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Observational epidemiological surveys (WG 3) page 59
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Table 33 Prospective studies on dietary intake of vitamin E
Authors
(year)
Kushi et al.,
(1996)
Iowa women's
health study
Knekt et al.,
(1994)
Finnish mobile
clinic study
Stampfer et al.,
(1993)
Nurses Health
Study
Rimm et al.,
(1993)
Male Health
Professionals
Study
Klipstein-
Grobusch et al.
(1999) The
Rotterdam study
Yochum et al.
(2000)
The Iowa
Women’s
Health Study
country
n cases
M or F, age
(Follow-up
duration)
Iowa PM women
34 486
F, 55-69
7 yr
Finland
2748 M, 30-69
2385 F, 30-69
US nurses
87 245
F, 34-59
8 yr
Male health
professionals
39 910
M, 40-75
4 yr
Netherlands
124 (4802 elderly,
aged 55-95)
34492 postmenopausal
women
baseline 1986,
outcome exposure
measurement
Deaths from
CHD
Incidence of
CHD deaths
Non-fatal MI
Deaths from
CHD
Non-fatal MI
Deaths from
CHD
MI
(elderly)
Dietary intakes +
supplements by Willett FFQ
OR, comparison
group, CI, P trend
T5/1 OR=0.38.(0.18-0.80)
(food)
OR=1.09 (0.67-1.77) (suppl)
OR=0.96 (0.62-1.51) (food
+ suppl)
Intakes by FFQ In women only:
OR=0.35 (0.14-0.88)
Dietary intake by Willett
FFQ
Dietary intake by Willett
FFQ
stroke Dietary intakes +
supplements by Willett FFQ
T5/1 OR=0.66 (0.50-0.87)
For greater than 2 yr use of
suppl: OR = 0.59 (0.38-
0.91)
T5/1
OR for 7.5 IU vit E
= 0.64 (0.49-0.83)
FFQ OR= 121
(0.75 to 1.98)
P trend NS
H(238mg/day) vs L(4.9)
0.91 (0.55-1.52
trend NS
Remarks
In non-supplement users, vit E
intakes inversely related to CHD
deaths; overall trend, P