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Document 30. Pevear DC, Fancher MJ, Felock PJ, et al. Conformational change in the floor of the human rhinovirus canyon blocks adsorption to HeLa cell receptors. J Virol 1989; 63:2002–2007. 31. Lonberg-Holm K, Korant BD. Early interaction of rhinoviruses with host cells. J Virol 1972; 9:29–40. 32. Korant BD, Lonberg-Holm K, Yin FH, Noble-Harvey J. Fractionation of biologically active and inactive populations of human rhinovirus type 2. Virology 1975; 63:384–394. Page 521 33. Everaert L, Vrusen R, Boeye A. Eclipse products of poliovirus after cold-synchronized infection of HeLa cells. Virology 1989; 171:76–82. 34. Hooverlitty H, Greve JM. Formation of rhinovirus-soluble ICAM-1 complexes and conformational changes in the virion. J Virol 1993; 67(1):390–397. 35. Neubauer C, Frasel L, Kuechler E, Blaas D. Mechanism of entry of human rhinovirus 2 into HeLa cells. Virology 1987; 158:255–258. 36. Zeichhardt H, Wetz K, Willingmann P, Habermehl KO. Entry of poliovirus type 1 and mouse elberfeld (ME) virus into HEp-2 cells: receptor mediated endocytosis and endosomal or lysosomal uncoating. J Gen Virol 1985; 66:483–492. 37. Gromier M, Wetz K. Kinetics of poliovirus uncoating in HeLa cells in a nonacidic environment. J Virol 1990; 68(8):3590–3597. 38. Madshus IH, Olsnes S, Sandvig. Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH. J Cell Biol 1984; 98:1194–1200. 39. Madshus IH, Olsnes S, Sandvig K. Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus. Virology 1984; 139:346–357. 40. Perez L, Carrasco L. Entry of poliovirus into cells does not require a low-pH step. J Virol 1993; 67(8):4543–4548. 41. Giranda VL, Heinz BA, Oliveira MA, et al. Acid-induced structural changes in human rhinovirus- 14—possible role in uncoating. Proc Natl Acad Sci USA 1992; 89(21):10213–10217. 42. Skern T, Torgersen H, Auer H, Kuechler E, Blaas D. Human rhinovirus mutants resistant to low pH. Virology 1991; 183:757–763. 43. Alber T, Dao-pin S, Nye JA, Muchmore DC, Matthews BA. Temperature-sensitive mutations of bacteriophage T4 lysozyme occur at sites with low mobility and low solvent accessibility in the folded protein. Biochemistry 1987; 26:3754–3758. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_521.html (1 of 2) [4/9/2004 12:45:56 AM]
Document 44. Argos P, Rossmann MG, Grau UM, Zuber H, Frank G, Tratschin JD. Thermal stability and protein structure. Biochemistry 1979; 18:5698–5703. 45. Matthews BA. Genetic and structural analysis of the protein stability Problem. Biochemistry 1987; 26:6885–6888. 46. Perutz MF, Raidt H. Stereochemical basis of heat stability in bacterial ferredoxins and in haemoglobin A2. Nature 1975; 255:256–259. 47. Gruenberger M, Pevear D, Diana GD, Kuechler E, Blaas D. Stabilization of human rhinovirus serotype 2 against pH-induced conformational change <strong>by</strong> antiviral compounds. J Gen Virol 1991; 72:431–33. 48. Fricks CE, Hogle JM. Cell-induced conformational change in poliovirus: Externalization of the amino terminus of VP1 is responsible for liposome binding. J Virol 1990; 64:1934–1945. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_521.html (2 of 2) [4/9/2004 12:45:56 AM]
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netLibrary - eBook Summary Universi
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Structure-based Drug Design 14 Stru
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Document 2 Structural Studies of HI
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Document 163. Lacey SF, Larder BA.
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Document Page 108 mulate during tre
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Document receptor, it has not yet b
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Document We determined the structur
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Document Figure 3 Previously known
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Document large solvent channels and
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Document IV. Drug Design Progressio
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Document Page 166 As predicated, th
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Document References 1. Parks RE Jr.
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Document 6 Structural Implications
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Document Important for the validity
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Document Figure 4 Amino acids impor
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Document 17 Structure and Functiona
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Document Table 1 Approval Indicatio
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Document Page 438 proteins. One pot
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Document Page 462 strains of influe
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Document B. Protein Structure Page
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Document Page 476 nM, respectively.
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Document VI. Conclusion Page 480 It
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Page 601 and 602: Document 64. Ward CW, Elleman TC, A
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Page 605 and 606: Document Page 486 95. Ryan DM, Tice
Page 607 and 608: Document Page 488 against most of t
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Page 613 and 614: Document Subsequent studies have sh
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Page 617 and 618: Document Figure 4 A ribbon diagram
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Page 639 and 640: Document conformational transition
Page 641 and 642: Document Page 518 The differences b
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Page 685 and 686: Document Lists of Bonding Fragment
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Page 689 and 690: Document Page 555 N-acylpyrrolidine
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Document Acknowledgments Page 620 I
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Document 18. Sawyer TK. In: Peptide
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Document Med Biol 1991; 306:9-21; (
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Document Page 629 ML, Clare M, Decr
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Document Page 631 197. Musil D, Zuc
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Document son AH, Drummond AH, Huxle
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Document factors, 247 Combination t
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Document Cyclotheonamide A (CtA), 2
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Document D ddI, 152 tumour necrosis
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Document antistasin peptides, 281 c
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Document fragment-based programs, 5
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Document [Human immunodeficiency vi
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Document Phosphoglycerate kinase (P
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Document [Protease targets] serinyl
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