NO - Besoin d'assistance

Table 40 Vitamin C and cataract
Observational epidemiological surveys (WG 3) page 71
_________________________________________________________________________________________
Authors, year and number of
subjects
Odds ratio and CI Comments
Jacques and Chylak, 1991 (n = 112) high (>90 µmol/L) vs low plasma vitamin c (< 40 after adjustment on age, sex, race and
µmol/L)
0.29 (0.06 - 1.32); ns
Jacques and Chylak, 1991 (n = 112) early cataract
higher (> 490 mg/d) vs lower vitamin C intake (< 125
mg/d); 0.25 (0.06 - 1.29); ns
history of diabetes
Robertson et al., 1989 (n = 304) advanced cataract
higher (> 300 mg/d) vs no vitamin C intake as
supplements; 0.30 (0.24 - 0.77); P 294 mg/d; n= 165) vs lower vitamin C intake (<
77 mg/d; n= 136); 0.27 (0.11 - 0.67)
women consumed vit. C for >10 years
Mares-Perlman et al., 1994, (n = nuclear cataract
past use of supplements containing vit. C;
1980)
0.7 (0.5 - 1.0)
cortical cataract
1.8 (1.2 - 2.9)
age, sex smoking & alcohol consumption
Mohan et al., 1989 (n = 1990) mixed cataract
1.87 (1.29 - 2.39)
plasma vit C concentration
Vitale et al., 1994 (n = 671) nuclear cataract
1.31 (0.61 - 2.39)
high (>80 µmol/L) vs low plasma Vit. C (< 60 µmol/L)
cortical cataract
1.01 (0.45 -2.26)
age, sex and diabetes
Lyle et al., 1999a (n=1349) high intake (281mg/kcal) vs low 27)
smokers 0.3 (0.1-0.8) trend 0.01
Beaver Dam Eye Study
0.8 (0.5-1.4) trendNS
hypertension: 0.3 (0.1-0.8) trend 0.02