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Document 112. (a) Williams PD, Ball RG, Clineschmidt BV, Culberson JC, Erb JM, Freidinger RM, Pawluczyk JM, Perlow DS, Pettibone DJ, Veber DF. J Med Chem 1994; 2:971–985; (b) Williams PD, Anderson PS, Ball RG, Bock MG, Carroll LA, Lee Chiu S-H, Clineschmidt BV, Culberson JC, Erb JM, Evans BE, Fitzpatrick SL, Freidinger RM, Kaufman MJ, Lundell GF, Murphy JS, Pawluczyk JM, Perlow DS, Pettibone DJ, Pitzenberger SM, Thompson KL, Veber DF. J Med Chem 1994; 37:565–571. 113. Greer J, Erickson JW, Baldwin JJ, Varney MD. J Med Chem 1994; 37:1035–1054. 114. Colman PM. Curr Opinion Struct Biol 1994; 4:868–874. 115. (a) Verlinde LMJ, Hol WGJ. Structure 1994; 2:577–587; (b) Hol WGJ. Angew Chemie 1986; 25:767–852. 116. Navia MA, and Murcko MA. Curr Opinion Struct Biol 1992; 2:202–210. 117. Appelt K, Bacquet RJ, Barlett CA, Booth CLJ, Freer ST, Fuhry MA, Gehring MR, Herrmann SM, Howland EF, Janson CA, Jones TR, Kan C-C, Kathardekar V, Lewis KK, Marzoni GP, Matthews DA, Mohr C, Moowaw EW, Morse CA, Oatley http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_625.html (2 of 2) [4/9/2004 1:45:46 AM]
Document Page 626 SJ, Ogden RC, Reddy M, Reich SH, Schoettlin WS, Smith WW, Varney MD, Villafranca JE, Ward RW, Webber S, Webber SE, Welsch KM, White J. J Med Chem 1991; 34:1925–1934. 118. Marshall GR. Curr Opinion Struct Biol 1992; 2:904–919. 119. Veerapandian P. In: Burger's Medicinal Chemistry and Drug Discovery. Fifth Ed. Vol. 1 (Wolff ME, Ed) Wiley and Sons Inc. 1995; 303–348. 120. (a) Kuntz ID. Science 1992; 237:1078–1082; (b) Roe D, Kuntz ID. Pharm News 1995; 2:13–15. 122. Fong TM, Strader CD. Med Res Rev 1994; 14:387–399. 121. Ajay Murko MA. J Med Chem 1995; 38:4973–4967. 123. (a) Schwartz TW, Gether U, Schamby HT, Hjorth SA. Curr Pharm Design 1995; 1:355–372; (b) Schwartz TW. Curr Opinion Biotech 1994; 5:434–444. 124. Humblet C, Mirzadegan T. Ann Rep Med Chem 1992; 27:291–300. 125. Findley J, Eliopoulos E. Trends Pharm Sci 1990; 11:492–499. 126. (a) Hilbert MF, Trumpp-Kallmeyer S, Hoflack J, Bruinvels A. Trends Pharm Sci 1993; 14:7–12; (b) Trumpp-Kallmeyer S, Hoflack J, Bruinvels A, Hilbert M. J Med Chem 1992; 35:3448–3462; and (c) Hilbert MF, Trumpp-Kallmeyer S, Bruinvels A, Hoflack J. Molec Pharmacol 1991; 40:8–15. 127. Kontoyianni M, Lybrand TP. Med Chem Res 1993; 3:407–418. 128. Probst WC, Snyder LA, Schuster DI, Brosius J, Sealfon SC. DNA Cell Biol 1992; 11:1–20. 129. Moereels H, Jannsen PAJ. Med Chem Res 1993; 3:335–343. 130. Attwood TK, Findlay JBC. Prot Eng 1994; 7:195–203. 131. Savares TM, Fraser CM. Biochem J 1992; 283:1–19. 132. Brann MR. Molecular Biology of G-Protein-Coupled Receptors, Boston: Birkhauser, 1992. 133. Henderson R, Baldwin JM, Ceska TA, Semlin F, Beckman E, Downing KH. J Mol Biol 1990; 213:899–929. 134. (a) Underwood DJ, Strader CD, Rivero R, Patchett A, Greenlee W, Pendergrast K. Chem Biol 1994; 1:211–221; (b) Schambye HT, Hjorth SA, Bergsama DJ, Sathe G, Schwartz TW. Proc Natl Acad Sci USA 1994; 91:7046–7050; (c) Yamano Y, Ohyama K, Chaki S, Guo D-F, Inagami T. Biochem Biophys Res Comm 1992; 187:1426–1431; (d) Yamano Y, Ohyama K, Kikyo M. J Biol Chem 1995; 270:14024–14030. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_626.html (1 of 2) [4/9/2004 1:46:39 AM]
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Structure-based Drug Design 14 Stru
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Page 825 and 826: Document Matrix-metalloproteinase (
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Document RT inhibitor, 41, 56 Nonpe
Page 829 and 830:
Document Phosphoglycerate kinase (P
Page 831:
Document [Protease targets] serinyl
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