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Table 39 Age related macular degeneration<br />

Authors, year and number of<br />

subjects<br />

Eye Disease Cas-Control Study,<br />

1993, (n = 390)<br />

Observational epidemiological surveys (WG 3) page 69<br />

_________________________________________________________________________________________<br />

Odds ratio and CI Comments<br />

Carotenoids<br />

neovascular AMD<br />

low group 0.88 µmol/L blood bcarotene<br />

0.3 (0.2 - 0.6)<br />

West et al., 1994, (n = 226) β-carotene in the blood<br />

High (>0.88 µmol/l) vs low group<br />

(< 0.34 µmol/l)<br />

0.62 (0.36 - 1.07)<br />

Eye Disease Cas-Control Study,<br />

1993, (n = 390)<br />

Vitamin C<br />

Middle vs low group<br />

low group 90.8 µmol/L.<br />

0.60 (0.4 - 0.9)<br />

West et al., 1994, (n = 226) High (>82 µmol/l) vs low group (<<br />

59.6 µmol/l)<br />

0.55 (0.28 - 1.08)<br />

Eye Disease Cas-Control Study,<br />

1993, (n = 390)<br />

Vitamin E<br />

Middle vs low group (no<br />

improvement in high group)<br />

low group 43.4 µmol/L.<br />

0.6 (0.4 - 0.9)<br />

West et al.; 1994, (n = 226) High (>82 µmol/l) vs low group (<<br />

18.6 µmol/l)<br />

0.43 (0.25 - 0.73)<br />

Lut-zea, β-car, sum of all, same<br />

odds ratio

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