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Observational epidemiological surveys (WG 3) page 25<br />

_________________________________________________________________________________________<br />

Table 12: Lycopene and cancers. Recent case-control studies base on plasma level (µmol/l)<br />

Cancer sites Authors and<br />

year<br />

Colorectal polyps Shikany et al.,<br />

1997<br />

Breast Zhang et al.,<br />

1997<br />

Cervical dysplasia Nagata<br />

et al.,1999<br />

Country<br />

Design<br />

USA<br />

cases: 472; controls: 502<br />

USA<br />

cases: 46 controls: 63<br />

Japan<br />

cases: 156 controls: 156<br />

OR (CI) Trend Remarks<br />

H (>0.906) vs L (median. not defined)<br />

vs L (< median):<br />

OR: 0.32 (0.11-0.94)<br />

H (>0.9736) vs L<br />

(

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