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Document 150. (a) Cooper JB, Foundling SI, Watson FI, Sibanda BL, Blundell TL. Biochem Soc Trans 1987; 15:751–754; (b) Cooper JB, Foundling SI, Hemmings A, Blundell TL, Jones DM, Hallett A, Szelke M, Eur J Biochem 1987; 169:215–21; (c) Hallett A, Jones DM, Atrash B, Szelke M, Leckie B, Beattle S, Dunn BM, Valler MJ, Rolph CE, Jay J, Foundling SI, Wood S, Pearl LH, Watson FE, Blundell TL. In: Kostka V., Ed. Aspartic Proteinases and Their Inhibitors. Berlin: de Gruyter, (1985); 467–478; (d) Sali A, Veerapandian B, Cooper JB, Foundling SI, Hoover DJ, Blundell TL. EMBO J 1989; 2179–2188; (e) Veerapandia B, Cooper JB, Sali A, Blundell TL. J Mol Biol 1990; 216:1017–1029; (f) Suguna K, Padlan EA, Smith CW, Carlson WD, Davies DR, Proc Natl Acad Sci USA 1987; 84:7009–7013; (g) Abad- Zapatero C, Rydel TJ, Neidhart DJ, Luly J, Erickson JW, Adv Exp http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_627.html (2 of 2) [4/9/2004 1:47:10 AM]
Document Med Biol 1991; 306:9–21; (h) James MN, Sielecki AR, Hayakawa K, Gelb MH. Biochem 1992; 31:387. Page 628 151. (a) Sielecki AR, Hayakawa K, Fujinaga M, Murphy ME, Fraser M, Muir AK, Carilli CT, Lewicki JA, Baxter JD, James, MN. Science 1989; 243:1346–1351; (b) Rahuel J, Priestle JP, Grutter MG. J Struct Biol 1991; 107:227–236. 152. Plummer MS, Shahripour A, Kaltenbronn JS, Lunney EA, Steinbaugh BA, Hamby JM, Hamilton HW, Sawyer TK, Humblet C, Doherty AE, Taylor MD, Hingorani G, Batley BL, Rapundalo ST. J Med Chem 1995; 38:2893–2905. 153. Rasetti V, Cohen NC, Rueger H, Boschke R, Maibaum J, Cumin F, Fuhrer W, Wood JM. Bioorg Med Chem Lett 1996; 6:1589–1594. 154. Weber AE, Halgren TA, Doyle JJ, Lynch RJ, Siegel PKS, Parsons WH, Greenlee WJ, Patchett AA. J Med Chem 1991; 34:2692–2701. 155. (a) Dutta AS, Gormely JJ, McLachlan PF, Major JS. J Med Chem 1990; 33:2552–2560; (b) Dutta AS, Gormley JJ, McLachlan PF, Major JS. J Med Chem 1990; 33:2560–2568. 156. (a) Kempf J, Sham HL. Curr Pharm Design 1996; 2:225–246; (b) Wlodawer A, Erickson JW. Ann Rev Biochem 1993; 62:543–585; (c) Appelt K. Perspect Drug Disc Design 1993; 1:23–48; (d) Meek TD. J Enz Inhib 1992; 6:65–98 (e); Tomasselli AG, Howe WJ, Sawyer TK, Wlodawer A, Heinrikson RL. Chim Oggi 1991; 9:6–27; (f) Huff JR. J Med Chem 1991; 34:2305–2314. 157. (a) Erickson J, Neidhart DJ, VanDrie J, Kempf DJ, Wang XC, Norbeck DW, Plattner JJ, Rittenhouse JW, Turon M, Wideburg N, Kohlbrenner WE, Simmer R, Helfrich R, Pau DA, Knigge M, Science 1990; 249:529–533; (b) Kempf DJ, Norbeck DW, Codacovi L, Wang XC, Kohlbrenner WE, Wideburg NE, Paul DA, Knigge MF, Vasavanonda S, Criag-Kennard A, Saldivar A, Rosenbrook JW, Clement JJ, Plattner JJ, Erickson J. J Med Chem 1990; 33:2687–2689. 158. Lam PYS, Jadhav PK, Eyermann CJ, Hodge CN, Ru Y, Bacheler LT, Meek JL, Otto MJ, Rayner MM, Wong YN, Chang C-H, Weber PC, Jackson DA, Sharpe TR, Erickson-Viitanen S. Science 1994; 263:380–383. 159. Kempf DJ, March KC, Denissen JF, McDonald E, Vasavanonda S, Flentge CA, Green BE, Fino L, Park CH, Kong X-P, Wideburg NE, Saldivar A, Ruiz A, Kati WM, Sham HL, Robins T, Stewart KD, Hsu A, Plattner JJ, Leonard JM, Norbeck DW. Proc Natl Acad Sci USA 1995; 92:2484–2488. 160. Vacca JP, Dorsey BD, Schlief WA, Levin RB, McDaniel SL, Darke PL, Zugay J, Quintero JC, Blahy OM, Roth E, Sardana VV, Schlabach AJ, Graham PI, Condra JH, Gotlib L, Holloway MK, Lin J, Chen I-W, Vastag K, Ostovic D, Anderson PS, Emini EA, Huff JR. Proc Natl Acad Sci USA 1994; 91:4096–4100. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_628.html (1 of 2) [4/9/2004 1:47:40 AM]
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Structure-based Drug Design 14 Stru
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Page 805 and 806: Document Cyclotheonamide A (CtA), 2
Page 807 and 808: Document D ddI, 152 tumour necrosis
Page 809 and 810: Document antistasin peptides, 281 c
Page 811 and 812: Document fragment-based programs, 5
Page 813 and 814: Document [Human immunodeficiency vi
Page 815 and 816: Document overview, 103-104, 108-109
Page 817 and 818: Document [Inhibitors] 2-((3,4-dihyd
Page 819 and 820: Document antagonistic activity, 416
Page 821 and 822: Document [Interleukin-1] homology w
Page 823 and 824: Document Kininogen, 119 high molecu
Page 825 and 826: Document Matrix-metalloproteinase (
Page 827 and 828: Document RT inhibitor, 41, 56 Nonpe
Page 829 and 830: Document Phosphoglycerate kinase (P
Page 831:
Document [Protease targets] serinyl
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