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Processing and Bioavailability (WG2) page 46<br />

__________________________________________________________________________________________<br />

The level of absorption determined in these studies is hugely different, and so we have<br />

little reliable information at present to pass on to the industry and to the consumer. However,<br />

the involvement of scientists undertaking E.U. funded research in this area will facilitate<br />

access to new results which can be disseminated to the relevant industries via the activities of<br />

this Concerted Action.<br />

The currently available experimental data are not sufficient to recommend either the form<br />

of the food, processing strategy or dietary composition which will result in defined<br />

bioavailability.<br />

The results of the review prompt us to state that, so long as lycopene remains within the<br />

original hydrophilic matrix and, most of all, within a whole cell, it is considerably stable but<br />

that, precisely because of the subsequent scarce reactivity, it is probably less bioavailable and<br />

therefore it may be practically ineffective in exerting its potential antioxidant activity.<br />

Conversely, when lycopene solubilizes in a lipophilic matrix, it is considerably reactive and<br />

more available; therefore, it could efficiently perform its antioxidant activity. However, it is<br />

obvious that this higher reactivity renders it much more unprotected against the degradation<br />

activity of environmental conditions (air, biological matrix components, temperature).<br />

In conclusion, we can affirm tomato products represent an important, indeed the only,<br />

source of lycopene consumption both quantitatively (in amounts higher than those of fresh<br />

fruits which, in addition, are often eaten at an incomplete stage of ripeness, when the lycopene<br />

is present at lower levels) and qualitatively (i.e., in a form easier to attack and therefore more<br />

available). The preparation of sauces in the presence of oil or fat allows lycopene to be<br />

solubilized (particularly if the clot has no physical suitable defences, i.e. whole cell walls) and<br />

to be more available for humans.<br />

But it is also important to remember that, while lycopene in an aqueous matrix is very<br />

stable and therefore able to keep its potential for a long time, in a lipid matrix it is much more<br />

reactive and thus available, but also much more rapidly degradable.

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