Table of Contents - WOC 2012

WOC2012 Abstract Book
IS-SOS-FR 68 (3)
Fitting Post-Rings Patients
Tanal Liliane (1)
1. Medicals International
Keratoconus is a corneal ectatic disease that is characterized by
noninflammatory progressive thinning. Intracorneal ring segments have been
used to correct keratoconus. The aim of implanting intracorneal ring segments
is to decrease the astigmatism and corneal abnormality and thus increase the
visual acuity to acceptable limits. Contact lenses are still required after the
insertion of corneal rings in some patients with postoperative decreased vision.
If a successful fit is obtained, the vision can be significantly improved with
specialty contact lens fitting.
IS-SOS-FR 68 (4)
Keratoconus Case Presentation (Scleral Lenses)
Aldelaigan Bassima (1)
1. BIN RUSHD Specialist Centre
Case presentation of a 33 year old male with keratoglobus in both eyes.
Clinical findings and topography maps will be presented. The indications and
guidelines as well as clinical tips for fitting scleral lenses in such cases will be
reviewed.
IS-SOS-FR 68 (5)
Soft Contact Lens Compliance Issues
Walker Johnthan (1)
1. Jonathan Walker & Associates
A review will be presented of the complications found in soft contact lens wear
and their subsequent management, with concentration on the new Silicone
hydrogel materials. The main complication seen is discomfort, caused by
contact lens induced evaporative dry eye. An analyses will be made of causes,
and the effect upon the normal tear film. The second complication is that of
Solution Induced Corneal Staining (SICS). The occurrence of this toxic reaction
and its relevance and management will be explained.
Novel Treatments for Diabetic Retinopathy and Diabetic Macular
Edema
Fri 17 Feb 8:30 - 10:00 Capital Suite 7
IS-EVI-FR 69 (1)
Systemic Treatments for Diabetic Retinopathy and Macular Edema
Wong Tien Yin (1)
1. Singapore Eye Research Institute
Diabetic retinopathy is a major cause of blindness. While there is robust
evidence that optimal control of blood glucose and blood pressure reduces
the risk of retinopathy development and progression, several key questions
remain. First, what are the target glycaemia and blood pressure levels for
effective prevention of retinopathy development and progression? Second,
are certain blood pressure-lowering agents more effective than others for
retinopathy? Third, what is the role of lipid-lowering agents? Finally, how
effective is multi-modality systemic management?
IS-EVI-FR 69 (2)
Anti-VEGF Treatments for Diabetic Macular Edema
Mitchell Paul (1)
1. Westmead Millennium Institute, University of Sydney
Abstract not available
102
IS-EVI-FR 69 (3)
Do Intraocular Steroids Still Have a Role in Management of Diabetic
Macular Edema?
Jonas Jost (1)
1. Department of Ophthalmology
Purpose: To discuss the use of intravitreally applied steroids in the treatment of
diabetic macular edema.
Methods / Results: The results of previous trials will be presented and the
advantages and disadvantages of intravitreal steroids will be discussed.
Conclusions: Intravitreal steroids still have a place in the treatment of diabetic
macular edema.
IS-EVI-FR 69 (4)
Micropulse Laser for Diabetic Macular, Edema Fact or Fiction?
Okonkwo Ogugua (1)
1. Eye Foundation Center
The Early Treatment Diabetic Retinopath Study (ETDRS) established the
value of retinal laser photocoagulation in treating Diabetic Macula Edema
(DME). Since then, laser has been the gold standard. The mechanism of action
of laser photocoagulation is being debated. Proposed cellular response theory
questions continued use of suprathreshold laser. Micropulse laser delivers
subthreshold burns, has an invisible tissue effect and significant tissue sparing.
It reduces collateral damage, with a therapeutic effect. Clinical evidence and
data on this form of treatment is reviewed.
IS-EVI-FR 69 (5)
The Impact of Laser and Anti-VEGF Treatment Modalities on Quality
of Life Domains: Current Evidence, Limitations, and Future Research
Lamourex Ecosse (1,2) , Fenwick E. (1) , Pesudovs K. (3) , Wong T.Y. (1,2)
1. Centre for Eye Research Australia, University of Melbourne, the Royal Victorian
Eye and Ear Hospital
2. NH&MRC Centre for Clinical Eye Research, Discipline of Optometry and Vision
Science, Flinders University and Flinders Medical Centre
3. Singapore Eye Research Institute, Singapore National Eye Centre
Laser surgery is the current mainstay of treatment for severe non-proliferative
and proliferative diabetic retinopathy (DR) and diabetic macular edema (DME).
Recently, studies have also demonstrated the effectiveness of anti-vascular
endothelial growth factor (anti-VEGF) therapy in the treatment of end stage DR
and DME. While studies have shown that laser therapy is extremely successful
in preventing significant vision loss and anti-VEGF treatment has produced
substantial gains in visual acuity, the patient-centered impact of these
treatment protocols remains unclear. From the limited current evidence, both
therapies appear to have a beneficial effect on patients› subjective perception
of health-related quality of life (QoL). The most frequently assessed patientcentered
trait has been ‹activity limitation ‹or ‹vision-specific functioning› and
improvements in composite scores have been recorded over follow-up periods
of up to 12 months mostly using the NEI-VFQ scale. What is critically lacking,
however, is an understanding of how these two treatment modalities impact on
other QoL domains such as ocular surface symptoms, emotional well-being,
health concerns, social, mobility, convenience, and economic parameters.
There is currently no DR-specific instrument available that comprehensively
covers the QoL domains specific to patients living with this condition. We are
currently developing the first item bank for DR and DME which comprises over
300 items (questions) tapping into 9 specific QoL domains. The future role of
this new instrument to comprehensively assess the impact of laser and anti-
VEGF modalities on patients› QoL will be discussed.
IS-EVI-FR 69 (6)
Treatments for Diabetic Retinopathy: Quality Effect Model Analysis
Bouhaimed Manal
A quality-effects approach that combines evidence from a series of trials
comparing 2 interventions as applicable to Diabetic Retinopathy treatment
modalities will be introduced. This approach incorporates the heterogeneity of
effects in the analysis of the overall interventional efficacy and could represent
a more convincing alternative to the random effects model.