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12 ileri kurs1 - Kan Merkezleri ve Transfüzyon Derneği

12 ileri kurs1 - Kan Merkezleri ve Transfüzyon Derneği

12 ileri kurs1 - Kan Merkezleri ve Transfüzyon Derneği

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Ulusal <strong>Kan</strong> <strong>Merkezleri</strong> <strong>ve</strong> <strong>Transfüzyon</strong> T›bb› Kursu XII - ‹leri Kurs<br />

ya da üstün duyarl›l›kta <strong>ve</strong> kan›n mikrobiyolojik taramas› için onaylanm›fl ikinci bir kiti kan merkezinde rutin olarak<br />

uygulayabilir ya da iflaretlenmifl kan ba¤›flç›lar›n›n taramas›nda kullanabilir. Test sonuçlar›na göre kan ba¤›flç›s› tekrar<br />

kabul edilse de, kay›tlar›, viral göstergenin önceki hatal› reakvitesini belirtecek flekilde muhafaza edilmelidir.<br />

Nötralizasyon ile do¤rulanamayan HBs Ag ya da tutars›z HBsAg, HBV DNA <strong>ve</strong> anti HBc sonuçlar› bulunan kan ba-<br />

¤›flç›lar›n›n tekrar kan örne¤i alt›nc› ayda al›nmal›d›r.<br />

<strong>Kan</strong> ba¤›flç›s›n›n test sonuçlar› HIV, HCV ya da HBV ile enfeksiyona iflaret ederse, kan merkezinde yap›lmas› gereken<br />

ifllemlere “lookback” denir. Bu ifllemler ayn› zamanda kan ba¤›flç›s›n›n pencere döneminde tarama testleri negatifken<br />

yapm›fl oldu¤u önceki ba¤›fllar› kapsar. Bunlar; stokta bulunan, halen kullan›lmam›fl, gün içindeki ba¤›fllar›n karantinaya<br />

al›nmas›, kan da¤›t›lan merkezlerin ba¤›flç›ya ait, zaman› içindeki bileflenler konusunda bilgilendirilmesi, kan<br />

ba¤›flç›s›n›n <strong>ileri</strong> testlerinin yap›lmas›, önceki ba¤›fllar›n etiketlerinin de¤ifltirilmesi <strong>ve</strong> imha edilmesi ile ba¤›flç›dan daha<br />

önce kan alm›fl olan al›c›lar›n bilgilendirilmesi ifllemleridir.<br />

KAYNAKLAR<br />

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costs. Editorial. Transfusion 2008; 48: 576-579.<br />

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HBc tests. Vox Sanguinis 206; 91: 237-243.<br />

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test results. 69th meeting-June 14-15 2001.<br />

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and donor deferrel and reentry. July 2005:p1-24.<br />

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Prism antibody to hepatitis B core antigen assay. Transfusion 2009; 49: 271-277.<br />

11. Christensen PB, Titlestad IL, Homburg KM, et al. Hepatitis B core antibodies in Danish blood donors: a surrogate<br />

marker of risk behaviour. Vox Sanguinis 2001; 81: 222-227.<br />

<strong>12</strong>. Bhatti FA, Ullah Z, Salamat N, et al. Anti hepatitis B core antigen testing, viral markers and occult hepatitis B<br />

infection in Pakistani blood donors: implications for transfusion practice. Transfusion 2007; 47: 74-79.<br />

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transmitted-hepatitis B virus. Swiss Med Wkly 2008; 138 (9-10): 134-141.<br />

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recommendations for management of donors and units testing positi<strong>ve</strong> for hepatitis B virus DNA. Vox Sangui-<br />

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