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joint strategic needs assessment foundation profile - JSNA

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Interative Hull Atlas: www.hullpublichealth.org/Pages/hull_atlas.htm More information: www.jsnaonline.org and www.hullpublichealth.org<br />

specific time period. Direct standardisation results in an age-gender standardised rate<br />

of disease (often per 10,000 or 100,000 population).<br />

Indirect standardisation generally 71 results in a standardised mortality (or morbidity) ratio<br />

(SMR). The SMR will take the value of 100 if the sample group has the same mortality<br />

(or morbidity) rate as the „standard‟ population, and an SMR greater (less) than 100 if<br />

the sample group has a greater (lower) mortality rate relative to the standard population.<br />

An SMR of 130 means that there is a 30% higher mortality rate for people in the local<br />

area compared to England even after taking into account the gender and age structure<br />

of the two geographical areas. An SMR of 80 means that the mortality rate locally is<br />

80% of that observed nationally after allowing for differences in the gender and age<br />

structure of the two areas (or equivalently 20% lower locally compared to the standard<br />

population).<br />

12.4 Significance Testing<br />

It is often useful to compare a particular summary parameter (for instance, mean,<br />

median, measure of risk) among different groups. Since there is natural variation<br />

associated with virtually all measurements and since we generally only have a sample<br />

and have not measured the entire population, it is necessary to distinguish between<br />

differences which are close enough together to be explained by chance and differences<br />

which are „unlikely‟ to be explained by chance. Such a comparison can be undertaken<br />

using a statistical test which takes into the account chance variation. When undertaking<br />

a statistical test, we assume that there is no difference in the summary measure among<br />

the groups and then calculate the probability of obtaining the difference we observe in<br />

our sample (i.e. in the data we have). If the calculated probability, or so-called p-value,<br />

is small then this means that there is a small chance of obtaining such a result under the<br />

assumption that there is no difference. Therefore, if the probability is small enough<br />

(generally, less than one in twenty or less than 0.05) then we assume that the original<br />

assumption must be incorrect and that there really is a difference. Since this is based<br />

on probabilities and assumptions, just because a small p-value is observed, it does not<br />

necessarily mean that the original assumption of no difference between the groups is<br />

untrue. However, clearly the smaller the p-value, the more likely it is that the original<br />

assumption is untrue. Similarly, just because you obtain a large p-value and therefore<br />

have no evidence to reject the original assumption, it does not mean that it is actually<br />

true, it could be that there is simply insufficient evidence to show otherwise (for example,<br />

a small number of people or small number of people with a particular event). If a small<br />

p-value is obtained (p

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