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Document 248. Hatada MH, Lu X, Laird ER, Green J, Morgenstern JP, Lou M, Marr CS, Phillips TB, Ram MK, Theriault K, Zoller MJ, Karas JL. Nature 1995; 377:32–38. 249. (a) Yu H, Rosen MK, Shin TB, Seidel-Dugan C, Brugge JS, Schreiber SL. Science 1992; 258:1655–1668; (b) Feng S, Chen JK, Yu H, Simon JA, Schreiber SL. Science 1994; 266:1241–1247. 250. Musacchio A, Saraste M, Wilmann M. Nature (Struct Biol) 1994; 1:546–551. 251. Wu X, Knudsen B, Feller SM, Zheng J, Sali A, Cowburn D, Hanafusa H, Kuriyan J. <strong>Structure</strong> 1995; 3:215–226. 252. Goudreau N, Cornille F, Duchesne M, Parker F, Tocque B, Garbay C, Roques BP. Nature (Struct Biol) 1994; 1:898–907. 253. Maignan S, Guilloteau J-P, Fromage N, Arnoux B, Becquart J, Ducruix A. Science 1995; 268:291–293. 254. Hubbard SR, Wei L, Ellis L, Hendrickson WA. Nature 1994; 372:746–754. 255. (a) Zheng J, Knighton DR, Xuong H-H. Taylor SS, Sowadski JM, Ten Eyck LF. Protein Sci 1993; 2:1559–1573; (b) Karlsson R, Zheng J, Xuong N-H, Taylor SS, Sowadski JM. Acata Crystallogr 1993; D49:381–388. 256. (a) De Bondt HL, Rosenblatt J, Jancarik J, Jones HD, Morgan DO, Kim SH. Nature 1993; 363:595–02; (b) Russo AA, Jeffrey PD, Patten AK, Massague J, Pavletich NP. Nature 1996; 38:325–331. http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_633.html (2 of 3) [4/9/2004 1:50:03 AM]
Document http://legacy.netlibrary.com/nlreader/nlReader.dll?bookid=12640&filename=Page_633.html (3 of 3) [4/9/2004 1:50:03 AM] 257. Zhang F, Strand A, Robbins D, Cobb MH, Goldsmith EJ. Nature 1994; 367:704–710.
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Structure-based Drug Design 14 Stru
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Document 2 Structural Studies of HI
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Document Page 54 Table 2) [12,54].
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Document Table 3 HIV-1 RT Amino Aci
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Document 106. Cirino NM, Cameron CE
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Document 122. Marshall WS, Beaton G
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Document dine) and didanosine (dide
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Document 163. Lacey SF, Larder BA.
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Document Page 108 mulate during tre
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Document 4 Bradykinin Receptor Anta
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Document Table 1 Inhibition Data fo
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Document References 1. Parks RE Jr.
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Document 6 Structural Implications
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Document Important for the validity
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Document Figure 4 Amino acids impor
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Document III. Results and Discussio
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Document Page 202 269, and valine-2
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Document Figure 6 Structure of α h
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Document Page 205 enzyme and of phe
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Document Page 438 proteins. One pot
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Document Page 462 strains of influe
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Document B. Protein Structure Page
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Document Page 495 of the RNA and pr
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Page 761 and 762: Document Page 617 Val (131) showed
Page 763 and 764: Document Figure 32 PTP and PTB 3D s
Page 765 and 766: Document Acknowledgments Page 620 I
Page 767 and 768: Document 18. Sawyer TK. In: Peptide
Page 769 and 770: Document Page 622 Fukuroda T, Fukam
Page 771 and 772: Document Page 623 53. Bird J, Harpe
Page 773 and 774: Document 78. Rodriguez M, Crosby R,
Page 775 and 776: Document MA, Welch KM, Hallak H, Ta
Page 777 and 778: Document Page 626 SJ, Ogden RC, Red
Page 779 and 780: Document 97; (e) Fujii I, Nakamura
Page 781 and 782: Document Med Biol 1991; 306:9-21; (
Page 783 and 784: Document Page 629 ML, Clare M, Decr
Page 785 and 786: Document Page 630 177. (a) Bode W,
Page 787 and 788: Document Page 631 197. Musil D, Zuc
Page 789 and 790: Document son AH, Drummond AH, Huxle
Page 791: Document 236. (a) Marshall MS. TIBS
Page 795 and 796: Document 274. (a) Kavanaugh WM, Wil
Page 797 and 798: Document replacements, 563-565 1-am
Page 799 and 800: Document inhibitor binding, 323, 33
Page 801 and 802: Document site, 52, 55, 61 triad, 24
Page 803 and 804: Document factors, 247 Combination t
Page 805 and 806: Document Cyclotheonamide A (CtA), 2
Page 807 and 808: Document D ddI, 152 tumour necrosis
Page 809 and 810: Document antistasin peptides, 281 c
Page 811 and 812: Document fragment-based programs, 5
Page 813 and 814: Document [Human immunodeficiency vi
Page 815 and 816: Document overview, 103-104, 108-109
Page 817 and 818: Document [Inhibitors] 2-((3,4-dihyd
Page 819 and 820: Document antagonistic activity, 416
Page 821 and 822: Document [Interleukin-1] homology w
Page 823 and 824: Document Kininogen, 119 high molecu
Page 825 and 826: Document Matrix-metalloproteinase (
Page 827 and 828: Document RT inhibitor, 41, 56 Nonpe
Page 829 and 830: Document Phosphoglycerate kinase (P
Page 831: Document [Protease targets] serinyl
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