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Introduction<br />

The European Commission Concerted Action FAIR CT97-3233 was set up in 1997 following<br />

the publication of several scientific papers showing a possible role of lycopene in the<br />

prevention of diseases such as cancer and cardiovascular diseases. Epidemiological studies<br />

showed that these risks increased with low tomato consumption, the main source of lycopene.<br />

A consortium of 15 tomato research institutes and tomato processors from all around Europe<br />

was formed, with funding from the European Commission within the framework of the FAIR<br />

RTD programme, to review the scientific literature available in order to produce a "white<br />

book" on the antioxidants in tomatoes and tomato products. This data would help the industry<br />

improve the nutritional quality of the tomato-based products and the scientists to understand<br />

better the relationship between nutrition and health.<br />

The researchers were organised into 4 working group to study different aspects:<br />

• Working Group 1 : Composition of tomatoes and tomato products in antioxidants<br />

(methods of analysis; breeding and biotechnology to increase the antioxidant content;<br />

evolution of the composition during ripening and storage), chaired by Dr. Pascal Grolier<br />

(INRA, Clermont-Ferrand, France)<br />

• Working Group 2 : Processing and bioavailability (effects of mechanical and thermal<br />

treatments and storage conditions on the antioxidants content and their bioavailability),<br />

chaired by Dr. Carlo Leoni (SSICA, Italy)<br />

• Working Group 3 : Epidemiological observational studies (protection offered by<br />

antioxidants on cardiovascular diseases, cancer and ageing), chaired by Dr. Mariette Gerber<br />

(INSERM-CRLC, Montpellier, France)<br />

• Working Group 4 : Mechanisms and biomarkers (mechanisms involved in the<br />

protection and biomarkers), chaired by Prof. Rod Bilton (Liverpool John Moores University,<br />

UK).<br />

Project management and co-ordination were provided by Prof. Gérard Bartholin (CTCPA,<br />

Avignon, France), Mr. Bernard Bièche & Mrs Sophie Colvine (AMITOM, Avignon, France).

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