Rapporten - SBU

Table 3.1.16 RAADS-R.
Author
Year
Reference
Country
Ritvo et al
2011
[5]
USA
Aim Study design
Population characteristics
Setting
Disease prevalence
Drop-out
To standardize
the RAADS-R
Study design
Case-control
Population characteristics
N=779
ASD: n=201 (AD: n=66,
AS: n=135)
Comparisons n=578
(no diagnosis n=276 other
DSM-IV-TR diagnosis n=302)
Age range: 30.4–42.04 years
Mean IQ range: 112–122
Gender: 44.4% male
Setting
9 research centers
on 3 continents
(university clinics)
Disease prevalence
ASD: 26%
Drop-out
Not reported
126 Autismspektrumtillstånd – diAgnostik och insAtser,
KAPITEL 3 • sysTEmATIsK LITTErATurövErsIKT –
127
vårdens orgAnisAtion och pAtientens delAktighet
Index test Reference
test
RAADS-R
A RAADS-R score
of 65 or greater is
consistent with a
clinical diagnosis
of ASD
A RAADS-R score
of 65 or lower is
not consistent with
a clinical diagnosis
of ASD
AS = Aspergers syndrome; ASD = Autism spectrum disorder; DSM-IV-TR = Diagnostic
and statistical manual of mental disorders, fourth edition, text revision; IQ = Intelligence
quotient; N = Number of patients; RAADS-R = Ritvo autism Asperger diagnostic scale
revised; Se = Sensitivity; Sp = Specificity
All ASD
subjects
met a clinical
DSM-IV-TR
diagnosis of
autism or AS
Main findings Study quality Comments
ASD vs non-ASD
Se: 0.97
Sp: 1.00
InsTrumEnT för uTrEdnIng Av AsT
Moderate Limitations: There were
significant differences of
the mean RAADS scores
among the 9 research
centers
The subjects were given
the RAADS-R to comp-
lete in the presence of a
clinician who introduced
the instrument and
offered clarifications
when needed. The
clinician was blinded to
diagnostic information