 3:619–625. 206. Matthews BW. Acc Chem Res 1988; 21:333–340. 207. (a) Matthews BS, Jansonius JN, Colman PM, Schoenborn B, Dupourque D. Nature (London) New Biol 1972; 238:37–41; (b) Holmes MA, Matthews BW. J Mol Biol 1982; 160:623–639. 208. Weaver LH, Kester WR, Matthews BW. J Mol Biol 1977; 114:119–132. 209. (a) Holden HM, Tronrud DE, Monzingo AF, Weaver LH, Matthews BW. Biochem 1987; 26:8542; (b) Bartlett PA, Marlowe CK. Biochem 1987; 26:8553–8561. 210. (a) Montzingo AR, Matthews BW. Biochem 1984; 23:5724-; (b) Maycock AL, DeSousa DM, Payne LG, ten Broeke J Wu MT, Patchett AA. Biochem Biophys Res Commun 1981; 102:963–969. 211. (a) Holmes MA, Matthews BW, Biochem 1981; 20:6912; (b) Nishino N, Powers JC. Biochem 1978; 17:2846–2850. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_631.html (1 of 2) [4/9/2004 1:48:58 AM]
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Structure-based Drug Design 14 Stru
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Document Page 108 mulate during tre
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Page 819 and 820: Document antagonistic activity, 416
Page 821 and 822: Document [Interleukin-1] homology w
Page 823 and 824: Document Kininogen, 119 high molecu
Page 825 and 826: Document Matrix-metalloproteinase (
Page 827 and 828: Document RT inhibitor, 41, 56 Nonpe
Page 829 and 830: Document Phosphoglycerate kinase (P
Page 831: Document [Protease targets] serinyl
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